Hypertension: Mechanisms

• Preface
• Chapter1 -- Pathogenesis of Hypertension: Genetic and Environmental Factors
• -- Genetic Factors in Hypertension
• -- Environmental Factors in Hypertension
• -- Gene- Environmental Interactions
• Chapter 2 -- Role of the Nervous System in Human Hypertension
• -- Functional Organization of the Autonomic Nervous System
• -- Factors Affecting the Autonomic Control of Blood Pressure
• -- Testing Autonomic Function in Humans
• -- Involvement of the Autonomic Nervous System in Human Hypertension
• Chapter 3 -- Hypertension: Kidney, Sodium, and the Renin - Angiotensin System 
• -- Anatomy and Physiology
• -- Pathophysiology
• -- Renovascular Hypertension
• Chapter 4 -- Pathogenesis of Hypertension: Vascular Mechanisms
• -- Identification of Problem
• -- Morphologic Changes in Hypertension
• -- Mechanisms Underlying Structural Changes
• -- Functional Alterations in Hypertension
• Chapter 5 -- Natural History of Cardiovascular Risk
• -- Overview
• -- Lifestyles
• -- Atherogenic Traits
• -- Indicators of Compromised Arterial Circulation
• -- Innate Susceptibility. Risk Factors in the Elderly, and Sudden Death
• -- Multivariate Risk
• Chapter 6 -- Secondary Hypertension: Adrenal and Nervous Systems
• -- Adrenocortical Causes of Hypertension
• -- Hypertensive Syndromes Secondary to Hypersecretion of Deoxycorticosterone
• -- Hypertensive Syndromes Secondary to Cortisol Excess
• -- Hypertensive Syndromes Secondary to Hypersecretion of Aldosterone
• -- Pheochromocytom

            Hypertension: Therapy

• Chapter 7 -- Antihypertensive Agents: Mechanisms of Drug Action 
• -- Individualized Antihypertensive Therapy 
• -- Diuretics
• -- β-Blockers
• -- Angiotensin-Converting Enzyme Inhibitors
• -- Calcium Antagonists
• -- Other Agents
• -- Metabolic Effects of Antihypertensive Drugs
• -- Regression of Vascular and Cardiac Hypertrophy
• Chapter 8 -- The Therapeutic Trials
• -- Trends in Cardiovascular Disease
• -- Clinical Trials Prior to 1990
• -- Meta-Analysis of Pre-1990Trials
• Chapter 9 -- Antihypertensive Therapy: Patient Selection and Special Problems
• -- Hypertension and Cardiovascular Risk 
• -- Nonpharmacologic Therapy
• -- Factors in the Selection of Antihypertensives
• -- Concomitant disease and Quality of Life
• Chapter 10 -- Antihypertensive Therapy: Progression of Renal Injury
• -- Overview
• -- Epidemioloht
• -- Neurohormonal Responses
• -- Theoretical Concerns About Renal Perfusion
• -- Antihypertensive Therapies
• -- Experimental Trials with ACE Inhibitors
• -- Human Clinical Trials
• -- Future Considerations
• Chapter 11 -- Antihypertensive Therapy: Compliance and Quality of Life
• -- Background
• -- Assessment Techniques
• -- Application to Antihypertensive Therapy
• -- Clinical Relevance and Sensitivity
• -- Future Directions
• Chapter 12 -- Special Situations in the Management of Hypertension
• -- Hypertension in Pregnancy
• -- Hypertension at the Extremes of Age
• -- Hypertension at the Extremes of Severity
• -- Hypertension-Causing Drugs
• -- Specialized Methods of Blood Pressure Measurement