Aldehyde Reductase (ALDR1)

SNP Number Exon Position In Exon Confirmation Call Quality Heterozygosity Class Sample Detected Location In gene Amino Acid 1 Amino Acid 2 Type of Amino Acid Change Codon Position Codon 1 Codon 2 GenBank Accession # Allele 1 Allele 1 Frequency Allele 2 Allele 2 Frequency Flanking Sequence
CHAK00107 1 71 Confirmed Certain High African Promoter N/A N/A N/A 0 N/A N/A M59856 C 0.35 G 0.65 GCGCGCCAACCGCAGGCGCCCTTTCTGCCGACCTCACGGGCTATTTAAAGGTACGCGCCG*GGCCAAGGCCGCACCGTACTGGGCGGGGGTCTGGGGAGCGCAGCAGCCATGGCAAGCCGT
CHAK00108 1 162 Confirmed Likely Medium U.S. White Coding Ile Phe Nonsynonymous 1 ATC TTC M59856 A 0.9 T 0.1 CTGGGGAGCGCAGCAGCCATGGCAAGCCGTCTCCTGCTCAACAACGGCGCCAAGATGCCC*TCCTGGGGTTGGGTACCTGGAAGGTAGGTGCTCGTGGGGGCGCGGGCCCGGGGCTCGCCT
CHAK00109 10 150 Not Confirmed Likely Rare African 3' UTR N/A N/A N/A 0 N/A N/A M59783 T 0.95 G 0.05 CGTCCCCAAGTGACCTATACCTGTGTTTCTTGCCTCATTTTTTTCCTTGCAAATGTAGTA*GGCCTGTGTCACTCAGCAGTGGGACAGCAACCTGTAGAGTGGCCAGCGAGGGCGTGTCTA
CHAK00110 2 88 Not Confirmed Likely Rare African Coding His Leu Nonsynonymous 2 CAC CTC M59783 A 0.95 T 0.05 AGTCCCCTCCAGGGCAGGTGACTGAGGCCGTGAAGGTGGCCATTGACGTCGGGTACCGCC*CATCGACTGTGCCCATGTGTACCAGAATGAGAATGAGGTGGGGGTGGCCATTCAGGAGAA
CHAK00111 2 180 Not Confirmed Likely Rare U.S. White Coding Leu Val Nonsynonymous 1 CTC GTC M59783 C 0.95 G 0.05 AATGAGGTGGGGGTGGCCATTCAGGAGAAGCTCAGGGAGCAGGTGGTGAAGCGTGAGGAG*TCTTCATCGTCAGCAAGGTATCGTTCCGCGGTGGGGCTGGAAGGGGCTCTCGGTCCCATC
CHAK00112 2 204 Not Confirmed Likely Rare U.S. White Intron N/A N/A N/A 0 N/A N/A M59783 T 0.95 G 0.05 GAGAAGCTCAGGGAGCAGGTGGTGAAGCGTGAGGAGCTCTTCATCGTCAGCAAGGTATCG*TCCGCGGTGGGGCTGGAAGGGGCTCTCGGTCCCATCATCTGTTGGTGCATCAGCCCAAAG
CHAK00113 3 28 Not Confirmed Likely Rare African Intron N/A N/A N/A 0 N/A N/A M59783 A 0.95 T 0.05 TTTCCAGCCAGGAAGCTGCCTTGTGGCTGGCAATGATGACATGTGCCCTCTCGCTGGCTT*GCTGTGGTGCACGTACCATGAGAAGGGCCTGGTGAAAGGAGCCTGCCAGAAGACACTCAG
CHAK00114 4 101 Not Confirmed Likely Rare African Coding Thr Thr Synonymous 3 ACG ACA M59783 G 0.95 A 0.05 ATTTTTCCCATTGGATGAGTCGGGCAATGTGGTTCCCAGTGACACCAACATTCTGGACAC*TGGGCGGTAAGACAGCCCCTGGTTGGACCTTGTTTTCGTGACTGGTTCCCTCTTCTTCTT
CHAK00115 6 87 Not Confirmed Likely Rare U.S. White Coding Gly Ser Nonsynonymous 1 GGC AGC M59783 G 0.95 A 0.05 CAGATTGAGTGCCACCCATATCTCACTCAGGAGAAGTTAATCCAGTACTGCCAGTCCAAA*GCATCGTGGTGACCGCCTACAGCCCCCTCGGCTCTCCTGACAGGCCCTGGTGAGCTTCCC
CHAK00116 9 67 Not Confirmed Likely Rare African Coding Thr Ile Nonsynonymous 2 ACC ATC M59783 C 0.95 T 0.05 TGGATTTTTTGTTTGTTTTTTAGGTCTTTGACTTTGAACTGAGCAGCCAGGATATGACCA*CTTACTCAGCTACAACAGGAACTGGAGGGTCTGTGCCTTGTTGAGGTGAGTGAGCCCCAG 
Please e-mail any questions or suggestions to Michael A. Choma or Marc Halushka.