Neural Stem Cell

Over the years, enormous attention has focused on understanding the developmental origins of the nervous system. Scientists have postulated the existence of a single "stem" cell—a mother or queen of all cells—that is self-renewable and multipotent (i.e., capable of generating various committed progenitor cells and ultimately differentiating into mature cells).

A neural stem cell (NSC) is defined as a single cell with the ability to proliferate, exhibit self-maintenance or renewal over the lifetime of the organism, generate a large number of clonally related progeny, retain its multilineage potential over time, and produce new cells in response to injury or disease.

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