putative
uncharacterized protein [SARS coronavirus]
Source Data: (From: http://us.expasy.org)
Physical Attributes:
Number of amino acids: 122
Molecular weight: 13941.3
Theoretical pI: 8.24
Amino acid composition:
Ala (A) 8 6.6%
Arg (R) 6 4.9%
Asn (N) 2 1.6%
Asp (D) 2 1.6%
Cys (C) 6 4.9%
Gln (Q) 5 4.1%
Glu (E) 8 6.6%
Gly (G) 4 3.3%
His (H) 4 3.3%
Ile (I) 7 5.7%
Leu (L) 16 13.1%
Lys (K) 6 4.9%
Met (M) 1 0.8%
Phe (F) 10 8.2%
Pro (P) 6 4.9%
Ser (S) 7 5.7%
Thr (T) 12 9.8%
Trp (W) 0 0.0%
Tyr (Y) 5 4.1%
Val (V) 7 5.7%
Asx (B) 0 0.0%
Glx (Z) 0 0.0%
Xaa (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 10
Total number of positively charged residues (Arg + Lys): 12
Atomic composition:
Carbon C 639
Hydrogen H 995
Nitrogen N 161
Oxygen O 174
Sulfur S 7
Formula: C639H995N161O174S7
Total number of atoms: 1976
Extinction coefficients:
Conditions: 6.0 M guanidium hydrochloride
0.02 M phosphate buffer
pH 6.5
Extinction coefficients are in units of M-1 cm-1 .
The first table lists values computed assuming ALL Cys
residues appear as half cystines, whereas the second table
assumes that NONE do.
276 278 279 280 282
nm nm nm nm nm
Ext. coefficient 7685 7381 7085 6760 6360
Abs 0.1% (=1 g/l) 0.551 0.529 0.508 0.485 0.456
276 278 279 280 282
nm nm nm nm nm
Ext. coefficient 7250 7000 6725 6400 6000
Abs 0.1% (=1 g/l) 0.520 0.502 0.482 0.459 0.430
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 58.27
This classifies the protein as unstable.
Aliphatic index: 96.72
Grand average of hydropathicity (GRAVY): 0.218
Protein Sequence Feature:
Note: click items to see a description.
Drag two red cursors to select a zoom region.