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We have made all hypertension candidate gene SNPs detected through the collaboration of Affymetrix Inc. and
the Chakravarti laboratory at Case Western Reserve University available here. Below is a list of 116 candidate genes for which at least a single SNP exists.
Each gene is clickable and will open to a new web page showing all available SNPs.
SNP data includes location, heterozygosity class, confirmation status and type of change.
If you would like a tab-delimited text file of this information, click here.
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| More Gene Information | GIST |
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| # of SNPs | Gene Name |
| 1 | Adenosine Deaminase (ADA) |
| 14 | Alpha Adducin (ADD1) |
| 8 | Beta Adducin (ADD2) |
| 1 | Gamma Adducin (ADD3) |
| 12 | Adrenomedullin (ADM) |
| 4 | Adenosine A2 Receptor (ADORA2A) |
| 6 | Beta 2 Adrenergic Receptor (ADRB2) |
| 7 | Beta 3 Adrenergic Receptor (ADRB3) |
| 17 | Angiotensinogen (AGT) |
| 8 | Angiotensin II Receptor 1 (AGTR1) |
| 5 | Angiotensin II Receptor 2 (AGTR2) |
| 10 | Aldehyde Reductase (ALDR1) |
| 13 | Apolipoprotein A1 (APOA1) |
| 7 | Apolipoprotein A2 (APOA2) |
| 22 | Apolipoprotein A4 (APOA4) |
| 3 | Apolipoprotein B (APOB) |
| 10 | Apolipoprotein C1 (APOC1) |
| 8 | Apolipoprotein C2 (APOC2) |
| 19 | Apolipoprotein C3 (APOC3) |
| 26 | Apolipoprotein C4 (APOC4) |
| 1 | Plasma Membrane Calcium ATPase, Type 1 (ATP2B1) |
| 1 | Arginine Vasopressin (AVP) |
| 9 | Arginine Vasopressin Receptor 2 (AVPR2) |
| 4 | Bradykinin Receptor Beta 2 (BDKRB2) |
| 6 | Bombesin-like Receptor 3 (BRS3) |
| 8 | Calcitonin/Calcitonin Gene Related Peptide (CALCA) |
| 3 | Calcium Sensing Receptor (CASR) |
| 3 | Cadherin 1 (CDH1) |
| 7 | Chloride Channel 6 (CLCN6) |
| 10 | Chloride Channel, Kidney, B (CLCNKB) |
| 7 | Chymase, Heart (CYH) |
| 29 | 11 Beta Hydroxylase (CYP11B1) |
| 25 | Aldosterone Synthase (CYP11B2) |
| 6 | Cytochrome P450, Subfamily IIA (CYP2A) |
| 1 | Cytochrome P450, Subfamily IIIA, Polypeptide 4 (CYP3A4) |
| 9 | Dopamine Beta Hydroxylase (DBH) |
| 21 | Angiotensin Converting Enzyme (DCP1) |
| 8 | Dopamine Receptor D1 (DRD1) |
| 2 | Endothelin 1 (EDN1) |
| 3 | Endothelin 2 (EDN2) |
| 12 | Endothelin Receptor, Type A (EDNRA) |
| 8 | Endothelin Receptor, Type B (EDNRB) |
| 1 | Fibroblast Growth Factor Receptor 2 (FGFR2) |
| 12 | Galanin Receptor (GALR1) |
| 10 | Glucagon (GCG) |
| 5 | Glucagon Receptor (GCGR) |
| 2 | Glucokinase (GCK) |
| 1 | Glutamine Fructose 6 Phosphate Amidotransferase (GFPT1) |
| 4 | Growth Hormone 1 (GH1) |
| 1 | Growth Hormone 2 (GH2) |
| 3 | Gastric Inhibitory Polypeptide Receptor (GIPR) |
| 8 | Guanine Nucleotide Binding Protein, Beta 3 (GNB3) |
| 1 | Glucocorticoid Receptor (GRL) |
| 19 | Glycogen Synthase 1 (GYS1) |
| 13 | Haptoglobin (HP) |
| 3 | 11 Beta Hydroxysteroid Dehydrogenase, Kidney (HSD11B2) |
| 8 | Islet Amyloid Polypeptide (IAPP) |
| 14 | Intercellular Adhesion Molecule 1 (ICAM1) |
| 3 | Intercellular Adhesion Molecule 2 (ICAM2) |
| 1 | Insulin-like Growth Factor 2 (IGF2) |
| 1 | Insulin-like Growth Factor Binding Protein 1 (IGFBP1) |
| 4 | Insulin (INS) |
| 2 | Insulin Receptor (INSR) |
| 1 | Insulin Promoter Factor 1 (IPF1) |
| 2 | Insulin Receptor Substrate 2 (IRS2) |
| 19 | Potassium Channel, Inwardly Rectifying (KCNJ11) |
| 6 | Kallikrein (KLK1) |
| 1 | Leptin (LEP) |
| 2 | Leptin Receptor (LEPR) |
| 1 | Lipoprotein A (LPA) |
| 11 | Lipoprotein Lipase (LPL) |
| 13 | Apolipoprotein E Receptor 2 (LRP8) |
| 19 | Mineralocorticoid Receptor (MLR) |
| 8 | Arylamine N-Acetyltransferase 2 (NAT2) |
| 1 | Nitric Oxide Synthase 3 (NOS3) |
| 11 | Atrial Natriuretic Peptide (NPPA) |
| 4 | Brain Natriuretic Peptide (NPPB) |
| 9 | Natriuretic Peptide Precursor C (NPPC) |
| 7 | Natriuretic Peptide Receptor C (NPR3) |
| 6 | Neuropeptide Y (NPY) |
| 2 | Neuropeptide Y Receptor Y1 (NPY1R) |
| 6 | Kallistatin (PI4) |
| 7 | Phospholipase A2 (PLA2G1B) |
| 7 | Phenylethanolamine N-Methyltransferase (PNMT) |
| 2 | Paraoxonase 1 (PON1) |
| 1 | Paraoxonase 2 (PON2) |
| 37 | Prostaglandin E Receptor 3, EP3 Subtype (PTGER3) |
| 54 | Prostaglandin I2 Synthase (PTGIS) |
| 11 | Cyclooxygenase 1 (PTGS1) |
| 10 | Cyclooxygenase 2 (PTGS2) |
| 1 | Parathyroid Hormone (PTH) |
| 17 | Renin (REN) |
| 1 | Renin Binding Protein (RENBP) |
| 9 | Subtractive Clone A (SAH) |
| 5 | Sodium Channel, Nonvoltage-gated 1, Beta (SCNN1B) |
| 27 | Sodium Channel, Nonvoltage-gated 1, Gamma (SCNN1G) |
| 22 | Selectin E (SELE) |
| 3 | Selectin L (SELL) |
| 8 | Selectin P (SELP) |
| 9 | Sodium Chloride Cotransporter, Thiazide Sensitive (SLC12A3) |
| 4 | Glucose Transporter 1 (SLC2A1) |
| 16 | Glucose Transporter 2 (SLC2A2) |
| 29 | Glucose Transporter 4 (SLC2A4) |
| 1 | Glucose Transporter 5 (SLC2A5) |
| 29 | Chloride Bicarbonate Exchanger 1 (SLC4A1) |
| 2 | Sodium Glucose Transporter 1 (SLC5A1) |
| 13 | Norepinephrine Transporter (SLC6A2) |
| 26 | Sodium Calcium Exchanger 1 (SLC8A1) |
| 1 | Sodium/Hydrogen Exchanger 1 (SLC9A1) |
| 20 | Thromboxane A2 Receptor (TBXA2R) |
| 16 | Thromboxane A Synthase 1 (TBXAS1) |
| 4 | Transforming Growth Factor, Beta 1 (TGFB1) |
| 1 | Transforming Growth Factor, Beta 2 (TGFB2) |
| 1 | Transforming Growth Factor, Beta Receptor, Type III (TGFBR3) |
| 13 | Thyrotropin Releasing Hormone (TRH) |
| 14 | Thyrotropin Releasing Hormone Receptor (TRHR) |
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| Candidate Gene Information | GIST | Chakravarti Lab | |