干细胞与心肌修复



干细胞与心肌修复
心肌梗死、心力衰竭、脑卒中一直是困扰人类的危险性疾病，以前认为这些疾病引起的破坏是不可逆的，现在由于干细胞技术的出现与成熟，人们在这一领域取得了前所未有的进步，使得人类可以逐步的脱离这些疾病的困扰。Nature、Science、Cell、AHA等杂志对此都有相关的报道，各大媒体网站也有一定的关注。以下一些文章介绍了近一年来国际上干细胞技术的发展以及在运用干细胞技术治疗心血管疾病所取得的成果，供国内心血管医学界的研究人员进行参考。
媒体报道关于胚胎干细胞研究的争论 (CMBI评论员李黔) 干细胞移植治疗心肌损伤 (CMBI评论员李黔) Cell regrowth may be enough to mend hearts Study Finds Heart Muscle Regenerates After Attack Heart-Cells Discovery Gives Hope Study Heart Cells Could Repair Damaged Hearts Arm Cells Used in Attempt to Heal Heart LA Times Can Skeletal Muscle Replace Damaged Heart Muscle Potential Heart Disease Treatment Identified MD Puts Arm Muscle Cells Into Heart Stem-Cell Therapy To Restore Cardiac Function On The Horizon 相关文献 New tools for human developmental biology Regulatory Mechanisms in Stem Cell Biology Stem cell transplantation in utero for genetic diseases Chimeric stem cells Stem Cells: A New Lease on Life Stem Cells and Their Niches Stem cells get to the heart of the matter Stem Cells: Units of Development, Units of Regeneration, and Units in Evolution Stem Cell Technology for Basic Science and Clinical Applications the unexpected sources of tissue regeneration The biology of stem cell factor Varmus Proposes Guidelines for Stem Cell Research The politics and ethics of human embryo and stem cell research CYTOKINE RECEPTOR SIGNAL TRANSDUCTION AND THE CONTROL OF HEMATOPOIETIC CELL DEVELOPMENT Dystrophin expression in the mdx mouse restored by stem cell transplantation 　 New Potential for Human Embryonic Stem Cells A Role for Hematopoietic Stem Cells in Promoting Angiogenesis Bioengineered Cardiac Grafts - A New Approach to Repair the Infarcted Myocardium cardiomyocyte differentiation of embryonic stem cells Development of Endothelial Cell Lines From Embryonic Stem Cells Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells Genetically selected cardiomyocytes from differentiating embryonic stem cells form stable intracardiac grafts In vitro Differentiation of Genetically Engineered Embryonic Stem Cells into Cardiac Cells Multilineage Differentiation from Human Embryonic Stem Cell 　 Bone marrow cells regenerate infarcted myocardium bone marrow derived endothelial progenitor cells for neovascularization Multi-Organ, Multi-Lineage Engraftment by a Single Bone Marrow-Derived Stem Cell Muscle regeneration by bone marrow-derived myogenic progenitors Neovascularization of ischemic myocardium by human bone-marrow¨Cderived angioblasts 　 Blood-derived angioblasts accelerate blood-flow restoration Exogenous Hematopoietic Stem Cells Can Regenerate Infarcted Myocardium Functional activity of murine CD34+ and CD34- hematopoietic stem cell populations Gene correction in hematopoietic progenitor cells by homologous recombination Hematopoietic potential of stem cells isolated from murine skeletal muscle Hematopoietic Stem Cell Transplantation Hematopoietic stem cells- old and new Hematopoietic stem cells In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells Interest of cord blood stem cells Isolation of putative progenitor endothelial cells for angiogenesis MEKK1 suppresses oxidative stress-induced apoptosis of embryonic stem cell-derived cardiac myocytes Purified hematopoietic stem cells can differentiate into hepatocytes in vivo Self renewal, differentiation or death-regulation and manipulation of hematopoietic stem cell fate Standardization of hematopoietic stem cell meeting sponsored by the National Heart The Role of Cytokines and Adhesion Molecules for Mobilization of Peripheral Blood Stem Cells 　 Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors Cell Transplantation as Future Therapy for Cardiovascular Disease mooth Muscle Cell Transplantation into Myocardial Scar Tissue Improves Heart Function MYOBLAST CELL GRAFTING INTO HEART MUSCLE Myocyte Enhancer Factor 2C and Nkx2-5 Up-regulate Each Other's Expression and Initiate Cardiomyogenesis in P19 Cells Myocyte proliferation in end-stage cardiac failure in humans Myogenic stem cells for the therapy of primary myopathies Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells Stem Cell Factor in Mast Cells and Increased Mast Cell Density in Idiopathic and Ischemic Cardiomyopathy Stem Cell Factor Induction Is Associated With Mast Cell Accumulation After Canine Myocardial Ischemia and Reperfusion


更新于2001-06-08