Web Proteomics Resources
Two comprehensive protein resource center:
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ExPASy (Expert Protein Analysis System) | |
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PIR (Protein Information Resource) |
Protein Databases
Sequence databases
| SWISS-PROT SWISS-PROT annotated protein sequence db | |
| TrEMBL Computer-annotated supplement to SWISS-PROT | |
| PSD PIR Protein Sequence Database |
Domain structure
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PROSITE PROSITE dictionary of protein sites and patterns | |
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PRINTS Protein Motif fingerprint database | |
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InterPro Integrated Resources of Proteins Domains and Functional Sites | |
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DOMO - Protein domain database in France (Automatically generated) | |
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BMM Domain Server - Biomolecular Modelling Laboratory (ICRF) protein domain server | |
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BLOCKS Blocks database | |
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ProDOM Protein domain database (Automatically generated) | |
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SMART Simple Modular Architecture Research Tool |
Three-dimensional structure
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PDB Protein Data Bank | |
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SWISS-MODEL Automatically generated protein models db | |
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MODBASE Db of comparative protein structure models | |
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SCOP Structural classification of proteins | |
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CATH UCL BSM structural classification of proteins | |
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3DCrunch a Very Large Scale Protein Modelling Project | |
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VAST NCBI's structure-structure similarity search service | |
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SWISS-3DIMAGE - 3D images of proteins and other biological macromolecules |
Protein 2D-PAGE databases
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WORLD-2DPAGE The most comprehensive Index to 2-D PAGE databases and services |
Tools for Protein Identification
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Protein Prospector Proteomics tools for mining sequence databases in conjunction with Mass Spectrometry experiments | |
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PepSea an advanced tool for protein database searching by mass spectrometric data, such as peptide mass maps or (partial) amino acid sequences. | |
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PeptIdent allows the identification of proteins using pI, Mw and peptide mass fingerprinting data (on ExPASy) | |
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FindPept identify peptides that result from unspecific cleavage of proteins from their experimental masses (on ExPASy) | |
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Profound protein identification by comparison of a peptide map to NCBI's nr databases using a Bayesian algorithm | |
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PepFrag protein identification by comparison of the fragmentation pattern of proteolytic peptides to a database | |
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Mascot a powerful search engine which uses mass spectrometry data to identify proteins from primary sequence databases. | |
Protein-Protein Interaction Projects and Resources
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DIP Database of Interacting Proteins | |
| INTERACT Protein-Protein interaction project in Manchester | |
| ProNet Protein-Protein interaction database (Myriad Genetics) | |
| ProMesh Protein-Protein Interaction Database in the University of Queensland | |
| BIND Biomolecular Interaction Network Database |
Research Centres
Proteomic Companies List (Recommended!)
Other links
PSORT-II a computer program for the prediction of protein localization sites in cells