Welcome to the on-line resource for Hypertension Candidate Genes. Below is a list of 150 candidate genes. Each gene is clickable and will open to a new web page showing all available data collected. Available data includes map location and genetic interval, OMIM number, sequence data, and expression data for each gene. If you would like a tab-delimited text file of this information, click here.


List By Gene Symbols | List By Gene Function | GIST
11-Beta Hydroxysteroid Dehydrogenase B1 (HSD11B1)
11-Beta Hydroxysteroid Dehydrogenase B2 (HSD11B2)
17 Alpha Hydroxylase (CYP17)
Adducin - alpha (ADD1)
Adducin - beta (ADD2)
Adducin - gamma (ADD3)
Adenosine A1 Receptor (ADORA1)
Adenosine A2A Receptor (ADORA2A)
Adrenomedullin (ADM/AM)
Aldose Reductase (ALDR1)
Aldosterone Synthase B1 (CYP11B1)
Aldosterone Synthase B2 (CYP11B2)
Alpha 1A Adrenergic Receptor (ADRA1A)
Alpha 2A Adrenergic Receptor (ADRA2A)
Amylin (IAPP)
Angiotensin Converting Enzyme (ACE)
Angiotensin II Receptor 1 (AT2R1)
Angiotensin II Receptor 2 (AT2R2)
Angiotensinase C/Prolyl-CPY (PRCP)
Angiotensinogen (AGT)
Apolipoprotein A1 (APOA1)
Apolipoprotein A2 (APOA2)
Apolipoprotein C2 (APOC2)
Apolipoprotein C3 (APOC3)
Apolipoprotein C4 (APOC4)
Apolipoprotein E (APOE)
Apolipoprotein E Receptor 2 (APOER2)
Aquaporin 2 (AQP2)
Arginine Vasopressin (AVP)
Arginine Vasopressin Receptor 1A (AVPR1A)
Arginine Vasopressin Receptor 1B (AVPR1B)
Arginine Vasopressin Receptor 2 (AVPR2)
ATP-Sensitive K Channel (KCNJ6)
Atrial Natriuretic Peptide (ANP)
B-cell K/ATP Channel (BIR/KCNJ11)
Beta 2 Adrenergic Receptor (ADRB2)
Beta 3 Adrenergic Receptor (ADRB3)
Bombesin-like Receptor 3 (BRS3)
Bradykinin Receptor B2 (BDKRB2/BKRB2)
Brain Natriuretic Peptide (BNP/NPPB)
Calcitonin/Calcitonin Gene Related Peptide (CGRP/CALCA)
Cardiac L type Calcium Channel, alpha-1 (CACNA1C/CACNL1A1)
Cdc42-Interacting Protein 4 (CIP4)
Chloride Bicarb. Exchanger 1 (AE1//SLC4A1)
Chloride Bicarb. Exchanger 2 (AE2/SLC4A2)
Chloride Bicarb. Exchanger 3 (AE3)
Chloride Channel, kidney, A (CLCNKA)
Chloride Channel, kidney, B (CLCNKB)
Chymase, heart (CYH)
Cyclooxygenase 1 (COX1/PTGS1)
Cyclooxygenase 2 (COX2/PTGS2)
Cytrochrome P450-4A (CYP4A11)
Dopamine Beta-Hydroxylase (DBH)
Dopamine Receptor D1 (DRD1)
Endothelin 1 (EDN1/ET1)
Endothelin 2 (EDN2/ET2)
Endothelin 3 (EDN3/ET3)
Endothelin Convert. Enzyme1 (ECE1)
Endothelin Receptor Type A (EDNRA)
Endothelin Receptor Type B (EDNRB)
E-Selectin (ELAM/SELE)
Galanin (GALN)
Galanin Receptor (GALNR)
Gastric Inhibitory Polypeptide Receptor (GIPR)
Gi, alpha subunit (GNAI1)
Glucagon (GCG)
Glucagon Receptor (GCGR)
Glucagon-like Peptide 1 Receptor (GLP1R)
Glucocorticoid Receptor (GRL)
Glucokinase-liver (GCK)
Glucose Transporter 1 (GLUT1)
Glucose Transporter 2 (GLUT2/SLC2A2)
Glucose Transporter 3 (GLUT3/SLC2A3)
Glucose Transporter 4 (GLUT4/SLC2A4)
Glutamine:F6P Amidotransferase (GFAT/GFPT)
Glycogen Synthase-liver (GYS2)
Glycogen Synthase-muscle (GYS1)
G-protein, beta polypeptide 3 (GNB3)
Growth Hormone 1 (GH1)
Growth Hormone 2 (GH2)
Haptoglobin (HAPT/HP)
Insulin (INS)
Insulin Promoter Factor/ Somatostatin TF (IPF1/IDX1/STF1)
Insulin Receptor (INSR)
Insulinlike Growth Factor 1 (IGF1)
Insulinlike Growth Factor 2 (IGF2)
Intercellular Adhesion Molecule 1 (ICAM-1)
Intercellular Adhesion Molecule 2 (ICAM-2)
Intercellular Adhesion Molecule 3 (ICAM-3)
Kallikrein, glandular (KLK1)
Kallistatin (KST/PI4)
Kininogen (KNG)
LDL Receptor (LDLR)
Leptin (LEP/OB)
Leptin Receptor (LEPR)
Lipoprotein Lipase (LPL)
Methylenetetrahydrofolate Reductase (MTHFR)
Mineralocorticoid Receptor (MLR)
Natriuretic Peptide Receptor A/Guanyl Cyclase A (NPR1/ANPRA)
Natriuretic Peptide Receptor B (NPR2/ANPRB)
Natriuretic Peptide Receptor C (NPR3/ANPRC)
Natriuretic Peptide type C (NPPC)
Neuropeptide Y (NPY)
Neuropeptide Y Receptor 1 (NPY1R)
Nitric Oxide Synthase, endothelial (NOS3)
Nitric Oxide Synthase, inducible (NOS2/NOS2A)
Nitric Oxide Synthase, neuronal (NOS1)
Norepinephrine Transporter Protein 1 (NET1)
Parathyroid Hormone Receptor (PTHR1)
Parathyroid Hormone-Related Protein (PTHRP/PTHLH)
Phenylethanolamine N-Methyltransferase (PNMT)
Phospholipase A2 (PLA2/PLA2A)
Potassium-chloride cotransporter (hKCC1)
Prostacyclin Synthase (PGIS/PTGIS)
Prostacyclin Receptor (PTGIR)
Prostaglandin E Receptor 2 (PTGER2)
Prostaglandin E Receptor 3 (PTGER3)
Protein Kinase C isozyme-Epsilon (PRKCE)
Protein Kinase C isozyme-Theta (PRKCQ)
Protein Phosphatase 1, gamma subunit (PPP1G)
Protein Phosphatase 1, alpha subunit (PPP1A)
Renin (REN)
Renin-Binding Protein (RENBP)
Sodium Bicarbonate Cotransporter (NBC/HNBC1)
Sodium Calcium Exchanger 1 (NCX1/SLC8A1)
Sodium Calcium Exchanger 2 (NCX2/SLC8A2)
Sodium Channel (SCNN1A)
Sodium Channel (SCNN1B)
Sodium Channel (SCNN1D)
Sodium Channel (SCNN1G)
Sodium Channel - Heart (SCN5A)
Sodium Chloride Cotransporter (SLC12A3/HTSC)
Sodium Hydrogen Exchanger 1 (NHE1/SLC9A1)
Sodium Hydrogen Exchanger 2 (NHE2/SLC9A2)
Sodium Hydrogen Exchanger 5 (NHE5/SLC9A5)
Sodium Potassium ATPase alpha1 (ATP1A1)
Sodium-Glucose Cotransporter, renal (SGLT2/SLC5A2)
Subtractive Clone A (SA)
Sulfonylurea Receptor (SUR)
Thrombin Receptor (TR/CF2R/PAR1/F2R)
Thromboxane A Synthase (TBXAS1)
Thromboxane A2 Receptor (TBXA2R)
Thyrotropin Releasing Hormone (TRH)
Thyrotropin Releasing Hormone Receptor (TRHR)
Transforming Growth Factor Beta 1 (TGFB1)
Tyrosine Hydroxylase (TH)
Uncoupling Protein 3 (UCP3)
Vascular Endothelial Growth Factor A (VEGFA)
Vascular Endothelial Growth Factor B (VEGFB)
Vascular Endothelial Growth Factor C (VEGFC)
List By Gene Symbols | List By Gene Function | GIST | Chakravarti Lab


This site has been created and maintained by Jeff Bailey and Marc Halushka.