Web Proteomics Resources 

Two comprehensive protein resource center:

ExPASy  (Expert Protein Analysis System)

PIR (Protein Information Resource)

Protein Databases

Sequence databases

SWISS-PROT SWISS-PROT annotated protein sequence db
TrEMBL Computer-annotated supplement to SWISS-PROT
PSD PIR Protein Sequence Database

Domain structure

PROSITE PROSITE dictionary of protein sites and patterns

PRINTS Protein Motif fingerprint database

InterPro Integrated Resources of Proteins Domains and Functional Sites

DOMO - Protein domain database in France (Automatically generated)

BMM Domain Server - Biomolecular Modelling Laboratory (ICRF) protein domain server

BLOCKS Blocks database

ProDOM Protein domain database (Automatically generated)

SMART Simple Modular Architecture Research Tool

Three-dimensional structure

PDB Protein Data Bank

SWISS-MODEL Automatically generated protein models db

MODBASE Db of comparative protein structure models

SCOP Structural classification of proteins

CATH  UCL BSM structural classification of proteins

3DCrunch a Very Large Scale Protein Modelling Project

VAST  NCBI's structure-structure similarity search service

SWISS-3DIMAGE - 3D images of proteins and other biological macromolecules

Protein 2D-PAGE databases

WORLD-2DPAGE  The most comprehensive Index to 2-D PAGE databases and services

Tools for Protein Identification

Protein Prospector  Proteomics tools for mining sequence databases  in conjunction with Mass Spectrometry experiments

PepSea  an advanced tool for protein database searching by mass spectrometric data, such as peptide mass maps or (partial) amino acid sequences. 

PeptIdent  allows the identification of proteins using pI, Mw and peptide mass fingerprinting data (on ExPASy)

FindPept identify peptides that result from unspecific cleavage of proteins from their experimental masses (on ExPASy)

Profound protein identification by comparison of a peptide map to NCBI's nr databases using a Bayesian algorithm

PepFrag  protein identification by comparison of the fragmentation pattern of proteolytic peptides to a database

Mascot a powerful search engine which uses mass spectrometry data to identify proteins from primary sequence databases.

SEQUEST

Protein-Protein Interaction Projects and Resources

DIP Database of Interacting Proteins

INTERACT Protein-Protein interaction project in Manchester
ProNet Protein-Protein interaction database (Myriad Genetics)
ProMesh Protein-Protein Interaction Database in the University of Queensland
BIND Biomolecular Interaction Network Database

Research Centres

Harvard Institute of Proteomics
Joint Protein Structure Laboratory-Australia
Proteomics Project at the Argonne National Laboratory
Genome Science & Technology Graduate School of The University of Tennessee and the Oak Ridge National Lab
EMBL Protein and Peptide Group PeptideSearch
SwissProt Human Proteomics Initiative
Munich Information Centre for Protein Science (MIPS)
NIH Molecular Profiling Initiative

Proteomic Companies List  (Recommended!)

Other links

PSORT-II  a computer program for the prediction of protein localization sites in cells