Number of amino acids: 179
Molecular weight: 19583.0
Theoretical pI: 5.35
Amino acid composition:
Ala (A) 7 3.9%
Arg (R) 9 5.0%
Asn (N) 9 5.0%
Asp (D) 9 5.0%
Cys (C) 1 0.6%
Gln (Q) 6 3.4%
Glu (E) 17 9.5%
Gly (G) 22 12.3%
His (H) 7 3.9%
Ile (I) 6 3.4%
Leu (L) 24 13.4%
Lys (K) 9 5.0%
Met (M) 2 1.1%
Phe (F) 2 1.1%
Pro (P) 6 3.4%
Ser (S) 10 5.6%
Thr (T) 8 4.5%
Trp (W) 1 0.6%
Tyr (Y) 6 3.4%
Val (V) 18 10.1%
Asx (B) 0 0.0%
Glx (Z) 0 0.0%
Xaa (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 26
Total number of positively charged residues (Arg + Lys): 18
Atomic composition:
Carbon C 860
Hydrogen H 1379
Nitrogen N 245
Oxygen O 271
Sulfur S 3
Formula: C860H1379N245O271S3
Total number of atoms: 2758
Extinction coefficients:
Conditions: 6.0 M guanidium hydrochloride
0.02 M phosphate buffer
pH 6.5
Extinction coefficients are in units of M-1 cm-1 .
The first table lists values computed assuming ALL Cys
residues appear as half cystines, whereas the second table
assumes that NONE do.
276 278 279 280 282
nm nm nm nm nm
Ext. coefficient 14100 14000 13730 13370 12800
Abs 0.1% (=1 g/l) 0.720 0.715 0.701 0.683 0.654
276 278 279 280 282
nm nm nm nm nm
Ext. coefficient 14100 14000 13730 13370 12800
Abs 0.1% (=1 g/l) 0.720 0.715 0.701 0.683 0.654
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 26.71
This classifies the protein as stable.
Aliphatic index: 98.44
Grand average of hydropathicity (GRAVY): -0.357
Protein Sequence Feature:
Note: click items to see a description.
Drag two red cursors to select a zoom region.