Number of amino acids: 7073

Molecular weight: 790324.4

Theoretical pI: 6.21

Amino acid composition:

Ala (A) 511	  7.2%
Arg (R) 260	  3.7%
Asn (N) 366	  5.2%
Asp (D) 395	  5.6%
Cys (C) 233	  3.3%
Gln (Q) 233	  3.3%
Glu (E) 347	  4.9%
Gly (G) 419	  5.9%
His (H) 160	  2.3%
Ile (I) 343	  4.8%
Leu (L) 674	  9.5%
Lys (K) 415	  5.9%
Met (M) 177	  2.5%
Phe (F) 331	  4.7%
Pro (P) 274	  3.9%
Ser (S) 458	  6.5%
Thr (T) 495	  7.0%
Trp (W)  77	  1.1%
Tyr (Y) 325	  4.6%
Val (V) 580	  8.2%

Asx (B)   0	  0.0%
Glx (Z)   0	  0.0%
Xaa (X)   0	  0.0%

Total number of negatively charged residues (Asp + Glu): 742
Total number of positively charged residues (Arg + Lys): 675

Atomic composition:

Carbon      C	     35386
Hydrogen    H	     55010
Nitrogen    N	      9264
Oxygen      O	     10435
Sulfur      S	       410

Formula: C35386H55010N9264O10435S410
Total number of atoms: 110505

Extinction coefficients:

Conditions: 6.0 M guanidium hydrochloride
            0.02 M phosphate buffer
            pH 6.5

Extinction coefficients are in units of  M-1 cm-1 .

The first table lists values computed assuming ALL Cys 
residues appear as half cystines, whereas the second table 
assumes that NONE do. 

                      276     278     279     280     282
                       nm      nm      nm      nm      nm
Ext. coefficient   903870  900932  886865  868050  835120
Abs 0.1% (=1 g/l)   1.144   1.140   1.122   1.098   1.057



                      276     278     279     280     282
                       nm      nm      nm      nm      nm
Ext. coefficient   887050  886200  872945  854130  821200
Abs 0.1% (=1 g/l)   1.122   1.121   1.105   1.081   1.039


Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 33.63
This classifies the protein as stable.



Aliphatic index: 87.08

Grand average of hydropathicity (GRAVY): -0.070