Angiotensin Converting Enzyme (DCP1)

SNP Number Exon Position In Exon Confirmation Call Quality Heterozygosity Class Sample Detected Location In gene Amino Acid 1 Amino Acid 2 Type of Amino Acid Change Codon Position Codon 1 Codon 2 GenBank Accession # Allele 1 Allele 1 Frequency Allele 2 Allele 2 Frequency Flanking Sequence
CHAK00015 13 138 Confirmed Likely High Both Coding Pro Pro Synonymous 3 CCC CCT M73275, M26657 C 0.7 T 0.3 GTTGGGCTACTGCAGGACTTCCCAGCCTCCTCTTCCTGCTGCTCTGCTACGGGCACCCTCTGCTGGTCCC*AGCCAGGAGGCATCCCAACAGGTGACAGTCACCCATGGGACAAGCAGCCAGGCAACAACCAGCAGCCAGA
CHAK00016 13 151 Confirmed Likely Medium African Coding Ser Pro Nonsynonymous 1 TCT CCT M73275, M26657 T 0.75 C 0.25 AGGACTTCCCAGCCTCCTCTTCCTGCTGCTCTGCTACGGGCACCCTCTGCTGGTCCCCAGCCAGGAGGCA*CCCAACAGGTGACAGTCACCCATGGGACAAGCAGCCAGGCAACAACCAGCAGCCAGACAACCACCCACCA
CHAK00017 13 202 Confirmed Certain Medium African Coding Ser Gly Nonsynonymous 1 AGC GGC M73275, M26657 A 0.75 G 0.25 GGTCCCCAGCCAGGAGGCATCCCAACAGGTGACAGTCACCCATGGGACAAGCAGCCAGGCAACAACCAGC*GCCAGACAACCACCCACCAGGCGACGGCCCACCAGACATCAGCCCAGAGCCCAAACCTGGTGACTGATGA
CHAK00018 15 144 Confirmed Certain Medium U.S. White Coding Ala Ala Synonymous 3 GCG GCA J04144 G 0.8 A 0.2 ATGTGAACCAGTTGCAGAACACCACTATCAAGCGGATCATAAAGAAGGTTCAGGACCTAGAACGGGCAGC*CTGCCTGCCCAGGAGCTGGAGGAGTACAACAAGATCCTGTTGGATATGGAAACCACCTACAGCGTGGC
CHAK00019 17 19 Confirmed Likely High Both Intron N/A N/A N/A 0 N/A N/A J04144, A28005 C 0.55 A 0.45 CTCTGAGCTCCCCTTACAAGCAGAGGTGAGCTAAGGGCTGGAGCTCAAGCCATTCAA*CCCCTACCAGATCTGACGAATGTGATGGCCACATCCCGGAAATATGAAGACCTGTTATGGGCATGGGAGG
CHAK00020 17 52 Confirmed Certain High Both Coding Thr Thr Synonymous 3 ACA ACG J04144, A28005 A 0.5 G 0.5 CAGAGGTGAGCTAAGGGCTGGAGCTCAAGCCATTCAACCCCCTACCAGATCTGACGAATGTGATGGCCAC*TCCCGGAAATATGAAGACCTGTTATGGGCATGGGAGGGCTGGCGAGACAAGGCGGGGAGAGCCATCCTCC
CHAK00021 18 130 Confirmed Likely Rare Both Coding Leu Leu Synonymous 3 CTC CTG J04144, A28005 C 0.95 G 0.05 CTATGTACGAGACACCATCCCTGGAGCAAGACCTGGAGCGGCTCTTCCAGGAGCTGCAGCCACTCTACCT*AACCTGCATGCCTACGTGCGCCGGGCCCTGCACCGTCACTACGGGGCCCAGCACATCAACCTGGAGGGGC
CHAK00022 21 150 Confirmed Likely Rare African Coding Ile Thr Nonsynonymous 2 ATT ACT J04144 T 0.95 C 0.05 TATTTCATGCAGTACAAAGACTTACCTGTGGCCTTGAGGGAGGGTGCCAACCCCGGCTTCCATGAGGCCA*TGGGGACGTGCTAGCCCTCTCAGTGTCTACGCCCAAGCACCTGCACAGTCTCAACCTGCTGAGCAGTGAG
CHAK00023 22 19 Confirmed Likely Rare U.S. White Coding Phe Val Nonsynonymous 1 TTT GTT J04144 T 0.95 G 0.05 CTGCACAGTCTCAACCTGCTGAGCAGTGAGGGTGGCAGCGACGAGCATGACATCAAC*TTCTGATGAAGATGGCCCTTGACAAGATCGCCTTTATCCCCTTCAGCTACCTCGTCGATCAGTGGCGCTG
CHAK00024 24 16 Confirmed Likely High Both Coding Phe Phe Synonymous 3 TTT TTC J04144 T 0.45 C 0.55 TGACCCAGGGGCCAAGTTCCACATTCCTTCTAGCGTGCCTTACATCAGGTACTT*GTCAGCTTCATCATCCAGTTCCAGTTCCACGAGGCACTGTGCCAGGCAGCTGGCCACACGGGCCCCCTGC
CHAK00025 24 118 Confirmed Likely Rare African Coding Ala Ala Synonymous 3 GCC GCT J04144 C 0.95 T 0.05 AGGCACTGTGCCAGGCAGCTGGCCACACGGGCCCCCTGCACAAGTGTGACATCTACCAGTCCAAGGAGGC*GGGCAGCGCCTGGCGACCGCCATGAAGCTGGGCTTCAGTAGGCCGTGGCCGGAAGCC
CHAK00026 26 154 Confirmed Likely Rare African Coding Arg Gln Nonsynonymous 2 CGG CAG J04144, X94360 G 0.95 A 0.05 CGCGTGGGCCAGTGGCTGCTGCTCTTCCTGGGCATCGCCCTGCTGGTAGCCACCCTGGGCCTCAGCCAGC*GCTCTTCAGCATCCGCCACCGCAGCCTCCACCGGCACTCCCACGGGCCCCAGTTCGGCTCCGAGGTGGAG
CHAK00027 26 174 Confirmed Certain Low African Coding Arg Ser Nonsynonymous 1 CGC AGC J04144, X94360 C 0.9 A 0.1 GCTCTTCCTGGGCATCGCCCTGCTGGTAGCCACCCTGGGCCTCAGCCAGCGGCTCTTCAGCATCCGCCAC*GCAGCCTCCACCGGCACTCCCACGGGCCCCAGTTCGGCTCCGAGGTGGAGCTGAGACACTCCTGAGGTGA
CHAK00028 26 205 Confirmed Likely N/A U.S. White Coding Gln Pro Nonsynonymous 2 CAG CCG J04144, X94360 A N/A C N/A ACCCTGGGCCTCAGCCAGCGGCTCTTCAGCATCCGCCACCGCAGCCTCCACCGGCACTCCCACGGGCCCC*GTTCGGCTCCGAGGTGGAGCTGAGACACTCCTGAGGTGACCCGGCTGGGTCGGCCCTGCCCAAGGGCCTC
CHAK00029 26 224 Confirmed Likely Low U.S. White Coding Glu Glu Synonymous 3 GAG GAA J04144, X94360 G 0.95 A 0.05 GGCTCTTCAGCATCCGCCACCGCAGCCTCCACCGGCACTCCCACGGGCCCCAGTTCGGCTCCGAGGTGGA*CTGAGACACTCCTGAGGTGACCCGGCTGGGTCGGCCCTGCCCAAGGGCCTCCCACCAGAGACTGGGATGG
CHAK00910 Promoter -5491 AmJHumGenet 58:1268-1278,1996 N/A N/A Literature Search Promoter N/A N/A N/A 0 N/A N/A N/A T N/A C N/A CAGAACATTTCACTACCCCTAAAAGAAACCCCATACCACAGATTCCGATGCCGCCGGGAGCCCTG*CATGCCATGTCACATATATTATAGTATATATATGCCCAGCCATGGTCAACCCACCGTGTTCTTTG
CHAK00911 Promoter -5466 AmJHumGenet 58:1268-1278,1996 N/A N/A Literature Search Promoter N/A N/A N/A 0 N/A N/A N/A A N/A C N/A ATACCACAGATTCCGATGCCGCCGGGAGCCCTGTCATGCCATGTCACATATATTATAGTATAT*TATGCCCAGCCATGGTCAACCCACCGTGTTCTTTGACATCACCATCAACAGCAAGCCCTTGGGCC
CHAK00912 Promoter -3892 AmJHumGenet 58:1268-1278,1996 N/A N/A Literature Search Promoter N/A N/A N/A 0 N/A N/A N/A T N/A C N/A TCTTCAATTTCAGGCATCCATTGAGAGTCTTGGAATGTACCCACTGAGGATAAGGGGGGG*TGCTGTACATACTTTGCAAATATCTTCTCTCATCCCATGGGTTGTCTTTTCATTTTCTTTCTTT
CHAK00913 Promoter -240 AmJHumGenet 58:1268-1278,1996 N/A N/A Literature Search Promoter N/A N/A N/A 0 N/A N/A N/A T N/A A N/A GCTGCGCGGCCGCACGGTGGGCAGGCTCGGGTGTTCCGGCAAACTGCCGGGTCCCCATCTTC*AAAGAGAGGAGGCCCTTTCTCCAGCTTCCTCTGCGGGAGCCCGACCCAGCCCCATCCCGCC
CHAK00914 Promoter -93 AmJHumGenet 58:1268-1278,1996 N/A N/A Literature Search Promoter N/A N/A N/A 0 N/A N/A N/A T N/A C N/A CCGGCCCGCGCCCCTGCCCGGGGCGGGCCAGGAACCTCGGCCCGCGCCGCTGGGGACT*TGGAGCGGAGGAGGAAGCGCGGCGGGGCGGGGGCGGGGGTGTGTCGGGTTTTATAACC
CHAK00915 8 106 WIAF-1325 N/A N/A Literature Search Coding Pro Pro Synonymous 3 CCC CCT J04144 C N/A T N/A GATCAAGCAGTGCACACGGGTCACGATGGACCAGCTCTCCACAGTGCACCATGAGATGGGCCATATACAGTACTACCTGCAGTACAAGGATCTGCC*GTCTCCCTGCGTCGGGGGGCCAACCCCGGCTTCCATGAGGCCATTGGGGACGTGCTGGCGCTCTCGGTCTCCACTCCTGAACATCTGCACAAAATCGGCCTGC 
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