• Transcriptional control thrown for a loop
• Transcriptional control of pluripotency
• Signaling meets chromatin during tissue regeneration in Drosophila
• Remodeling plans for cellular specialization
• Polycomb response elements and targeting of Polycomb group proteins in Drosophila
• Myogenic progenitor cells and skeletal myogenesis in vertebrates
• Molecular control of pluripotency
• MicroRNAs in muscle differentiation
• Histone demethylation and androgen-dependent transcription
• Hematopoietic stem cell self-renewal
• Guiding embryonic stem cells towards differentiation
• Genomic programs and differentiation
• Epigenetic alchemy for cell fate conversion
• Epidermal stem cells
• Breaking out of the mold-diversity within adult stem cells and their niches
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• Viral serotype and the transgene sequence influence overlapping adeno-associated viral (AAV) vector-mediated gene transfer in skeletal muscle
• Serotype-specific replicating AAV helper constructs increase recombinant AAV type 2 vector production
• respir-Adeno-Associated Virus-Mediated Gene Transfer for Lung Diseases
• Recombinant adeno-associated viral vectors as therapeutic agents to treat neurological disorders
• Production of Recombinant Adeno-Associated Virus Vectors
• Prevalence of Neutralizing Antibodies Against Adeno-Associated Virus (AAV) Types 2, 5, and 6 in Cystic Fibrosis
• Mutagenesis and Oncogenesis by Chromosomal Insertion of Gene Transfer Vectors
• Long-Term Inducible Gene Expression in the Eye via Adeno-Associated Virus Gene Transfer
• Long-Term Efficacy of Adeno-Associated Virus Serotypes 8 and 9 in Hemophilia A Dogs and Mice
• Gene Targeting by Adeno-Associated Virus Vectors Is Cell-Cycle Dependent
• Efficient AAV1–AAV2 Hybrid Vector for Gene Therapy of Hemophilia
• Directed evolution of adeno-associated virus yields enhanced gene delivery vectors
• Determination of Specific CD4 and CD8 T Cell Epitopes after AAV2-and AAV8-hF.IX Gene Therapy
• Custom Adeno-Associated Virus Capsids
• Convection-Enhanced Delivery of Adeno-Associated Virus Type 2 (AAV2) into the Striatum
• Combinatorial engineering of a gene therapy vector
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• Nerve Growth Factor Improves the Muscle Regeneration Capacity of Muscle Stem Cells in Dystrophic Muscle
• Hematopoietic Stem Cell Transduction by Recombinant Adeno-Associated Virus Vectors-Problems and Solutions
• Hematopoietic Stem Cell Transduction and Amplification in Large Animal Models
• Gene-Induced Chondrogenesis of Primary Mesenchymal Stem Cells in vitro
• Efficient non-viral transfection of adult neural stem-progenitor cells, without affecting viability, proliferation or differentiation
• diabetes-Human Bone Marrow Mesenchymal Stem Cells Transfected with Human Insulin Genes Can Secrete Insulin Stably
• Correction of murine hemophilia a by hematopoietic stem cell gene therapy
• Competitive Engraftment of Hematopoietic Stem Cells Genetically Modified with a Truncated Erythropoietin Receptor
• Hematopoietic Stem and Progenitor Cell Transduction In Vitro and In Vivo by Recombinant Adeno-Associated Virus Vector Serotypes 1 Through 5
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• Transposable elements, gene creation and genome rearrangement in flowering plants
• The microbial pan-genome
• Short, local duplications in eukaryotic genomes
• Hemiascomycetous yeasts at the forefront of comparative genomics
• genomic consequences of intracellular mutualism and parasitism
• Conserved sequences and the evolution of gene regulatory signals
• Comparative genomics of malaria parasites
• Comparative genomics as a tool in the understanding of eukaryotic transcriptional regulation
• Common themes in the genome strategies of pathogens
• Chromosomal sex-determining regions in animals, plants and fungi
• Causes and effects of nuclear genome reduction
• Ancestral state reconstructions for genomes
• The power of comparative genomics
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• Will tomorrow's medicines work for everyone
• unexamined population
• Implications of correlations between skin color and genetic ancestry for biomedical research
• Implications of biogeography of human populations for 'race' and medicine
• Genetic variation, classification and 'race'
• Forensic genetics and ethical, legal and social implications beyond the clinic
• Conceptualizing human variation
• Changing the paradigm from 'race' to human genome variation
• Assessing genetic contributions to phenotypic differences among 'racial'
• Are medical and nonmedical uses of large-scale genomic markers conflating genetics and 'race'
• Race and the human genome
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• Transcription and processing of human microRNA precursors
• Structural aspects of microRNA
• Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme
• Predicting and validating microRNA targets
• Nuclear export of microRNA precursors
• MicroRNA precursors in motion
• MicroRNA biogenesis
• MicroRNA biogenesis
• Dependent Trans-Acting siRNA Production
• Common logic of transcription factor and microRNA action
• A Journal-Club Discussion of Regulation by microRNA
• RNA, A Multifunctional Molecule
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• Finding schizophrenia genes
• The genetic epidemiology of neurodegenerative disease
• Mapping the new frontier_complex genetic disorders
• Mapping quantitative trait loci in humans
• Linkage disequilibrium maps and association mapping
• Factors affecting statistical power in the detection of genetic association
• Genetic epidemiology of diabetes
• THE GENETICS OF ADDICTIONS
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• Transcriptional regulation by the numbers-2
• Transcriptional regulation by the numbers
• The structure and function of the bacterial chromosome
• Revisited gene regulation in bacteriophage λ
• Recognition and modification of seX chromosomes
• MicroRNAs
• The key to development-interpreting the histone code
• DNA looping in gene regulation
• Controlling DNA methylation
• Chromosomes and gene expression mechanisms
• Chromatin remodeling complexes
• Centromeric chromatin
• bi-sb-Computational methods for transcriptional regulation
• Current Opinion in Genetics & Development
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• Structure and evolution of transcriptional regulatory networks
• structural perspective on protein–protein interactions
• Protein interaction networks from yeast to human
• Metabolic networks-enzyme function and metabolite structure
• interplay of fold recognition and experimental structure determination in structural genomics
• genetics-Recent advances in gene structure prediction
• evolving roles of alternative splicing
• Computational exploration of structural information from cryo-electron tomograms
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• Use of siRNAs to prevent and treat influenza virus infection
• Silencing structural and nonstructural genes in baculovirus by RNA interference
• RNA silencing of rotavirus gene expression
• RNA silencing in viral infections
• RNA silencing-a conserved antiviral immunity of plants and animals
• RNA interference, arthropod-borne viruses, and mosquitoes
• RNA interference as a new biotechnological tool for the control of virus diseases in plants
• RNA interference against retroviruses
• Plant viral suppressors of RNA silencing
• Interfering with hepatitis C virus RNA replication
• Generation of an shRNAi expression library against the whole human transcripts
• Derivation and function of small interfering RNAs and microRNAs
• Control of nonsegmented negative-strand RNA virus replication by siRNA
• RNAi and Viral Gene Silencing by RNA Interference
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• Structure-Based Functional Inference In Structural Genomics
• Structural Genomics Efforts At The Chinese Academy Of Sciences And Peking University
• Secure Web Book To Store Structural Genomics Research Data
• Protein Crystallization For Genomics
• Project Management System For Structural And Functional Proteomics
• Practical Application Of Transcriptional Sequencing For Gc-Rich Templates
• Patent Protection For Structural Genomics-Related Inventions
• Multi-Domain Protein Families And Domain Pairs
• More For Less In Structural Genomics
• Major Transitions In Evolution By Genome Fusions
• Gene Duplication And Other Evolutionary Strategies-From The Rna World To The Future
• From Protein Structure To Biochemical Function
• Detection Of Gene Duplications And Block Duplications In Eukaryotic Genomes
• Characteristics And Prediction Of Domain Linker Sequences In Multi-Domain Proteins
• Cdna Network Cdnas, Functional Genomics And Proteomics
• Coverage Of Protein Sequence Space By Current Structural Genomics Targets
• Screening Methods To Determine Biophysical Properties Of Proteins In Structural Genomics
• protein folding-Structural genomics-An approach to the protein folding problem
• protein folding-Protein structure prediction and structural genomics
• Protein expression systems for structural genomics and proteomics
• Overview of structural genomics-from structure to function
• Structural Biology-and Structural Genomics-Proteomics
• Plug and Play-expression systems for high-quality production of recombinant proteins for structural analysis
• Establishing a structural genomics platform
• Structural genomics on metalloproteins
• Structural genomics of non-standard proteins
• structural genomics in Europe
• Nuclear Magnetic Resonance in the Era of Structural Genomics
• Structural genomics of proteins from conserved biochemical pathways and processes
• Molecular genetics and structural genomics of the human protein kinase C gene module
• The Promise of Structural Genomics in the Discovery of New Antimicrobial Agents
• IEngineering soluble proteins for structural genomics
• Engineering soluble proteins for structural genomics
• Structural genomics analysis
• Targeting novel folds for structural genomics
• Structural genomics-shaping the future of drug design
• Structural genomics and signaling domains
• Protein Structure Prediction and Structural Genomics
• Global Efforts in Structural Genomics
• Structural genomics-shaping the future of drug design
• SCOP database in 2002-refinements accommodate structural genomics
• Functional and structural genomics using PEDANT
• Next generation therapeutics-Structural genomics- opportunities and challenges
• Structural genomics takes off
• A rapid classification protocol for the CATH Domain Database to support structural genomics
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• Tools For Targeted Manipulation Of The Mouse Genome
• Skeletal development, insights from targeting the mouse genome
• The Mouse Secretome-Functional Classification Of The Proteins Secreted Into The Extracellular Environment
• Targeting-Complex Transcriptome-The Construction Of The Mouse Full-Length Cdna Encyclopedia
• Systematic Expression Profiling Of The Mouse Transcriptome Using Riken Cdna Microarrays
• Systematic Characterization Of The Zinc-Finger-Containing Proteins In The Mouse Transcriptome
• Phosphoregulators-Protein Kinases And Protein Phosphatases Of Mouse
• Mouse Proteome Analysis
• Kinesin Superfamily Proteins (Kifs) In The Mouse Transcriptome
• Impact Of Alternative Initiation, Splicing, And Termination On The Diversity Of The Mrna Transcripts Encoded By The Mouse Transcriptome
• Identification Of-Large Novel Imprinted Gene Cluster On Mouse Proximal Chromosome 6
• Identification Of Putative Noncoding Rnas Among The Riken Mouse Full-Length Cdna Collection
• Identification And Analysis Of Chromodomain-Containing Proteins Encoded In The Mouse Transcriptome
• Human-Mouse Alignments With Blastz
• Human Disease Genes And Their Cloned Mouse Orthologs
• Genelynx Mouse-Integrated Portal To The Mouse Genome
• G Protein-Coupled Receptor Genes In The Fantom2 Database
• Exploration Of The Cell-Cycle Genes Found Within The Riken Fantom2 Data Set
• Dna Book
• Discovery Of Imprinted Transcripts In The Mouse Transcriptome Using Large-Scale Expression Profiling
• Differential Expansion Of Zinc-Finger Transcription Factor Loci In Homologous Human And Mouse Gene Clusters
• Dentification Of Putative Noncoding Rnas Among The Riken Mouse Full-Length Cdna Collection
• Continued Discovery Of Transcriptional Units Expressed In Cells Of The Mouse Mononuclear Phagocyte Lineage
• Connecting Sequence And Biology In The Laboratory Mouse
• Comprehensive Analysis Of The Mouse Metabolome Based On The Transcriptome
• Comparative Proteomics Of Ubiquitination In Mouse
• -Comparative Gene Prediction In Human And Mouse
• Comparative Analysis Of Apoptosis And Inflammation Genes Of Mice And Humans
• Cds Annotation In Full-Length Cdna Sequence
• Analysis Of The Mouse Transcriptome For Genes Involved In The Function Of The Nervous System
• A Comprehensive Transcript Map Of The Mouse Gnas Imprinted Complex
• High-throughput engineering of the mouse genome coupled with high-resolution expression analysis
• Manipulation of the mouse genome-a multiple impact resource for drug discovery and development
• Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles
• Tools for targeted manipulation of the mouse genome
• The real deal
• A forage in the junkyard
• The mouse genome
• The mouse genome timeline
• The mouse-genetics meets behaviour
• The mosaic structure of variation in the laboratory mouse genome
• Single nucleotide polymorphisms-Tackling complexity
• Sequence Tells Mouse, Human Genome Secrets
• Recombineering-a powerful new tool for mouse functional genomics
• Piecing it all together
• Numerous potentially functional but non-genic conserved sequences on human chromosome 21
• Mouse genome-The real deal
• Mouse genome-A forage in the junkyard
• Mouse genetics-Full house
• Mining the mouse genome
• Initial sequencing and comparative analysis of the mouse genome
• Human chromosome 21 gene expression atlas in the mouse
• Gene-trap mutagenesis-past, present and beyond
• Functional genomics-A time and place for every gene
• Functional annotation of a full-length mouse cDNA collection
• Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei
• Engineering chromosomal rearrangements in the mouse
• Conditional control of gene expression in the mouse
• Comparative genomics-The mouse that roared
• Capitalizing on large-scale mouse mutagenesis screens
• Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs
• A physical map of the mouse genome
• A gene expression map of human chromosome 21 orthologues in the mouse
• Mouse genome web focus
• hail the humble mouse
• Functional Annotation of Mouse Genome Sequences
• A PERSONAL HISTORY OF THE MOUSE GENOME
• Progress in sequencing the mouse genome
• The six hyaluronidase-like genes in the human and mouse genomes
• The Mouse Genome Database (MGD)-the model organism database for the laboratory mouse
• Functional Annotation of Mouse Genome Sequences
• The Mouse Genome Database (MGD)- integration nexus for the laboratory mouse
• The Jackson Laboratory Mouse Genome Informatics
• The 1999 Chromosome Committee Reports for the Mouse Genome Introduction
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• X-Linked Extension Of The Revised Haseman-Elston Algorithm For Linkage Analysis In Sib Pairs
• Regression-Based Sib Pair Linkage Analysis For Binary Traits
• Regression Models For Linkage
• Pleiotropy And Heterogeneity In The Expression Of Atherogenic Lipoproteins
• Number Of Snps Loci Needed To Detect Population Structure
• Mapping Quantitative Trait Loci Using Multiple Phenotypes In General Pedigrees
• Linkage Analysis Of Quantitative Trait Loci In The Presence Of Heterogeneity
• Information Perspectives Of The Haseman-Elston Method
• Efficiency Robust Tests For Mapping Quantitative Trait Loci Using Extremely Discordant Sib Pairs
• Effect Of Box-Cox Transformation On Power Of Haseman-Elston And Maximum-Likelihood Variance Components Tests
• Adding Further Power To The Haseman And Elston Method For Detecting Linkage In Larger Sibships
• A Simple Nonparametric Test For Linkage With Sib-Pair Censored Event Time Observations
• A Method For Evaluating The Results Of Bayesian Model Selection
• A Comprehensive Method For Genome Scans
• Recent Advances In The Analysis Of Genetic Traits
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• The Snp Consortium-Summary Of-Private Consortium Effort To Develop An Applied Map Of The Human Genome
• The Challenge Of Using Snps In The Understanding And Treatment Of Disease
• Templiphi-29 Dna Polymerase Based Rolling Circle Amplification Of Templates For Dna Sequencing
• Strategy For The Rapid Discovery Of Disease Markers Using The Massarray System
• Snpstream Uht-Ultra-High Throughput Snp Genotyping For Pharmacogenomics And Drug Discovery
• Snp Market View-Opportunities, Technologies, And Products
• Primer Design For Pcr And Sequencing In High-Throughput Analysis Of Snps
• New Generation Pharmacogenomic Tools--Snp Linkage Disequilibrium Map
• Characterization Of Cytochrome P45 2d6 Alleles Using The Invader' System
• Beadarray-Technology-Enabling An Accurate, Cost-Effective Approach To High-Throughput Genotyping
• Discovery Of Markers For Disease
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• The Atr-Independent Dna Replication Checkpoint
• Self-Regulating Model For Control Of Replication Origin Firing In Budding Yeast
• Replication Origins
• Replication Of Damaged Dna
• Multiple Roles Of Replication Forks In-Phase Checkpoints-Sensors, Effectors And Targets
• Multiple Roles For Kinases In Dna Replication
• Mechanisms Controlling The Integrity Of Replicating Chromosomes In Budding Yeast
• Maintaining Transcriptional States Through Dna Replication
• Linking-Phase To Chromatin Structure And Chromosome Dynamics
• Essence Of Replication Timing-Determinants And Significance
• Dna Replication In The Face Of (In)Surmountable Odds
• Cyclin-Dependent Kinases And-Phase Control In Mammalian Cells
• Connecting Orc And Heterochromatin-Why
• DNA replication of mitotic chromatin in Xenopus egg extracts
• A Complex Matter
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• Ancient horizontal gene transfer
• EVOLUTION EXPERIMENTS WITH MICROORGANISMS
• GENETIC STRATEGIES FOR ANTIBACTERIAL DRUG DISCOVERY
• Genome evolution in bacterial endosymbionts of insects
• Genomics- Relative pathogenic values
• Mice, microbes and models of infection
• Neurospora- a model of model microbes
• No post-genetics era in human disease research
• Progress and problems with the use of viral vectors for gene therapy
• Redefining bacterial populations-a post-genomic reformation
• THE ART AND DESIGN OF GENETIC SCREENS- ESCHERICHIA COLI
• The evolutionary genomics of pathogen recombination
• THE FUTURE OF BACTERIOPHAGE BIOLOGY
• VAlternate replication in B cells and epithelial cells switches Epstein-Barr virus tropism
• VAn antisense-based functional genomics approach for genes critical for growth of Candida albicans
• VGenome sequence of the human malaria parasite Plasmodium falciparum
• VGenome-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori
• Virus evolution- The importance of being erroneous
• VIsolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
• VRedefining bacterial populations- a post-genomic reformation
• VViral mimicry of cytokines, chemokines and their receptors
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• A transgenic insertion upstream of Sox9 is associated with dominant XX sex reversal in the mouse
• Abundant gene conversion between arms of palindromes in human and ape Y chromosomes
• DMY is a Y-specific DM-domain gene required for male development in the medaka fish
• Human mtDNA and Y-chromosome variation is correlated with matrilocal versus patrilocal residence
• Human spermatozoa- The future of sex
• Male development of chromosomally female mice transgenic for Sry
• physical map of the human Y chromosome
• Reduced adaptation of a non-recombining neo-Y chromosome
• Retroposition of autosomal mRNA yielded testis-specific gene family on human Y chromosome
• Strong male-driven evolution of DNA sequences in humans and apes
• Tales of the Y chromosome
• The application of molecular genetic approaches to the study of human evolution
• THE HUMAN Y CHROMOSOME, IN THE LIGHT OF EVOLUTION
• The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes
• Unexpectedly similar rates of nucleotide substitution found in male and female hominids
• Y chromosome sequence variation and the history of human populations
• Y-chromosome variation and Irish origins
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• Disease related genes-Cholestasis
• Chronic pancreatitis and cystic fibrosis
• Genetic testing for polyposis- practical and ethical aspects
• Haemochromatosis
• How to identify the genetic basis of gastrointestinal and liver diseases
• Irruption of genomics in the search for disease related genes
• Multidrug resistance 1 gene (P-glycoprotein 170)- an important determinant in gastrointestinal disease
• Pharmacogenomics- marshalling the human genome to individualise drug therapy
• The promise of gene therapy in gastrointestinal and liver diseases

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• Genetics-Genetic testing and the family
• Breast cancer survivors' attitudes about communication of breast cancer risk to their children
• Communication about carrier testing within hemophilia A families
• Communication of BRCA1 and BRCA2 results to at-risk relatives
• Disclosure, confidentiality, and families
• Duty to warn at-risk relatives for genetic disease
• Effect of family history on disclosure patterns of cystic fibrosis carrier status
• Effects of spouses on distress experienced by BRCA1 mutation carriers over time
• How families communicate about HNPCC genetic testing
• Perceptions of reproductive risk and carrier testing among adolescent sisters of males with chronic granulomatous disease
• Social and familial context of prenatal genetic testing decisions

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• AAV vectors- pros, cons and recent insights
• Adeno-associated virus vectors for gene therapy
• Toward a New Generation of Conditionally Replicating Adenoviruses
• Highly Efficient Lentiviral Vector-Mediated Transduction of Nondividing, Primary Hepatocytes
• Adenoviral E1A-everlasting tool, versatile applications, continuous contributions and new hypotheses
• Adenovirus Vector-Induced Inflammation
• Adeno-associated Virus for Cancer Gene Therapy
• Hexon Gene Switch Strategy for the Generation of Chimeric Recombinant Adenovirus
• Recombinant Semliki Forest virus as a vector for selective into balloon-injured aorta
• Baculovirus as Mammalian Cell Expression Vector for Gene Therapy
• Novel Integrating Adenoviral-Retroviral Hybrid Vector for Gene Therapy
• Highly Efficient Retroviral Gene Transfer Based on Centrifugation-Mediated Vector
• retroviral vector regulate silencing
• Design of HIV Vectors for Efficient Gene Delivery into Human Hematopoietic Cells
• A Novel, Helper-Dependent, Adenovirus-Retrovirus Hybrid Vector
• Improved Method of Recombinant AAV2 Delivery for Systemic Targeted Gene Therapy
• Highly Efficient Gene Transfer into Primate Embryonic Stem Cells with a Simian Lentivirus Vector
• a Real-Time Quantitative PCR-Based Method for the Titration of AAV-2 Vector Stocks
• Evolution of Adenoviruses as Gene Therapy Vectors
• AAV-type 2 mediates highly efficient gene transfer in regenerating skeletal muscle
• Replication and packaging of helper-dependent adenoviral vectors
• An Adenoviral Expression System for AAV Rep78 Using Homologous Recombination
• Apical barriers to airway epithelial cell gene transfer with amphotropic retroviral vectors
• Recombinant Adeno-Associated Virus Serotype 2 Vectors Mediate from Salivary Glands into the Bloodstream
• Gene transduction efficiency in cells of different species by HIV and EIAV vectors
• Lentiviral Gene Transduction of Kidney
• Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy
• Viruses as gene delivery vectors-Application to gene function, target validation, and assay development
• ADENOVIRUS-5 E1A- PARADOX AND PARADIGM
• Development of lentiviral vectors for gene therapy for human diseases
• Chromosomal effects of adeno-associated virus vector integration
• delivery-Recombinant baculoviruses as mammalian cell gene-delivery vectors
• Semliki Forest virus vectors-efficient vehicles for in vitro and in vivo gene delivery

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• Debate Surges Over the Origins of Genomic Defects in Cancer
• Maintenance of Genome Stability in Saccharomyces cerevisiae
• Genome Instability-Unstable Path To Cancer
• Checking That Replication Breakdown Is Not Terminal
• Connecting Chromosomes, Crisis, and Cancer
• Interfaces Between the Detection, Signaling, and Repair of DNA Damage
• Retrotransposition and Genome Instability
• The Role of Genetic Instability in Tumor Growth Challenge of a Concept
• Cancer Prevention-Molecular Mechanisms to Clinical Applications-Genetic Instability in Epithelial Tissues at Risk for Cancer
• How carcinogens (or telomere dysfunction) induce genetic instability
• genome instability
• Inherited and inducible chromosomal instability-a fragile bridge between genome integrity mechanisms and tumourigenesis
• DNA mismatch repair and genetic instabilty
• Epigenetic Instability in ES Cells and Cloned Mice
• A genome-wide study of microsatellite instability in advanced gastric carcinoma
• Microsatellite instability as a tool for the classification of gastric cancer
• Mitochondrial genome instability in human cancers
• DNA helicases, genomic instability, and human genetic disease
• Centrosome abnormalities, genomic instability and carcinogenic progression
• DNA Damage, Genome Instability, and Cancer
• Regulated Genomic Instability and Neoplasia

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• DNA mismatch repair and mutation avoidance pathways
• DNA repair in terminally differentiated cells
• DNA Repair-
• A molecular mechanism for DNA damage recognition by the xeroderma pigmentosum group C protein complex
• Activities of human DNA polymerase in response to the major benzo[a]pyrene DNA adduct
• Alkylation resistance of E. coli cells expressing different isoforms of human alkyladenine DNA glycosylase (hAAG),
• Ambiguous coding is required for the lethal interaction between methylated DNA bases and DNA mismatch repair
• ATM deficiency and oxidative stress
• Base excision repair and nucleotide excision repair contribute to the removal of N-methylpurines from active genes
• carboxy-terminal domain of the XPC protein plays a crucial role in nucleotide excision repair through interactions with transcription factor IIH
• Cellular roles of DNA polymerase and Rev1 protein
• Characterization of the slow-growth phenotype of S. cerevisiae whip-mgs1 sgs1 double deletion mutants
• Complementation between N-terminal Saccharomyces cerevisiae mre11 alleles in DNA repair and telomere length maintenance,
• Defending genome integrity during S-phase-putative roles for RecQ helicases and topoisomerase
• Defining interactions between DNA-PK and ligase IV-XRCC4
• DNA repair capacity after-irradiation and expression profiles of DNA repair genes in resting and proliferating human peripheral blood lymphocytes
• DNA repair in terminally differentiated cells
• Down-regulation of DNA repair synthesis at DNA single-strand interruptions in poly(ADP-ribose) polymerase-1 deficient murine cell extracts
• Effects of hexavalent chromium on the survival and cell cycle distribution of DNA repair-deficient S. cerevisiae
• Excision of 8-methylguanine site-specifically incorporated into oligonucleotide substrates by the AlkA protein of Escherichia coli
• HSM2 (HMO1) gene participates in mutagenesis control in yeast
• In pursuit of a molecular mechanism for adaptive gene amplification
• Inactivation of mammalian 8-oxoguanine-DNA glycosylase by cadmium(II)-implications for cadmium genotoxicity
• Involvement of DNA polymerase in protection against the cytotoxicity of oxidative DNA damage
• Mitochondrial targeting of human 8-oxoguanine DNA glycosylase hOGG1 is impaired by a somatic mutation found in kidney cancer
• Mouse mutant database relevant to cellular responses to DNA damage
• Mutagenic fingerprint of ozone in human cells
• Opposite base specificity in excision of pyrimidine ring-opened 1,N6-ethenoadenine by thymine glycol DNA-glycosylases
• Polymerase and p53 jointly regulate cell survival, apoptosis and Mre11 recombination during S phase checkpoint arrest after UV irradiation
• Polymorphisms in the human xeroderma pigmentosum group A gene and their impact on cell survival and nucleotide excision repair
• pro-apoptotic dual-role proteins in five major DNA repair pathways
• Ray and hydrogen peroxide induction of gene amplification in hamster cells deficient in DNA double strand break repair
• Reflections on the 8th International Conference on Environmental Mutagens
• Repair of 8-oxoG is slower in endogenous nuclear genes than in mitochondrial DNA and is without strand bias
• Suppression of a DNA double-strand break repair gene, Ku70
• The A rule revisited-polymerases as determinants of mutational specificity
• The formation of UV-induced chromosome aberrations involves ERCC1 and XPF but not other nucleotide excision repair genes
• Transcription coupled repair efficiency determines the cell cycle progression and apoptosis after UV exposure in hamster cells
• Ultraviolet-sensitive syndrome cells are defective in transcription-coupled repair of cyclobutane pyrimidine dimers
• UV damage, DNA repair and skin carcinogenesis
• Xeroderma pigmentosum complementation group E and UV-damaged DNA-binding protein

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• Stem cell biology and gene therapy-
• Adult bone marrow stem cells for cell and gene therapies
• Building a consensus regarding the nature and origin of mesenchymal stem cells
• Cytokine and chemokine networks influencing stem cell proliferation, differentiation, and marrow homing
• Hematopoietic stem cell gene therapy for inherited bone marrow disorders
• Interleukin 17-An example for gene therapy as a tool to study cytokine mediated regulation of hematopoiesis
• Mesenchymal stem cells-Will they have a role in the clinic
• Molecular basis of co-targeting prostate tumor and stroma
• Obstacles to human hematopoietic stem cell transduction by recombinant adeno-associated virus 2 vectors
• Post-transduction events in retrovirus-mediated gene therapy involving hematopoietic stem cells
• Recent advances in and therapeutic potential of muscle-derived stem cells
• Regulatory issues in cellular therapies
• Stem cell plasticity and blood and marrow transplantation
• Stem cells-A minireview
• Stem cells and the philosopher's stone
• Stem cell and gene therapy-
• Adult bone marrow stem cells for cell and gene therapies
• Building a consensus regarding the nature and origin of mesenchymal stem cells
• Cytokine and chemokine networks influencing stem cell proliferation, differentiation, and marrow homing
• Hematopoietic stem cell gene therapy for inherited bone marrow disorders
• Interleukin 17-An example for gene therapy as a tool to study cytokine mediated regulation of hematopoiesis
• Mesenchymal stem cells-Will they have a role in the clinic
• Molecular basis of co-targeting prostate tumor and stroma
• Obstacles to human hematopoietic stem cell transduction by recombinant adeno-associated virus 2 vectors
• Post-transduction events in retrovirus-mediated gene therapy involving hematopoietic stem cells
• Recent advances in and therapeutic potential of muscle-derived stem cells
• Regulatory issues in cellular therapies
• Stem cell plasticity and blood and marrow transplantation-A clinical strategy
• Stem cells and the philosopher's stone
• Stem cells

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• Chemoreflex responses to CO2
• Physiological and Genomic Consequences of Intermittent Hypoxia
• Adaptive responses of skeletal muscle to intermittent hypoxia
• Altered vascular reactivity in arterioles of chronic intermittent hypoxic rats
• Improved anoxic tolerance in rat diaphragm following intermittent hypoxia
• Intermittent hypoxia and respiratory plasticity
• Osteocytes upregulate HIF-1 in response to acute disuse and oxygen deprivation
• Oxygen sensing during intermittent hypoxia-cellular and molecular mechanisms
• Phrenic long-term facilitation requires 5-HT receptor activation
• Physiological consequences of intermittent hypoxia-systemic blood pressure
• Pulmonary hypertension in mice following intermittent hypoxia
• Regulation of sleep-in response to intermittent hypoxic stimuli applied only in sleep
• Respiratory plasticity following intermittent hypoxia
• Role of spleen emptying in prolonging apneas in humans
• Variation in acute hypoxic ventilatory response is linked to mouse chromosome 9

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• Is Periventricular Leukomalacia an Axonopathy as Well as an Oligopathy
• An Educational Program for Patients with Epilepsy and Their Relatives
• Assessment of Quality of Life in People with Epilepsy
• Cell Death and Synaptic Reorganizations Produced by Seizures
• Channelopathies-Episodic Disorders
• Concerns with Antiepileptic Drug Initiation-Safety, Tolerability, and Efficacy
• Efficacy of Levetiracetam
• Pharmacokinetic Considerations in Prescribing Antiepileptic Drugs
• Epileptic Encephalopathy
• Evidence based management of seizures associated with fever
• GABAergic Mechanisms in Epilepsy
• Genetics of the epilepsies
• Interactions Between Hormones and Epilepsy
• Interictal Discharges Promote or Control Seizures
• Issues in the Treatment of Epilepsy
• Levetiracetam-The Preclinical Profile of a New Class of Antiepileptic Drugs
• nvolvement of the Thalamocortical System in Epileptic Loss of Consciousness
• Potassium Channels-Epileptic to New Therapeutic Targets and Drugs
• Principles in Pharmacogenetics
• TGuidelines for Essential Services, Personnel, and Facilities in Specialized Epilepsy Centers in the United States
• The Management of Refractory Idiopathic Epilepsies
• Tiagabine in Clinical Practice
• A pharmacological link between epilepsy and anxiety
• A systematic review of the safety profile of levetiracetam-a new antiepileptic drug,
• Advances in the genetics of progressive myoclonus epilepsy
• Antiepileptic drugs as independent predictors of plasma total homocysteine levels
• Chromosome imbalances associated with epilepsy
• Do we need any more new antiepileptic drugs
• Epilepsy and genetic malformations of the cerebral cortex
• Future directions for epilepsy research
• Genes and mutations in idiopathic epilepsy
• Genetic and environmental factors in epilepsy
• Genetics of the Epilepsies
• IDENTIFICATION OF EPILEPSY GENES IN HUMAN AND MOUSE
• Intractable Epilepsy-Definition and Neurobiology
• Ion channels and epilepsy
• Life-threatening adverse events of antiepileptic drugs
• Managing epilepsy in young women
• Modeling Human Epilepsies in Mice
• Neuropsychology of Epilepsy
• Pharmacogenetics and Antiepileptic Drugs
• Predisposed Susceptibility and Partial Seizure Disorder
• Presurgical evaluation of epilepsy
• Progress in the Genetics of the Partial Epilepsies
• Rearrangements of chromosome 15 in epilepsy
• Review of treatment options for refractory epilepsy
• The genetics of epilepsy
• The Neurobiology and Consequences of Epilepsy in the Developing Brain
• The mechanisms of action of commonly used antiepileptic drugs
• Advances in the genetics of progressive myoclonus epilepsy
• Chromosome imbalances associated with epilepsy
• Epilepsy and genetic malformations of the cerebral cortex
• Genes and mutations in idiopathic epilepsy
• Ion channels and epilepsy
• Rearrangements of chromosome 15 in epilepsy
• Current status and future directions in the pharmacotherapy of epilepsy
• Mossy cells in epilepsy
• Current status and future directions in the pharmacotherapy of epilepsy
• Mossy cells in epilepsy

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Genetically engineered foods

• GENETICALLY ENGINEERED FOODS-
• Phosphomannose Isomerase, a Novel Plant Selection System
• Prediction of Allergenicity of Gene-Modified Foods by Serum-Based Testing
• Protein Allergenicity in Mice
• Protein Body Effect and Other Aspects of Food Matrix Effects
• Sequence Analysis for Assessing Potential Allergenicity
• The Dog as a Model for Food Allergy
• Where Do We Go from Here-A Discussion Summary
• Application of the IFBC-ILSI Allergenicity Assessment Decision Tree
• Assessment of Protein Allergenicity
• Current Understanding of Cross-Reactivity of Food Allergens and Pollen
• Current Understanding of Food Allergens
• Current Understanding of Food Allergy
• Current Understanding of Gastrointestinal Immunoregulation and Its Relation to Food Allergy
• Digestion Stability as a Criterion for Protein Allergenicity Assessment
• Food Allergy Animal Models

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Transcriptome

• Transcriptome and Proteome Analysis in Human Senescent Fibroblasts and Fibroblasts
• APPLICATION OF DNA-CHIP TECHNOLOGY IN THE STUDY OF TRANSCRIPTOME CHANGES IN RHEUMATOID ARTHRITIS
• Tantalizing Transcriptomes-SAGE and Its Use in Global Gene Expression Analysis
• Transcriptome meets metabolome
• Transcriptome of a mouse kidney cortical collecting duct cell line
• GETools-gene expression tool for analysis of transcriptome experiments
• Transcriptome-phenotype correlations in the mouse brain
• Proteome, transcriptome and genome
• Transcriptomes and cellular programs
• Transcriptomes, transcription activators and microarrays
• Analysing uncharted transcriptomes with SAGE
• Analysis of the yeast transcriptome with structural and functional categories
• Circadian Cycling of the Mouse Liver Transcriptome
• Combined transcriptome and proteome analysis as a powerful approach to study genes under glucose repression
• Discovering altered genomic expression patterns in heart-transcriptome determination by serial analysis of gene expression
• Gene expression profiling using a novel method-amplified differential gene expression (ADGE)
• gene locus maps for transcriptome analysis
• Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma
• Large-scale analysis of the human and mouse transcriptomes
• Navigating the human transcriptome
• Profiling the adult human liver transcriptome
• The Genexpress IMAGE Knowledge Base of the Human Muscle Transcriptome
• The Human Transcriptome Map
• The Mouse Brain Transcriptome by SAGE
• Transcript quantitation in total yeast cellular RNA using kinetic PCR
• Yeast Upf Proteins Required for RNA Surveillance Affect Global Expression of the Yeast Transcriptome

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Artificial Chromosome

• Artificial Chromosomes-Coming to Life
• Active Role of a Human Genomic Insert in Replication of a Yeast Artificial Chromosome
• Assembly of large genomic segments in artificial chromosomes by homologous recombination
• Construction of neocentromere-based human minichromosomes by telomere-associated chromosomal truncation
• Genomic and Genetic Definition of a Functional Human Centromere
• Highly Regulated Cell Type-restricted Expression of Human Renin in Mice Containing 140-or 160-Kilobase Pair P1 Phage Artificial Chromosome Transgenes
• Human artificial chromosomes generated by modification of a yeast artificial chromosome containing both human alpha satellite and single-copy DNA sequences
• Neocentromeres and human artificial chromosomes
• Novel generation of human satellite DNA-based artificial chromosomes in mammalian cells
• Stable gene expression from a mammalian artificial chromosome

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nuclear and gene expression

• A year dominated by histone modifications, transitory and remembered
• Biotechnologies and therapeutics-chromatin as a target
• Breaking through to the other side-silencers and barriers
• ChIPs of the |?-globin locus-unraveling gene regulation within an active domain
• Chromatin and transcription
• Chromatin elongation factors
• Chromosomes and expression mechanisms
• Coactivators in transcription initiation-here are your orders
• Deciphering gene expression regulatory networks
• DNA replication and chromatin
• Gene silencing, cell fate and nuclear organisation
• Heterochromatin-new possibilities for the inheritance of structure
• Histone H2A variants H2AX and H2AZ
• Histone methylation in transcriptional control
• Histone modifications in transcriptional regulation
• Programming off and on states in chromatin-mechanisms of Polycomb and trithorax group complexes
• Protein dynamics in the nuclear compartment
• RNAi-nature abhors a double-strand
• X-chromosome inactivation and the search for chromosome-wide silencers

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Functional genomics of sleep and circadian rhythms

• How sleep deprivation affects gene expression in the brain
• Genioglossus muscle activity at rest and in response to brief hypoxia
• Functional genomics of sleep and circadian rhythms
• A neural clockwork for encoding circadian time
• Influence of genioglossus tonic activity on upper airway dynamics assessed by phrenic nerve stimulation

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基因组

• Remarks at the Human Genome Announcement
• Ecogenetics, pharmacogenetics, and complex genetic disease: from Toll to Toll-House
• How to map a gene
• Weeding out the genes: the Arabidopsis genome project
• Functional analysis of the yeast genome
• The target hypothesis as a "quantum leap" to gene mutations
• The low-density lipoprotein receptor gene family: multiple roles in lipid metabolism
• The Mutation Rate and Cancer
• Genomics meets genetics: towards a mutant map of the mouse
• Assessing reliability of gene clusters from gene expression data
• Constraint structure analysis of gene expression
• A New Statistic for Detecting Genetic Differentiation
• Combining structural genomics and enzymology
• Estimate of the Mutation Rate per Nucleotide in Humans
• Horizontal gene transfer among microbial genomes- new insights from complete genome analysis
• Models of protein sequence evolution and their applications
• Ribonucleotide reductases- the link between an RNA and a DNA world
• Genomes and evolution
• genomes-The new phylogeny of eukaryotes
• The Drosophila genome
• The yeast  on the road to the Golden Age
• wide protein interaction maps using two-hybrid systems
• A patent strategy for genomic and research tool patents
• GENOME GYMNASTICS - UNIQUE MODES OF DNA EVOLUTION AND PROCESSING IN CILIATES
• Societal and Medical Consequences of the Human Genome Project
• Comparison of functional annotation schemes for genomes
• Constraint structure analysis of gene expression
• Functional analysis of the yeast genome
• Mitochondrial genome variation and the origin of modern humans
• Relating Genomic Research to Patient Care
• Remarks at the Human Genome Announcement
• Human evolution- A start for population genomics
• Social responsibility in human genetics - a survey
• Weeding out the genes- the Arabidopsis genome project
• Regulation of Genetic Testing in the Human Genome Era
• BACking up the promises
• Chipping away at the human transcriptome
• The end of all human DNA maps
• Variation is the spice of life
• Animal research in the post-genome era
• Comparative genomics- the key to understanding the human genome project
• Instrumentation for the Genome Project
• Retrotransposons as epigenetic mediators of phenotypic variation in mammals
• The human genome, in proportion
• Sequence and analysis of the Arabidopsis genome
• ASSOCIATION STUDY DESIGNS FOR COMPLEX DISEASES
• After the DNA and Human Disease
• ANCIENT ORIGIN OF THE HOX GENE CLUSTER
• At the interfaces of epidemiology, genetics and genomics
• CHROMOSOMAL STABILITY AND THE DNA DOUBLE-STRANDED BREAK CONNECTION
• FUNCTION AND EVOLUTION OF THE PLANT MADS-BOX GENE FAMILY
• Functional analysis of the yeast genome
• Gene silencing
• GENETIC DISSECTION OF PHENOTYPIC DIVERSITY IN FARM ANIMALS
• GENOMIC IMPRINTING- PARENTAL INFLUENCE ON THE GENOME
• GENOMIC STRATEGIES TO IDENTIFY MAMMALIAN REGULATORY SEQUENCES
• GLIOMAGENESIS- GENETIC ALTERATIONS AND MOUSE MODELS
• Human genome diversity- What about the other human genome project
• Illuminating the human genome
• Mapping a new frontier- development of integrated cytogenetic maps in plants
• MODIFIER GENES IN MICE AND HUMANS
• POST-TRANSCRIPTIONAL GENE SILENCING BY DOUBLE-STRANDED RNA
• QUANTITATIVE TRAIT LOCI IN DROSOPHILA
• REWIRING THE KEYBOARD- EVOLVABILITY OF THE GENETIC CODE
• THE HUMAN Y CHROMOSOME, IN THE LIGHT OF EVOLUTION
• Weeding out the genes- the Arabidopsis genome project
• X-CHROMOSOME INACTIVATION- COUNTING, CHOICE AND INITIATION
• ZEBRAFISH GENETICS AND VERTEBRATE HEART FORMATION

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功能基因组

• Exploring genome space
• Four years of post-genomic life with 6000 yeast genes
• gene expression profiling: monitoring transcription and translation products using DNA microarrays and proteomics
• Genomics, gene expression and DNA arrays
• Protein function in the post-genomic era
• Proteomics to study genes and genomes
• Automated extraction of information in molecular biology
• Convergent evolution with combinatorial peptides
• Domain repertoires as a tool to derive protein recognition rules
• Gene expression data analysis
• Gene trap: a way to identify novel genes and unravel their biological function
• Recent developments and future directions in computational genomics
• The role of protein structure in genomics
• wide protein interaction maps using two-hybrid systems
• p53: Death Star
• Functional genomics by mass spectrometry
• Molecular evolution of the growth hormone-releasing hormone/pituitary adenylate cyclase
• Functional genomics reveals a family of eukaryotic oxidation protection genes
• Key strategies in functional genomics for drug discovery

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结构基因组

• An integrated approach to structural genomics
• Methodologies for target selection in structural genomics
• Structural genomics projects in Japan
• Structural genomics
• Structural proteomics- prospects for high throughput sample preparation
• structure genomics-Towa