computational genetics



computational genetics
人类基因组计划的实施使得计算机、信息科学在生物学与医学的研究中显示出日益重要的地位。它的作用不仅仅在于基因拼接、查询，蛋白质的结构、功能的预测，它可以在此基础上为生物学、医学作出更为突出的贡献。计算机信息科学已经成为现代各个学科普遍使用的一个工具，大大推动了各个学科的发掌。现在各国的生物学家、医学家对于计算机信息科学以后在生物学和医学中的作用都有一些十分超前的展望，以下是CMBI从各种期刊上摘录的有关computational genetics的文献，其中包括了计算机信息科学业已涉及的各个方面，也对计算机信息科学还未涉及的几个方面做了十分令人兴奋的展望。希望可以对广大的生物学医学工作者有所触动和帮助。
Computing an organism Whole-cell simulation- a grand challenge of the 21st century A literature network of human genes BIOINFORMATICS BEYOND SEQUENCE- MAPPING GENE FUNCTION IN THE COMPUTATIONAL ANALYSIS OF MICROARRAY DATA COMPUTATIONAL STUDIES OF GENE REGULATORY NETWORKS Computer-based three dimensional visualization of developmental gene expression EVOLUTIONARY COMPUTATION GENOMIC STRATEGIES TO IDENTIFY MAMMALIAN REGULATORY SEQUENCES In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data Linking microarray data to the literature Making the most of microarray data. Mining the draft human genome New computation approaches for functional genomics Protein function in the post genomic era. The origins of bioinformatics A Challenge for Bioinformatics and Post-Genome BIOINFORMATICS TOOLS FOR WHOLE GENOMES Computational comparison of two draft sequences of the human genome Evolving design genes in space layout planning problems Four years of post-genomic life with 6000 yeast genes Molecular Computation by DNA Hairpin Formation Monte Carlo Markov chain methods and model selection in genetic epidemiology The modularity of biological regulatory networks Using bioinformatics in gene and drug discovery

更新于2001-07-12