Angiotensinogen (AGT)

SNP Number Exon Position In Exon Confirmation Call Quality Heterozygosity Class Sample Detected Location In gene Amino Acid 1 Amino Acid 2 Type of Amino Acid Change Codon Position Codon 1 Codon 2 GenBank Accession # Allele 1 Allele 1 Frequency Allele 2 Allele 2 Frequency Flanking Sequence
CHAK00090 2 181 Confirmed Likely Rare U.S. White Coding Gln STOP Nonsynonymous 1 CAG TAG X15324 C 0.95 T 0.05 CCTGGCTGCAGGTGACCGGGTGTACATACACCCCTTCCACCTCGTCATCCACAATGAGAGTACCTGTGAG*AGCTGGCAAAGGCCAATGCCGGGAAGCCCAAAGACCCCACCTTCATACCTGCTCCAATTCAGGCCAAGAC
CHAK00091 2 354 Confirmed Likely Rare African Coding Ala Ala Synonymous 3 GCC GCT X15324 C 0.95 T 0.05 AGCTGGTGCTAGTCGCTGCAAAACTTGACACCGAAGACAAGTTGAGGGCCGCAATGGTCGGGATGCTGGC*AACTTCTTGGGCTTCCGTATATATGGCATGCACAGTGAGCTATGGGGCGTGGTCCATGGGGCCACCGTCC
CHAK00092 2 644 Confirmed Likely Low Both Coding Thr Met Nonsynonymous 2 ACG ATG X15324 C 0.9 T 0.1 CTGCAGGCTGTACAGGGCCTGCTAGTGGCCCAGGGCAGGGCTGATAGCCAGGCCCAGCTGCTGCTGTCCA*GGTGGTGGGCGTGTTCACAGCCCCAGGCCTGCACCTGAAGCAGCCGTTTGTGCAGGGCCTGGCTCTCTAT
CHAK00093 2 755 Confirmed Likely N/A African Coding Leu Arg Nonsynonymous 2 CTG CGG X15324 T N/A G N/A CAGCCGTTTGTGCAGGGCCTGGCTCTCTATACCCCTGTGGTCCTCCCACGCTCTCTGGACTTCACAGAAC*GGATGTTGCTGCTGAGAAGATTGACAGGTTCATGCAGGCTGTGACAGGATGGAAGACTGGCTGCTCCCTG
CHAK00094 2 827 Confirmed Likely Low African Coding Met Thr Nonsynonymous 2 ATG ACT X15324 T 0.1 C 0.9 GATGTTGCTGCTGAGAAGATTGACAGGTTCATGCAGGCTGTGACAGGATGGAAGACTGGCTGCTCCCTGA*GGGAGCCAGTGTGGACAGCACCCTGGCTTTCAACACCTACGTCCACTTCCAAGGTAAGGCAAACCTCTCT
CHAK00095 5 258 Confirmed Likely Rare African 3' UTR N/A N/A N/A 0 N/A N/A M24689 C 0.95 T 0.05 CCGCGTGGCCAACCCGCTGAGCACAGCATGAGGCCAGGGCCCCAGAACACAGTGCCTGGCAAGGCCTCTG*CCCTGGCCTTTGAGGCAAAGGCCAGCAGCAGATAACAACCCCGGACAAATCAGCGATGTGTCACCCCCAG
CHAK00096 5 376 Confirmed Likely Rare African 3' UTR N/A N/A N/A 0 N/A N/A M24689 C 0.95 G 0.05 AATCAGCGATGTGTCACCCCCAGTCTCCCACCTTTTCTTCTAATGAGTCGACTTTGAGCTGGAAAGCAGC*GTTTCTCCTTGGTCTAAGTGTGCTGCATGGAGTGAGCAGTAGAAGCCTGCAGCGGCACAAATGCACCTCC
CHAK00097 5 385 Confirmed Likely Rare African 3' UTR N/A N/A N/A 0 N/A N/A M24689 T 0.95 C 0.05 TGTGTCACCCCCAGTCTCCCACCTTTTCTTCTAATGAGTCGACTTTGAGCTGGAAAGCAGCCGTTTCTCC*TGGTCTAAGTGTGCTGCATGGAGTGAGCAGTAGAAGCCTGCAGCGGCACAAATGCACCTCCCAGTTTGCT
CHAK00098 5 641 Confirmed Likely Low African 3' UTR N/A N/A N/A 0 N/A N/A M24689 T 0.9 G 0.1 TTTTCAAGTTGAGAACAAAAATTGGGTTTTAAAATTAAAGTATACATTTTTGCATTGCCTTCGGTTTGTA*TTAGTGTCTTGAATGTAAGAACATGACCTCCGTGTAGTGTCTGTAATACCTTAGTTTTTTCCACAGATGC
CHAK00099 Promoter 101 Confirmed Likely Rare African Promoter N/A N/A N/A 0 N/A N/A X15323 G 0.95 C 0.05 AACAGCACATCTTTCAATGCCTGCATCCTGAAGGCATTTTGTTTGTGTCTTTCAATCTGGCTGTGCTATT*TTGGTGTTTAACAGTCTCCCCAGCTACACTGGAAACTTCCAGAAGGCACTTTTCACTTGCTTGTGTGTTT
CHAK00100 Promoter 173 Confirmed Certain Medium Both Promoter N/A N/A N/A 0 N/A N/A X15323 C 0.75 T 0.25 TGGTGTTTAACAGTCTCCCCAGCTACACTGGAAACTTCCAGAAGGCACTTTTCACTTGCTTGTGTGTTTT*CCCAGTGTCTATTAGAGGCCTTTGCACAGGGTAGGCTCTTTGGAGCAGCTGAAGGTCACACATCCCATGA
CHAK00101 Promoter 35 Confirmed Likely Rare U.S. White Promoter N/A N/A N/A 0 N/A N/A X15323 G 0.95 A 0.05 AGCAGGGTCAGAAGTGGCCCCCGTGTTGCCTAAGCAAGACTCTCCCCTGCCCTCTGCCCTCTGCACCTCC*GCCTGCATGTCCCTGTGGCCTCTTGGGGGTACATCTCCCGGGGCTGGGTCAGAAGGCCTGGGTGGTTGGC
CHAK00102 Promoter 160 Confirmed Likely Rare U.S. White Promoter N/A N/A N/A 0 N/A N/A X15323 G 0.95 A 0.05 GGCCTGGGTGGTTGGCCTCAGGCTGTCACACACCTAGGGAGATGCTCCCGTTTCTGGGAACCTTGGCCCC*ACTCCTGCAAACTTCGGTAAATGTGTAACTCGACCCTGCACCGGCTCACTCTGTTCAGCAGTGAAACTCT
CHAK00103 Promoter 203 Confirmed Certain Medium Both Promoter N/A N/A N/A 0 N/A N/A X15323 G 0.85 A 0.15 GCTCCCGTTTCTGGGAACCTTGGCCCCGACTCCTGCAAACTTCGGTAAATGTGTAACTCGACCCTGCACC*GCTCACTCTGTTCAGCAGTGAAACTCTGCATCGATCACTAAGACTTCCTGGAAGAGGTCCCAGCGTGAGT
CHAK00104 Promoter 144 Confirmed Certain Medium Both Promoter N/A N/A N/A 0 N/A N/A X15323 C 0.2 A 0.8 CCTCCTCTCCAGCCTGTGCACAGGCAGCCTGGGAACAGCTCCATCCCCACCCCTCAGCTATAAATAGGGC*TCGTGACCCGGCCAGGGGAAGAAGCTGCCGTTGTTCTGGGTACTACAGCAGAAGGTAAGCCGGGGGCCCC
CHAK00105 Promoter 158 Confirmed Likely High U.S. White Promoter N/A N/A N/A 0 N/A N/A X15323 A 0.7 G 0.3 TGTGCACAGGCAGCCTGGGAACAGCTCCATCCCCACCCCTCAGCTATAAATAGGGCCTCGTGACCCGGCC*GGGGAAGAAGCTGCCGTTGTTCTGGGTACTACAGCAGAAGGTAAGCCGGGGGCCCCCTCA
CHAK00106 Promoter 173 Confirmed Likely Rare U.S. White Promoter N/A N/A N/A 0 N/A N/A X15323 C 0.95 T 0.05 TGGGAACAGCTCCATCCCCACCCCTCAGCTATAAATAGGGCCTCGTGACCCGGCCAGGGGAAGAAGCTGC*GTTGTTCTGGGTACTACAGCAGAAGGTAAGCCGGGGGCCCCCTCA 
Please e-mail any questions or suggestions to Michael A. Choma or Marc Halushka.