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                  Welcome to the SIB BLAST Network Service

If results of this search are reported or published, please mention that
the computation was performed at the SIB using the BLAST network service.
The SIB BLAST network service uses a server developed at SIB and the NCBI
BLAST 2 software. It is implemented on hardware provided by HP.

In case of problems, please contact us.

NCBI BLAST program reference [PMID:9254694]:
Altschul S.F., Madden T.L., Schäffer A.A., Zhang J., Zhang Z., Miller W.,
Lipman D.J.  Gapped BLAST and PSI-BLAST: a new generation of protein
database search programs.  Nucleic Acids Res. 25:3389-3402(1997).

============================================================================

Query length: 139 AA
Date run: 2003-05-01 15:04:18 UTC+0100 on sib-blast.unil.ch
Program: NCBI BLASTP 2.2.5 [Nov-16-2002]
Database: XXswissprot Viruses 
           8482 sequences; 3,552,911 total letters
           Swiss-Prot Release 41.6 of 30-Apr-2003




List of potentially matching sequences
Send selected sequences to

Include query sequence 

  Db AC     Description                                            Score E-value

 sp P59641 R1AB_CVHSA Replicase polyprotein 1ab (pp1ab) (ORF1AB) ... 306 1e-84
 sp P19751 RRPA_CVMJH RNA-directed RNA polymerase (ORF1A) (EC 2.7... 170 9e-44
 sp P27920 VGF1_IBVB F1 protein [F1] [Avian infectious bronchitis... 166 1e-42
 sp Q05002 R1AB_CVH22 Replicase polyprotein 1ab (pp1ab) (ORF1AB) ... 160 6e-41
 sp P41356 VGLF_RINDR Fusion glycoprotein precursor [Contains: Fu...  26   2.1
 sp P12574 VGLF_RINDK Fusion glycoprotein precursor [Contains: Fu...  26   2.1
 sp P41360 VGLF_RINDB Fusion glycoprotein precursor [Contains: Fu...  26   2.1
 sp P06828 VGLF_PI3H4 Fusion glycoprotein precursor [Contains: Fu...  26   2.1
 sp P28886 VGLF_PHODV Fusion glycoprotein precursor [Contains: Fu...  25   3.7
 sp P27282 POLN_EEVVT Nonstructural polyprotein [Contains: Nonstr...  25   3.7
 sp P36328 POLN_EEVVP Nonstructural polyprotein [Contains: Nonstr...  25   3.7
 sp P36327 POLN_EEVV3 Nonstructural polyprotein [Contains: Nonstr...  25   3.7
 sp P10864 VGLF_RINDL Fusion glycoprotein precursor [Contains: Fu...  25   4.8
 sp P26032 VGLF_MEASY Fusion glycoprotein precursor [Contains: Fu...  25   4.8
 sp P08300 VGLF_MEASE Fusion glycoprotein precursor [Contains: Fu...  25   4.8
 sp P35973 VGLF_MEASA Fusion glycoprotein precursor [Contains: Fu...  25   4.8
 sp P12569 VGLF_CDVO Fusion glycoprotein precursor [Contains: Fus...  25   4.8
 sp O72539 DPOL_ADEB2 DNA polymerase (EC 2.7.7.7) [POL] [Bovine a...  25   4.8
 sp P26031 VGLF_MEASI Fusion glycoprotein precursor [Contains: Fu...  25   6.2
 sp P36848 FIBP_ADE31 Fiber protein [PIV] [Human adenovirus type 31]  24   8.1



Alignments



spP59641
R1AB_CVHSA		Replicase polyprotein 1ab (pp1ab) (ORF1AB) [Includes: Replicase
            polyprotein 1a (pp1a) (ORF1A)] [Contains: Leader protein;
            p65 homolog; Papain-like proteinase (EC 3.4.24.-) (NSP1);
            3C-like proteinase (EC 3.4.24.-) (3CL-PRO) (NSP2); HD2
            (NSP3); NSP4; NSP5; NSP6; Growth factor-like (NSP7);
            RNA-directed RNA polymerase (EC 2.7.7.48) (RdRp) (NSP9);
            Helicase (Hel) (NSP10); NSP11; NSP12; NSP13] [Human
            coronavirus (strain SARS) (HCoV-SARS)]		          7073 AA 
align
 Score =  306 bits (783), Expect = 1e-84
 Identities = 139/139 (100%), Positives = 139/139 (100%)

Query: 1    AGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 60
            AGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE
Sbjct: 4231 AGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4290

Query: 61   ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVC 120
            ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVC
Sbjct: 4291 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVC 4350

Query: 121  GMWKGYGCSCDQLREPLMQ 139
            GMWKGYGCSCDQLREPLMQ
Sbjct: 4351 GMWKGYGCSCDQLREPLMQ 4369






spP19751
RRPA_CVMJH		RNA-directed RNA polymerase (ORF1A) (EC 2.7.7.48) [Murine coronavirus
            MHV (strain JHM)]		          4488 AA 
align
 Score =  170 bits (430), Expect = 9e-44
 Identities = 73/130 (56%), Positives = 92/130 (70%), Gaps = 1/130 (0%)

Query: 1    AGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 60
            AG ATE  +NS +LS CAF+VDP K Y DY+  GG P+TNCVKMLC H GTG AIT+ PE
Sbjct: 4338 AGTATEYASNSAILSLCAFSVDPKKTYLDYIQQGGVPVTNCVKMLCDHAGTGMAITIKPE 4397

Query: 61   ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVC 120
            A  +Q+S+GGAS C+YCR  ++HP+  G C L+GK+VQ+P     DPV + L + VC VC
Sbjct: 4398 ATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPLG-IKDPVSYVLTHDVCQVC 4456

Query: 121  GMWKGYGCSC 130
            G W+   CSC
Sbjct: 4457 GFWRDGSCSC 4466






spP27920
VGF1_IBVB		F1 protein [F1] [Avian infectious bronchitis virus (strain Beaudette)
            (IBV)]		          3951 AA 
align
 Score =  166 bits (420), Expect = 1e-42
 Identities = 81/139 (58%), Positives = 92/139 (66%), Gaps = 5/139 (3%)

Query: 2    GNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEA 61
            G+ TE      +LS C+FAVDPA  Y  Y+A+G QP+ NCVKML  H G+G AIT  P  
Sbjct: 3786 GHETEEVDAVGILSLCSFAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPSP 3845

Query: 62   NMDQESFGGASCCLYCRCHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVC 117
              DQ+S+GGAS CLYCR HI HP    N  G C  KG +VQIPTT   DPVGF LRN VC
Sbjct: 3846 TPDQDSYGGASVCLYCRAHIAHPGSVGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKVC 3904

Query: 118  TVCGMWKGYGCSCDQLREP 136
            TVC  W GYGC CD LR+P
Sbjct: 3905 TVCQCWIGYGCQCDSLRQP 3923






spQ05002
R1AB_CVH22		Replicase polyprotein 1ab (pp1ab) (ORF1AB) [Includes: Replicase
            polyprotein 1a (pp1a) (ORF1A)] [Contains: Protein p9;
            Papain-like proteinase 1 (EC 3.4.24.-); Papain-like
            proteinase 2 (EC 3.4.24.-); 3C-like proteinase (EC
            3.4.24.-) (3CL-PRO); RNA-directed RNA polymerase (EC
            2.7.7.48) (RdRp); Helicase (Hel)] [Human coronavirus
            (strain 229E) (HCoV-229E)]		          6758 AA 
align
 Score =  160 bits (406), Expect = 6e-41
 Identities = 71/132 (53%), Positives = 93/132 (70%), Gaps = 1/132 (0%)

Query: 1    AGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 60
            AG  TE  +NS +L+ C+FAVDPA AY D +  G +P+ NCVKML   +G+GQAIT T +
Sbjct: 3934 AGKQTEFVSNSHLLTHCSFAVDPAAAYLDAVKQGAKPVGNCVKMLTNGSGSGQAITCTID 3993

Query: 61   ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVC 120
            +N  Q+++GGAS C+YCR H+ HP   GFC  KGK+VQ+P    NDP+ F L NTVC VC
Sbjct: 3994 SNTTQDTYGGASVCIYCRAHVAHPTMDGFCQYKGKWVQVPIG-TNDPIRFCLENTVCKVC 4052

Query: 121  GMWKGYGCSCDQ 132
            G W  +GC+CD+
Sbjct: 4053 GCWLNHGCTCDR 4064






spP41356
VGLF_RINDR		Fusion glycoprotein precursor [Contains: Fusion glycoprotein F2;
           Fusion glycoprotein F1] [F] [Rinderpest virus (strain
           RBOK) (RDV)]		          546 AA 
align
 Score = 26.2 bits (56), Expect = 2.1
 Identities = 13/44 (29%), Positives = 19/44 (43%)

Query: 17  CAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 60
           CA  +        ++ S G  I NC  +LC    TG  I+  P+
Sbjct: 362 CARTLVSGSIGNRFILSKGNLIANCASILCKCYTTGSIISQDPD 405






spP12574
VGLF_RINDK		Fusion glycoprotein precursor [Contains: Fusion glycoprotein F2;
           Fusion glycoprotein F1] [F] [Rinderpest virus (strain
           Kabete O) (RDV)]		          546 AA 
align
 Score = 26.2 bits (56), Expect = 2.1
 Identities = 13/44 (29%), Positives = 19/44 (43%)

Query: 17  CAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 60
           CA  +        ++ S G  I NC  +LC    TG  I+  P+
Sbjct: 362 CARTLVSGSIGNRFILSKGNLIANCASILCKCYTTGSIISQDPD 405






spP41360
VGLF_RINDB		Fusion glycoprotein precursor [Contains: Fusion glycoprotein F2;
           Fusion glycoprotein F1] [F] [Rinderpest virus (strain
           RBT1) (RDV)]		          546 AA 
align
 Score = 26.2 bits (56), Expect = 2.1
 Identities = 13/44 (29%), Positives = 19/44 (43%)

Query: 17  CAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 60
           CA  +        ++ S G  I NC  +LC    TG  I+  P+
Sbjct: 362 CARTLVSGSIGNRFILSKGNLIANCASILCKCYTTGSIISQDPD 405






spP06828
VGLF_PI3H4		Fusion glycoprotein precursor [Contains: Fusion glycoprotein F2;
           Fusion glycoprotein F1] [F] [Human parainfluenza 3 virus
           (strain NIH 47885)]		          539 AA 
align
 Score = 26.2 bits (56), Expect = 2.1
 Identities = 13/47 (27%), Positives = 18/47 (38%)

Query: 14  LSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 60
           +S C   V  +     Y    G  + NC+   CT  G G  I   P+
Sbjct: 360 ISQCPRTVVKSDIVPRYAFVNGGVVANCITTTCTCNGIGNRINQPPD 406






spP28886
VGLF_PHODV		Fusion glycoprotein precursor [Contains: Fusion glycoprotein F2;
           Fusion glycoprotein F1] [F] [Phocine distemper virus
           (PDV)]		          631 AA 
align
 Score = 25.4 bits (54), Expect = 3.7
 Identities = 12/44 (27%), Positives = 19/44 (43%)

Query: 17  CAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 60
           CA  +        ++ S G  I NC  +LC    T + I  +P+
Sbjct: 447 CARTLVSGTLGNKFILSKGNIIANCASILCKCHSTSKIINQSPD 490






spP27282
POLN_EEVVT		Nonstructural polyprotein [Contains: Nonstructural protein NSP1;
            Nonstructural protein NSP2; Nonstructural protein NSP3;
            Nonstructural protein NSP4] [Venezuelan equine
            encephalitis virus (strain Trinidad donkey)]		          2492 AA 
align
 Score = 25.4 bits (54), Expect = 3.7
 Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 13/99 (13%)

Query: 41   CVKMLCTHTGTGQAITVTPEANMDQESFGGASCCL----YCRCHIDHPNPKGFCDLKGKY 96
            C  ML  +  T  +  + PE +   +   GASCCL    +C   +    PK     K  Y
Sbjct: 2009 CNAMLKENFPTVASYCIIPEYDAYLDMVDGASCCLDTASFCPAKL-RSFPK-----KHSY 2062

Query: 97   VQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLRE 135
            ++ PT      V   ++NT+  V        C+  Q+RE
Sbjct: 2063 LE-PT--IRSAVPSAIQNTLQNVLAAATKRNCNVTQMRE 2098






spP36328
POLN_EEVVP		Nonstructural polyprotein [Contains: Nonstructural protein NSP1;
            Nonstructural protein NSP2; Nonstructural protein NSP3;
            Nonstructural protein NSP4] [Venezuelan equine
            encephalitis virus (strain P676)]		          2492 AA 
align
 Score = 25.4 bits (54), Expect = 3.7
 Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 13/99 (13%)

Query: 41   CVKMLCTHTGTGQAITVTPEANMDQESFGGASCCL----YCRCHIDHPNPKGFCDLKGKY 96
            C  ML  +  T  +  + PE +   +   GASCCL    +C   +    PK     K  Y
Sbjct: 2009 CNAMLKENFPTVASYCIIPEYDAYLDMVDGASCCLDTASFCPAKL-RSFPK-----KHSY 2062

Query: 97   VQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLRE 135
            ++ PT      V   ++NT+  V        C+  Q+RE
Sbjct: 2063 LE-PT--IRSAVPSAIQNTLQNVLAAATKRNCNVTQMRE 2098






spP36327
POLN_EEVV3		Nonstructural polyprotein [Contains: Nonstructural protein NSP1;
            Nonstructural protein NSP2; Nonstructural protein NSP3;
            Nonstructural protein NSP4] [Venezuelan equine
            encephalitis virus (strain 3880)]		          2485 AA 
align
 Score = 25.4 bits (54), Expect = 3.7
 Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 13/99 (13%)

Query: 41   CVKMLCTHTGTGQAITVTPEANMDQESFGGASCCL----YCRCHIDHPNPKGFCDLKGKY 96
            C  ML  +  T  +  + PE +   +   GASCCL    +C   +    PK     K  Y
Sbjct: 2002 CNAMLKENFPTVASYCIIPEYDAYLDMVDGASCCLDTASFCPAKL-RSFPK-----KHSY 2055

Query: 97   VQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLRE 135
            ++ PT      V   ++NT+  V        C+  Q+RE
Sbjct: 2056 LE-PT--IRSAVPSAIQNTLQNVLAAATKRNCNVTQMRE 2091






spP10864
VGLF_RINDL		Fusion glycoprotein precursor [Contains: Fusion glycoprotein F2;
           Fusion glycoprotein F1] [F] [Rinderpest virus (strain L)
           (RDV)]		          546 AA 
align
 Score = 25.0 bits (53), Expect = 4.8
 Identities = 11/31 (35%), Positives = 16/31 (51%)

Query: 30  YLASGGQPITNCVKMLCTHTGTGQAITVTPE 60
           ++ S G  I NC  +LC    TG  I+  P+
Sbjct: 375 FILSKGNLIGNCASILCKCYTTGSIISQDPD 405






spP26032
VGLF_MEASY		Fusion glycoprotein precursor [Contains: Fusion glycoprotein F2;
           Fusion glycoprotein F1] [F] [Measles virus (strain
           Yamagata-1) (Subacute sclerose panencephalitis virus)]		          534 AA 
align
 Score = 25.0 bits (53), Expect = 4.8
 Identities = 11/31 (35%), Positives = 15/31 (48%)

Query: 30  YLASGGQPITNCVKMLCTHTGTGQAITVTPE 60
           ++ S G  I NC  +LC    TG  I   P+
Sbjct: 379 FILSQGNLIANCASILCKCYTTGTIINQDPD 409






spP08300
VGLF_MEASE		Fusion glycoprotein precursor [Contains: Fusion glycoprotein F2;
           Fusion glycoprotein F1] [F] [Measles virus (strain
           Edmonston) (Subacute sclerose panencephalitis virus),
           Measles virus (strain Halle) (Subacute sclerose
           panencephalitis virus), Measles virus (strain
           Leningrad-16) (Subacute sclerose panencephalitis virus),
           Measles virus (strain Edmonston-Zagreb) (Subacute
           sclerose panencephalitis virus), Measles virus (strain
           Philadelphia-26) (Subacute sclerose panencephalitis
           virus), Measles virus (strain Edmonston B) (Subacute
           sclerose panencephalitis virus)]		          550 AA 
align
 Score = 25.0 bits (53), Expect = 4.8
 Identities = 11/31 (35%), Positives = 15/31 (48%)

Query: 30  YLASGGQPITNCVKMLCTHTGTGQAITVTPE 60
           ++ S G  I NC  +LC    TG  I   P+
Sbjct: 379 FILSQGNLIANCASILCKCYTTGTIINQDPD 409






spP35973
VGLF_MEASA		Fusion glycoprotein precursor [Contains: Fusion glycoprotein F2;
           Fusion glycoprotein F1] [F] [Measles virus (strain
           AIK-C) (Subacute sclerose panencephalitis virus)]		          550 AA 
align
 Score = 25.0 bits (53), Expect = 4.8
 Identities = 11/31 (35%), Positives = 15/31 (48%)

Query: 30  YLASGGQPITNCVKMLCTHTGTGQAITVTPE 60
           ++ S G  I NC  +LC    TG  I   P+
Sbjct: 379 FILSQGNLIANCASILCKCYTTGTIINQDPD 409






spP12569
VGLF_CDVO		Fusion glycoprotein precursor [Contains: Fusion glycoprotein F2;
           Fusion glycoprotein F1] [F] [Canine distemper virus
           (strain Onderstepoort) (CDV)]		          662 AA 
align
 Score = 25.0 bits (53), Expect = 4.8
 Identities = 12/46 (26%), Positives = 19/46 (41%)

Query: 15  SFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 60
           S CA  +        ++ S G  + NC  +LC    T   I  +P+
Sbjct: 476 SSCARTLVSGTMGNKFILSKGNIVANCASILCKCYSTSTIINQSPD 521






spO72539
DPOL_ADEB2		DNA polymerase (EC 2.7.7.7) [POL] [Bovine adenovirus type 2
           (Mastadenovirus bos2)]		          1017 AA 
align
 Score = 25.0 bits (53), Expect = 4.8
 Identities = 9/15 (60%), Positives = 11/15 (73%)

Query: 107 PVGFTLRNTVCTVCG 121
           P  + L+NTVCT CG
Sbjct: 894 PKLYALKNTVCTCCG 908






spP26031
VGLF_MEASI		Fusion glycoprotein precursor [Contains: Fusion glycoprotein F2;
           Fusion glycoprotein F1] [F] [Measles virus (strain
           IP-3-Ca) (Subacute sclerose panencephalitis virus)]		          529 AA 
align
 Score = 24.6 bits (52), Expect = 6.2
 Identities = 11/31 (35%), Positives = 15/31 (48%)

Query: 30  YLASGGQPITNCVKMLCTHTGTGQAITVTPE 60
           ++ S G  I NC  +LC    TG  I   P+
Sbjct: 382 FILSQGNLIANCASILCKCYTTGTIIRQDPD 412






spP36848
FIBP_ADE31		Fiber protein [PIV] [Human adenovirus type 31]          556 AA 
align
 Score = 24.3 bits (51), Expect = 8.1
 Identities = 12/34 (35%), Positives = 17/34 (50%)

Query: 36  QPITNCVKMLCTHTGTGQAITVTPEANMDQESFG 69
           QP T  V +       G+ +T TP A + Q S+G
Sbjct: 427 QPTTTTVGLHLVFDRQGRLVTTTPTALVPQASWG 460





Database: XXswissprot Viruses
    Posted date:  Apr 29, 2003 11:07 AM
  Number of letters in database: 3,552,911
  Number of sequences in database:  8482
  
Lambda     K      H
   0.322    0.136    0.459 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,204,194
Number of Sequences: 8482
Number of extensions: 54242
Number of successful extensions: 122
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 101
Number of HSP's gapped (non-prelim): 20
length of query: 139
length of database: 3,552,911
effective HSP length: 82
effective length of query: 57
effective length of database: 2,857,387
effective search space: 162871059
effective search space used: 162871059
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 51 (24.3 bits)





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