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Ultrasound filters fat from blood

Surgery aid could reduce post-operative brain damage.
2 October 2002

CHARLOTTE WESTNEY

Blood comes out of the filter 95% fat free.
© H.Jonsson

A new filter fires ultrasound at tiny tubes of blood to separate out blobs of fat. The device could stop fat getting into the brain during heart surgery, say its Swedish developers.

On the operating table, leaking blood is sucked up and put back into a patient. Fat from the heart, arteries and bone marrow seeps into this blood. This fat can accumulate in the brain, where it is thought to cause the memory and movement impairments seen in up to two-thirds of patients after heart surgery - around 3 per cent suffer strokes.

The new filter squeezes blood through hair-thin channels. Different components in the blood react to ultrasound waves in different ways - fat is pushed to the sides of the channels. The blood that comes out is 95 per cent fat-free.

"We have very big hopes," for its medical use, says Henrik Jonsson, who helped devise the filter at the Lund Institute of Technology in Sweden. Clinical trials are planned for next year.

Some surgeons use screen filters, but fat can pass through the pores only to reform as larger blobs on the other side.

The new filter "shows great promise in treating blood" agrees Dixon Moody, who studies the post-operative impact of fat on the brain at Wake Forest University in North Carolina. But to be useful in the operating theatre, he warns, it will have to process at least a litre of blood an hour - the filter currently manages only 300 millilitres.

The team hopes to increase its capacity by running 200 channels in parallel. The final device should look like a compact-disc case. "It's a neat contraption," comments Moody.

And it should have other uses. Already the filter has separated cream from milk; it could help in water purification and even dialysis. It will be displayed at the Technology Fair in Ålvsjö, Sweden, next week.


© Nature News Service / Macmillan Magazines Ltd 2002

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