Apolipoprotein A4 (APOA4)

SNP Number Exon Position In Exon Confirmation Call Quality Heterozygosity Class Sample Detected Location In gene Amino Acid 1 Amino Acid 2 Type of Amino Acid Change Codon Position Codon 1 Codon 2 GenBank Accession # Allele 1 Allele 1 Frequency Allele 2 Allele 2 Frequency Flanking Sequence
CHAK00143 N/A 350 Not Confirmed Likely Low African Promoter N/A N/A N/A 0 N/A N/A J02758 G 0.9 A 0.1 GATGTGGACTTTGCCCCCCATGAGCCCGGCACAAACCCGAGAGGCCGCCAGCAGGGCCTC*AGGCATCAGTCCCGGGCTCATGGGCTCCCTGAGGTGTTTCTCCTACTGTTTTCCGTTCCC
CHAK00144 N/A 637 Not Confirmed Likely Rare U.S. White Promoter N/A N/A N/A 0 N/A N/A J02758 G 0.95 C 0.05 CGTGGAGTCACACTGAGGAAGGAGGAGGGGAGGGCAGCCAGGGGGGTGGCGATAGGGAGA*AGTTTAAATGTCTGGCTGGCTCTGAGCTTCAGTCAGTTCCCACTGCAGCGCAGGTGAGCT
CHAK00145 N/A 687 Not Confirmed Likely Rare African Promoter N/A N/A N/A 0 N/A N/A J02758 G 0.95 A 0.05 GATAGGGAGAGAGTTTAAATGTCTGGCTGGCTCTGAGCTTCAGTCAGTTCCCACTGCAGC*CAGGTGAGCTCTCCTGAGGACCTCTCTGTCAGCTCCCCTGATTGTAGGGAGGATCCAGTG
CHAK00146 N/A 1228 Not Confirmed Likely High Both Coding Thr Thr Synonymous 3 ACA ACG J02758 A 0.65 G 0.35 AATTGCTCTCTGTTACCACCCAGGAGCCAGGGCTGAGGTCAGTGCTGACCAGGTGGCCAC*GTGATGTGGGACTACTTCAGCCAGCTGAGCAACAATGCCAAGGAGGCCGTGGAACATCTC
CHAK00147 N/A 1338 Not Confirmed Certain Rare U.S. White Intron N/A N/A N/A 0 N/A N/A J02758 T 0.05 C 0.95 TGGAACATCTCCAGAAATCTGAACTCACCCAGCAACTCAAGTAAGAGGGACTACAGTGTG*GGTGGTGACGGGGAATTCTTAAAGGCCATGCAATGTACTGGCAAGGGTTGAGCTTAGAGA
CHAK00148 N/A 1479 Not Confirmed Certain Rare African Intron N/A N/A N/A 0 N/A N/A J02758 C 0.95 T 0.05 TACCCACTGCCCTGCCACTAACTGGCCGGGCCTCTGAACCTAGGATCCACATATGTAAAC*GGAAGTTTGGACCGAATAATCCCTGCCATGTCCTTTTGCTTTGACGTTCTAGAGTTTGAC
CHAK00149 N/A 1529 Not Confirmed Likely Low Both Intron N/A N/A N/A 0 N/A N/A J02758 T 0.9 C 0.1 ATATGTAAACCGGAAGTTTGGACCGAATAATCCCTGCCATGTCCTTTTGCTTTGACGTTC*AGAGTTTGACAAATGGCCACATCCTATCATTCAGGCTCATGGAAGAGAGGGAGGGAGGAA
CHAK00150 N/A 1597 Not Confirmed Certain High African Intron N/A N/A N/A 0 N/A N/A J02758 T 0.65 C 0.35 GACAAATGGCCACATCCTATCATTCAGGCTCATGGAAGAGAGGGAGGGAGGAAAATGTCA*GTGAGCTGATTTCTAATACGTTTCAGAAAGACAGGCCCCAGTGGAATCAAGGGGAGGGAG
CHAK00151 N/A 1617 Not Confirmed Likely Rare African Intron N/A N/A N/A 0 N/A N/A J02758 G 0.95 A 0.05 CATTCAGGCTCATGGAAGAGAGGGAGGGAGGAAAATGTCATGTGAGCTGATTTCTAATAC*TTTCAGAAAGACAGGCCCCAGTGGAATCAAGGGGAGGGAGGTGGGAATATTTGGGAGGCC
CHAK00152 N/A 1879 Not Confirmed Likely Low African Intron N/A N/A N/A 0 N/A N/A J02758 C 0.95 G 0.05 CAGACAAGGAGGGGAAAGCAAACTGCTGGAGGTGACATGGTGGGTAGATTCTGAGACAAA*TATGTGGGAGATCCTGAGATAGAAATTCAGCATCGTAACTTAGTCTGTGACACCCATCCT
CHAK00153 N/A 1961 Not Confirmed Likely Rare African Intron N/A N/A N/A 0 N/A N/A J02758 G 0.95 A 0.05 GAAATTCAGCATCGTAACTTAGTCTGTGACACCCATCCTCTCCAATCTGCACCACCATAG*GAGGGTGAACTCGGTACCTCTGAGCACTCACCTGTCTTAGCACGTGTGCATAAGGCGAGT
CHAK00154 N/A 1998 Not Confirmed Likely High Both Intron N/A N/A N/A 0 N/A N/A J02758 T 0.65 C 0.35 CTCTCCAATCTGCACCACCATAGGGAGGGTGAACTCGGTACCTCTGAGCACTCACCTGTC*TAGCACGTGTGCATAAGGCGAGTGGTATACAAGCAGACAAAGTCTTGCCGTGTAAATGCC
CHAK00155 N/A 2134 Not Confirmed Certain High African Coding Tyr Tyr Synonymous 3 TAC TAT J02758 C 0.7 T 0.3 TCCTTGTGCCCTTCCCCACAGTGCCCTCTTCCAGGACAAACTTGGAGAAGTGAACACTTA*GCAGGTGACCTGCAGAAGAAGCTGGTGCCCTTTGCCACCGAGCTGCATGAACGCCTGGCC
CHAK00156 N/A 2138 Not Confirmed Likely Rare African Coding Gly Ser Nonsynonymous 1 GGT AGT J02758 G 0.95 A 0.05 TGTGCCCTTCCCCACAGTGCCCTCTTCCAGGACAAACTTGGAGAAGTGAACACTTACGCA*GTGACCTGCAGAAGAAGCTGGTGCCCTTTGCCACCGAGCTGCATGAACGCCTGGCCAAGG
CHAK00157 N/A 2140 Not Confirmed Likely Rare U.S. White Coding Gly Gly Synonymous 3 GGT GGC J02758 T 0.95 C 0.05 TGCCCTTCCCCACAGTGCCCTCTTCCAGGACAAACTTGGAGAAGTGAACACTTACGCAGG*GACCTGCAGAAGAAGCTGGTGCCCTTTGCCACCGAGCTGCATGAACGCCTGGCCAAGGAC
CHAK00158 N/A 2358 Not Confirmed Likely Medium Both Coding Asn Ser Nonsynonymous 2 AAC AGC J02758 A 0.85 G 0.15 ACCTGCGAGAGCTTCAGCAGCGCCTGGAGCCCTACGCGGACCAGCTGCGCACCCAGGTCA*CACGCAGGCCGAGCAGCTGCGGCGCCAGCTGACCCCCTACGCACAGCGCATGGAGAGAGT
CHAK00159 N/A 2698 Not Confirmed Likely Low African Coding Ala Ala Synonymous 3 GCC GCT J02758 C 0.95 T 0.05 CCTGACCTTCCAGATGAAGAAGAACGCCGAGGAGCTCAAGGCCAGGATCTCGGCCAGTGC*GAGGAGCTGCGGCAGAGGCTGGCGCCCTTGGCCGAGGACGTGCGTGGCAACCTGAGGGGC
CHAK00160 N/A 2764 Not Confirmed Likely Low African Coding Thr Thr Synonymous 3 ACC ACT J02758 C 0.9 T 0.1 GCTGCGGCAGAGGCTGGCGCCCTTGGCCGAGGACGTGCGTGGCAACCTGAGGGGCAACAC*GAGGGGCTGCAGAAGTCACTGGCAGAGCTGGGTGGGCACCTGGACCAGCAGGTGGAGGAG
CHAK00161 N/A 2806 Not Confirmed Likely Rare African Coding Leu Leu Synonymous 3 CTG CTA J02758 G 0.95 A 0.05 CAACCTGAGGGGCAACACCGAGGGGCTGCAGAAGTCACTGGCAGAGCTGGGTGGGCACCT*GACCAGCAGGTGGAGGAGTTCCGACGCCGGGTGGAGCCCTACGGGGAAAACTTCAACAAA
CHAK00162 N/A 2837 Not Confirmed Likely Rare African Coding Val Leu Nonsynonymous 1 GTG CTG J02758 G 0.95 C 0.05 AAGTCACTGGCAGAGCTGGGTGGGCACCTGGACCAGCAGGTGGAGGAGTTCCGACGCCGG*TGGAGCCCTACGGGGAAAACTTCAACAAAGCCCTGGTGCAGCAGATGGAACAGCTCAGGA
CHAK00163 N/A 2926 Not Confirmed Certain Medium African Coding Val Val Synonymous 3 GTG GTT J02758 G 0.85 T 0.15 AGCCCTGGTGCAGCAGATGGAACAGCTCAGGACGAAACTGGGCCCCCATGCGGGGGACGT*GAAGGCCACTTGAGCTTCCTGGAGAAGGACCTGAGGGACAAGGTCAACTCCTTCTTCAGC
CHAK00164 N/A 3058 Confirmed Certain Medium U.S. White Coding His Gln Nonsynonymous 3 CAT CAG J02758 T 0.2 G 0.8 GAAAGAGAGCCAGGACAAGACTCTCTCCCTCCCTGAGCTGGAGCAACAGCAGGAACAGCA*CAGGAGCAGCAGCAGGAGCAGGTGCAGATGCTGGCCCCTTTGGAGAGCTGAGCTGCCCCT 
Please e-mail any questions or suggestions to Michael A. Choma or Marc Halushka.