Antibody 2001

    
    单克隆抗体的制备和应用是近年来医学生物学的一个突出成绩.应用抗体诊断和治疗一些疑难重症已经成为21世纪医药发展的一个重要方向.近年来已经取得飞速发展.抗体工程已经成为当前生物高技术竞争的一个重要方面.本专题收集了2001年发表的60余篇综述,供参考.更多内容,亦可查询CMBI-REVIEW。
总论

Monoclonal antibody therapies

New aspects of autoantibody detection with a new combination of autoantigenic targets

Immune Responses-Regulation of the Immune Response by Antigen

New approaches to dissect degeneracy and specificity in T cell antigen recognition

Structural chemistry and therapeutic intervention of protein-protein interactions

Camel Single-domain Antibodies as Modular Building Units in Bispecific and Bivalent Antibody Constructs

IgA and the IgA Fc receptor

CRITICAL ANALYSIS OF ANTIBODY CATALYSIS

Therapy of B-cell lymphomas with monoclonal antibodies and radioimmunoconjugates

A novel antibiotic target-drug

the coming of age of radioimmunotherapy

antibodies as next generation therapeutics

Role of radiation dosimetry in radioimmunotherapy planning and treatment dosing

Antibody arrays for high-throughput screening of antibody-antigen interactions

'Anticalins': a new class of engineered ligand-binding proteins with antibody-like properties

Susceptibility of B-cell lymphoma to human antibodies encoded by the V4-34 gene

ANTIBODY ENGINEERING

IGG FC RECEPTORS

A Touch of Antibody Class

抗体产生

Immunomodulatory therapy of human type 1 diabetes

Complex layers of genetic alteration in the generation of antibody diversity

In vivo activity in a catalytic antibody-prodrug system

Generation of Sequence-specific, High Affinity Anti-DNA Antibodies

High-throughput generation and engineering of recombinant human antibodies

Biotechnological applications of phage and cell display

Cosmix-plexing- a novel recombinatorial approach for evolutionary selection from combinatorial libraries

Immune Responses-rrested Differentiation, the Self-Renewing Memory Lymphocyte, and Vaccination

'Immune Responses-Breeding' Antigens for New Vaccines

Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets

Single domain camel antibodies- current status

In vivo recombination as a tool to generate molecular diversity in phage antibody libraries

A PHAGE DISPLAY APPROACH FOR RABBIT ANTIBODY HUMANIZATION

SPECIFICITY AND DEGENERACY IN ANTIGEN RECOGNITION

DNA Vaccines-Aunology, Application, and Optimization

Recognition of antigens by single-domain antibody fragments

IL-10 and its homologs- important immune mediators and emerging immunotherapeutic agents

Regulation of Antibody Responses via Antibodies, Complement, and Fc Receptors

Immunomodulators and delivery systems for vaccination by mucosal routes

Estrogen receptor antibodies

Immune Responses-Immune Control, Memory, and Vaccines

A human myeloma cell line suitable for the generation of human monoclonal antibodies

Antibacterial vaccine design using genomics and proteomics

Antigen Specificity and High Affinity Binding Provided by One Single Loop of a Camel Single-domain Antibody

肿瘤治疗

Cancer vaccines based on dendritic cells loaded with tumor-associated antigens

Antibody-Ccytokine fusion proteins for the therapy of cancer

Creating therapeutic cancer vaccines

Preclinical and clinical data with bispecific antibodies recruiting myeloid effector cells for tumor therapy

IgA antibodies for cancer therapy

Design and application of diabodies, triabodies and tetrabodies for cancer targeting

Vaccines in urologic malignancies

Development of ABX-EGF, a fully human anti-EGF receptor monoclonal antibody, for cancer therapy

Immune-Boosting Drug Could Help Cancer Patients

Immunotherapy for colorectal cancer

Antibody therapy for residual disease in acute myelogenous leukemia

Ribosome display and affinity maturation- from antibodies to single V-domains and cancer therapeutics

Trastuzumab, Monoclonal Antibody for the Treatment of Breast Cancer -drug

The Emerging Role Of Radioimmunotherapy In Haematological Malignancies

Strategies for cancer therapy using carcinoembryonic antigen vaccines

Clinical approaches to vaccination in oncology

The promise of monoclonal antibodies for the therapy of cancer

Tumour vaccines- a new immunotherapeutic approach in oncology

Successful therapy of a human lung cancer xenograft using MAb RS7 labeled with residualizing radioiodine

Localization of pancreatic cancer with radiolabeled monoclonal antibody PAM4

Anti-idiotypic antibody and recombinant antigen vaccines in colorectal cancer patients

传染病治疗

Challenges in the Development of an Effective HIV Vaccine

Hepatitis B vaccines

Epitopes Involved in Antibody-Mediated Protection from Ebola Virus

ADVANCES IN THE TREATMENT OF LUPUS NEPHRITIS

TB vaccines- progress and problems

RNA Editing AIDs Antibody Diversification

Control of a Mucosal Challenge and Prevention of AIDS by a Multiprotein DNA-MVA Vaccine

AIDS Vaccines Show Promise After Years of Frustration

Protection of a pathogenic HIV-1-SIV chimeric virus by passive infusion of neutralizing antibodies

Helicobacter pylori vaccines-the current status

Progress in vaccination against Helicobacter pylori

其它治疗

Treatment of B-cell non-Hodgkin's lymphoma with anti CD 20 monoclonal antibody Rituximab

ANTIBODY-TARGETED IMMUNOTHERAPY FOR TREATMENT OF MALIGNANCY

ANTI-TNF THERAPY OF RHEUMATOID ARTHRITIS

Monoclonal antibody therapy for Crohn-rsquos disease

Monoclonal antibody strategies to block angiogenesis

Immunomodulatory therapy of human type 1 diabetes

Recent advances in antigen-targeted therapy in non-Hodgkin's lymphoma

Principles and practice of antibiotic therapy of diabetic foot infections

the clinical role of anti-TNFa antibody treatment in Crohn's disease

其它

Antibodies with infinite affinity

Contribution of Receptor Editing to the Antibody Repertoire

Antinuclear antibodies (ANA) Diagnostic value of different methods for screening and differentiation

Targeting of Functional Antibody-Decay-accelerating Factor Fusion Proteins to a Cell Surface


更新于2001-08-08