Apolipoprotein C4 (APOC4)

SNP Number Exon Position In Exon Confirmation Call Quality Heterozygosity Class Sample Detected Location In gene Amino Acid 1 Amino Acid 2 Type of Amino Acid Change Codon Position Codon 1 Codon 2 GenBank Accession # Allele 1 Allele 1 Frequency Allele 2 Allele 2 Frequency Flanking Sequence
CHAK00202 N/A 483 Not Confirmed Likely Rare U.S. White Intron N/A N/A N/A 0 N/A N/A U32576 T 0.95 G 0.05 TGGCGTGCGTATGCATGTGCGTGTCGGGGAGTGTGTGTGTCGGTGGCTGAGAGTGAAGTG*GAATGTCACATTGGTACAAACTGGGATCATCTGTGTGTGTGCACGTGCGTGCGTGGAAGT
CHAK00203 N/A 931 Not Confirmed Likely Rare African Intron N/A N/A N/A 0 N/A N/A U32576 A 0.95 G 0.05 TGCCTGGCTAATTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTTACCCAGGCTGGAGTGC*GTGGCGTGATCTTGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCT
CHAK00204 N/A 968 Not Confirmed Likely Medium Both Intron N/A N/A N/A 0 N/A N/A U32576 C 0.75 T 0.25 CTCTGTTACCCAGGCTGGAGTGCAGTGGCGTGATCTTGGCTCACTGCAAGCTCCGCCTCC*GGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGAGCCCACCA
CHAK00205 N/A 1150 Not Confirmed Likely High U.S. White Intron N/A N/A N/A 0 N/A N/A U32576 T 0.4 C 0.6 TGGTCTCCATATCCTGACCTCGTGATCCGCCTGCCTCGGCCTTCCAAAGTGCTAGGATTA*AGGCGTGAGCCACTGCGCCTGGCCAATGCCTGGCTAATTTTTTTATATTTTTGGTAGAGA
CHAK00206 N/A 1246 Not Confirmed Likely Medium U.S. White Intron N/A N/A N/A 0 N/A N/A U32576 A 0.2 C 0.8 AATTTTTTTATATTTTTGGTAGAGACAGGGTTTTGCCATGTTGCCCAGGCTGGTCTTGAA*TCCTGACCTCAGGTGATCCGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGA
CHAK00207 N/A 1281 Not Confirmed Likely Medium African Intron N/A N/A N/A 0 N/A N/A U32576 C 0.9 T 0.1 CCATGTTGCCCAGGCTGGTCTTGAAATCCTGACCTCAGGTGATCCGCCCGCCTTGGCCTC*CAAAGTGCTGGGATTACAGGCATGAGCCACCACGCCCGGCCATGTACTTTATGTTAAAAT
CHAK00209 N/A 1313 Not Confirmed Likely High U.S. White Intron N/A N/A N/A 0 N/A N/A U32576 A 0.5 G 0.5 CCTCAGGTGATCCGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACC*CGCCCGGCCATGTACTTTATGTTAAAATGGGATCATATTCTAGATCAGCATTATCCAGTA
CHAK00210 N/A 1406 Not Confirmed Likely Low U.S. White Intron N/A N/A N/A 0 N/A N/A U32576 G 0.9 A 0.1 TCATATTCTAGATCAGCATTATCCAGTAGAAATTTAAATTTTTAATACAGGGCCAGGCAC*GTGGCTCATGCCTGTAATCCCAGCACTTTCGGAGGCCGAGGCGGGTGGATCGCAAGGTCA
CHAK00211 N/A 1446 Not Confirmed Likely Low U.S. White Intron N/A N/A N/A 0 N/A N/A U32576 G 0.9 A 0.1 TTTAATACAGGGCCAGGCACGGTGGCTCATGCCTGTAATCCCAGCACTTTCGGAGGCCGA*GCGGGTGGATCGCAAGGTCAGGAGATTTGAGATCATCCTGGCTAACAGATGGGTAAAAAC
CHAK00212 N/A 1587 Not Confirmed Likely Medium Both Intron N/A N/A N/A 0 N/A N/A U32576 C 0.2 A 0.8 AAAAATTAGCCATGCATGGTGGCATGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGC*GGAGAATCACTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCGAGATCGCGCCACTGCAT
CHAK00213 N/A 1782 Not Confirmed Likely Rare African Intron N/A N/A N/A 0 N/A N/A U32576 G 0.95 C 0.05 GGCACCATTCCATGTGCATCGTATGTAGTAACTCTTAATTCTCACGATAACCCTGAGGTA*ATATTATTACCCCGTTCTACAAAAGGAGAAACAGTCCTGGGGAGACAGGATAAGTCACCG
CHAK00214 N/A 1794 Not Confirmed Likely Low African Intron N/A N/A N/A 0 N/A N/A U32576 C 0.95 T 0.05 TGTGCATCGTATGTAGTAACTCTTAATTCTCACGATAACCCTGAGGTAGATATTATTACC*CGTTCTACAAAAGGAGAAACAGTCCTGGGGAGACAGGATAAGTCACCGGCCAAGGCACAC
CHAK00215 N/A 1842 Not Confirmed Likely Rare African Intron N/A N/A N/A 0 N/A N/A U32576 G 0.95 A 0.05 GATATTATTACCCCGTTCTACAAAAGGAGAAACAGTCCTGGGGAGACAGGATAAGTCACC*GCCAAGGCACACAGCTAGCTACATGTGGCCCCCGCGTGACGGCTGGTCTCTGTAGGCGAG
CHAK00216 N/A 1858 Not Confirmed Certain Medium Both Intron N/A N/A N/A 0 N/A N/A U32576 T 0.25 C 0.75 TCTACAAAAGGAGAAACAGTCCTGGGGAGACAGGATAAGTCACCGGCCAAGGCACACAGC*AGCTACATGTGGCCCCCGCGTGACGGCTGGTCTCTGTAGGCGAGGCTTTGTCCAGATGCG
CHAK00217 N/A 1875 Not Confirmed Likely Low Both Intron N/A N/A N/A 0 N/A N/A U32576 C 0.95 T 0.05 AGTCCTGGGGAGACAGGATAAGTCACCGGCCAAGGCACACAGCTAGCTACATGTGGCCCC*GCGTGACGGCTGGTCTCTGTAGGCGAGGCTTTGTCCAGATGCGTGGGTAGAAGGTCTGGC
CHAK00218 N/A 2206 Not Confirmed Likely Low African Intron N/A N/A N/A 0 N/A N/A U32576 A 0.9 G 0.1 GGAACCACAGGCAGACAGGGTGACAGGAGGGACTACTGACACAAGGTGAAGAGATGGCCC*GCCGGACGGGGTGGCTCACATCTGTAATCCCAGCATTTTGGGAGCCCGAGGTGGGTGGAT
CHAK00219 N/A 2237 Not Confirmed Likely Low U.S. White Intron N/A N/A N/A 0 N/A N/A U32576 C 0.9 T 0.1 ACTACTGACACAAGGTGAAGAGATGGCCCAGCCGGACGGGGTGGCTCACATCTGTAATCC*AGCATTTTGGGAGCCCGAGGTGGGTGGATCACTTGAGGTCAGGAGTTCGAGGCCCCAACA
CHAK00220 N/A 2276 Not Confirmed Likely High Both Intron N/A N/A N/A 0 N/A N/A U32576 T 0.7 C 0.3 GGTGGCTCACATCTGTAATCCCAGCATTTTGGGAGCCCGAGGTGGGTGGATCACTTGAGG*CAGGAGTTCGAGGCCCCAACATGGCAAAACCCCATCTCTTCTAAAAATACAAAAATTAGC
CHAK00221 N/A 2345 Not Confirmed Likely High U.S. White Intron N/A N/A N/A 0 N/A N/A U32576 A 0.7 G 0.3 CGAGGCCCCAACATGGCAAAACCCCATCTCTTCTAAAAATACAAAAATTAGCCGGGCATG*TGGCAGATGCCTGTAATCCCTGCTACTCGGGAGGCTGAGGCAGGAAAATTGCCTGAATCC
CHAK00222 N/A 2366 Not Confirmed Likely High U.S. White Intron N/A N/A N/A 0 N/A N/A U32576 T 0.55 A 0.45 CCCCATCTCTTCTAAAAATACAAAAATTAGCCGGGCATGATGGCAGATGCCTGTAATCCC*GCTACTCGGGAGGCTGAGGCAGGAAAATTGCCTGAATCCAGGAGGTGGAGGTTGCAATGA
CHAK00223 N/A 2767 Not Confirmed Likely Rare African Coding Trp Stop Nonsynonymous 3 TGG TGA U32576 G 0.95 A 0.05 CCAGCCAGAGGCCCAGGAAGGAACCCTGAGCCCCCCACCAAAGCTAAAGATGAGTCGCTG*AGCCTGGTGAGGGGCAGGATGAAGGAGCTGCTGGAGACAGTGGTGAACAGGACCAGAGAC
CHAK00224 N/A 3027 Not Confirmed Likely Rare African Intron N/A N/A N/A 0 N/A N/A U32576 G 0.95 A 0.05 GTCTGGGAGGAGTGGAGGGTTAGAGCTGAGAGCAGGAACTCCTAGGTCACAGAGAGGAGC*GATAAATGGGGCAGAGAACACCTGGGGAGAGCTGGGGCCTCCACTGTGATGTCCTCTCTC
CHAK00225 N/A 3078 Not Confirmed Likely Rare U.S. White Intron N/A N/A N/A 0 N/A N/A U32576 G 0.95 C 0.05 GAGAGGAGCGGATAAATGGGGCAGAGAACACCTGGGGAGAGCTGGGGCCTCCACTGTGAT*TCCTCTCTCCTGTAGGAGCCCGAGCACCTTCCGGGGCTTCATGCAGACCTACTATGACGA
CHAK00226 N/A 3162 Confirmed Certain High Both Coding Leu Arg Nonsynonymous 2 CTC CGC U32576 T 0.5 G 0.5 GCACCTTCCGGGGCTTCATGCAGACCTACTATGACGACCACCTGAGGGACCTGGGTCCGC*CACCAAGGCCTGGTTCCTCGAATCCAAAGACAGCCTCTTGAAGAAGACCCACAGCCTGTG
CHAK00227 N/A 3252 Not Confirmed Likely Rare U.S. White Coding Gln Leu Nonsynonymous 2 CAG CTG U32576 A 0.95 T 0.05 ACAGCCTCTTGAAGAAGACCCACAGCCTGTGCCCCAGGCTTGTCTGTGGGGACAAGGACC*GGGTTAAAATGTTCATAAAAGCCAGGTGTGGTTGTGGCGGGTGCCTGTAGTCCCAGCTAC 
Please e-mail any questions or suggestions to Michael A. Choma or Marc Halushka.