Immunology of Diabetes


    糖尿病是一组常见的代谢内分泌病,分原发性及继发性两类。常见的有胰岛素依赖型(IDDM,Ⅰ型)和非胰岛素依赖型(NIDDM,Ⅱ型),糖尿病的病因复杂,一直是世界糖尿病研究的重要课题。但目前已肯定自身免疫与Ⅰ型患者关系密切,人体内存在某些抗原其化学和构成和β细胞酷似,则该抗原产生的抗体也将针对β细胞发动免疫攻击,导致β细胞严重破坏。已发现了很多Ⅰ型糖尿病患者细胞和体液免疫的证据。而且近几年研究发现糖尿病并发症的发病机理也和免疫有关,为了方便读者更多的了解糖尿病免疫方面的相关知识,现将搜集到的文献列举如下,更多的文献请查阅cmbi的综述查询和相关栏目:

IMMUNOLOGY OF DIABETES-iabetes-Related Autoantibodies in Cord Blood from Children of Healthy Mothers Have Disappeared

IMMUNOLOGY OF DIABETES-Antibodies to New Beta Cell Antigen ICA12 in Latvian Diabetes Patients

IMMUNOLOGY OF DIABETES-Anti-Insulin-like Growth Factor-1 Autoantibodies in Type 1 Diabetes

IMMUNOLOGY OF DIABETES-Apoptosis of Autoreactive CD8 Lymphocytes as a Potential Mechanism for the Abrogation of Type 1 Diabetes by Islet-Specific TNF-Expression

IMMUNOLOGY OF DIABETES-Autoantibodies and HLA Susceptibility Markers in Canadian First-Degree Relatives of Patients with Type 1 Diabetes

IMMUNOLOGY OF DIABETES-Autoantibodies to IA-2 in Type 1 Diabetes-Measurements with a New Enzyme-Linked Immunosorbent Assay

IMMUNOLOGY OF DIABETES-Autoantibodies to Tissue Transglutaminase in Patients from Eastern India with Malnutrition-Modulated Diabetes Mellitus

IMMUNOLOGY OF DIABETES-Autoimmune Diabetes in 26 Villages outside Madras

IMMUNOLOGY OF DIABETES-BCG Vaccination and GAD65 and IA-2 Autoantibodies in Autoimmune Diabetes in Southern India

IMMUNOLOGY OF DIABETES-Contribution of MIC-A Polymorphism to Type 1 Diabetes Mellitus in Basques

IMMUNOLOGY OF DIABETES-Corticosteroid-Responsive Diabetes Mellitus Associated with Autoimmune Pancreatitis

IMMUNOLOGY OF DIABETES-CTLA-4 Gene Polymorphism Contributes to the Genetic Risk for Latent Autoimmune Diabetes in Adults

IMMUNOLOGY OF DIABETES-Dendritic Cell-Based Proliferative Assays of Peripheral T Cell Responses to Tetanus Toxoid

IMMUNOLOGY OF DIABETES-Diabetes Prevention Trial 1

IMMUNOLOGY OF DIABETES-Distinct IA-2 Autoantibody Epitope Recognition between Childhood-Onset and Adult-Onset Type 1 Diabetes

IMMUNOLOGY OF DIABETES-DR3 Is Associated with Type 1 Diabetes and Blood Group ABO Incompatibility

IMMUNOLOGY OF DIABETES-Fas Stimulation Results in Selective Islet Infiltrate Apoptosis in Situ and Reversal of Diabetes

IMMUNOLOGY OF DIABETES-GAD65 and ICA512 Antibodies in Undernourished and Normally Nourished South Indian Patients with Diabetes

IMMUNOLOGY OF DIABETES-Genetic Dissection of Type 1 Diabetes Susceptibility Gene, Idd3, by Ancestral Haplotype Congenic Mapping

IMMUNOLOGY OF DIABETES-HLA-DRB1, DQB1, and DQA1 Allele Profile in Brazilian Patients with Type 1 Diabetes Mellitus

IMMUNOLOGY OF DIABETES-IA View on Beta Cell Transplantation in Diabetes

IMMUNOLOGY OF DIABETES-IAntidiabetogenic Effect of Mycophenolate Mofetil Is Associated with Down-Regulation of Adhesive Interactions and Autoreactive Cell Activation

IMMUNOLOGY OF DIABETES-IAntiinfection Immunity and Autoimmunity

IMMUNOLOGY OF DIABETES-IAutoantibody Profile and Epitope Mapping in Latent Autoimmune Diabetes in Adults

IMMUNOLOGY OF DIABETES-IBeta Cell Rest and Recovery—Does It Bring Patients with Latent Autoimmune Diabetes in Adults to Euglycemia

IMMUNOLOGY OF DIABETES-ICA12 Autoantibodies Are Associated with Non-DR3-Non-DR4 in Patients with Latent Autoimmune Diabetes

IMMUNOLOGY OF DIABETES-IClinicoepidemiological and Biochemical Profile of Malnutrition-Modulated Diabetes Mellitus

IMMUNOLOGY OF DIABETES-IGenetics of Latent Autoimmune Diabetes in Adults

IMMUNOLOGY OF DIABETES-IImmunogenetic Studies on Malnutrition-Modulated Diabetes Mellitus

IMMUNOLOGY OF DIABETES-IInsulin Intervention to Preserve ? Cells in Slowly Progressive Insulin-Dependent (Type 1) Diabetes Mellitus

IMMUNOLOGY OF DIABETES-IL-1? Expression in Islet Cells of the NOD Mouse and Its Spatial Relationship to Beta Cells and Inducible Nitric Oxide Synthase

IMMUNOLOGY OF DIABETES-ILatent Autoimmune Diabetes in Adults

IMMUNOLOGY OF DIABETES-Immunogenetics of Autoimmune Diseases in Asian Indians

IMMUNOLOGY OF DIABETES-IMolecular Mechanisms Involved in the Etiopathogenesis of Malnutrition-Modulated Diabetes Mellitus

IMMUNOLOGY OF DIABETES-Increased Autoantibodies to SOX13 in Swedish Patients with Type 1 Diabetes

IMMUNOLOGY OF DIABETES-Induction of Donor-Specific Tolerance to Islet Allografts in Nonhuman Primates

IMMUNOLOGY OF DIABETES-Induction of Insulin Autoantibodies and Protection from Diabetes with Subcutaneous Insulin B-9-23 Peptide without Adjuvant

IMMUNOLOGY OF DIABETES-Induction of Islet Allotolerance in Nonhuman Primates

IMMUNOLOGY OF DIABETES-International Workshop on Lessons from Animal Models for Human Type 1 Diabetes

IMMUNOLOGY OF DIABETES-IOral Tolerance, Systemic Immunoregulation, and Autoimmunity

IMMUNOLOGY OF DIABETES-IRegulatory Natural Killer T Cells Protect against Spontaneous and Recurrent Type 1 Diabetes

IMMUNOLOGY OF DIABETES-Islet Autoantibodies in Latvian Subjects with Non-Insulin-Dependent Diabetes Mellitus

IMMUNOLOGY OF DIABETES-IThe Gut Immune System and Type 1 Diabetes

IMMUNOLOGY OF DIABETES-ITheiler's Virus-Mediated Autoimmunity

IMMUNOLOGY OF DIABETES-IUse of In Vitro-Generated, Stem Cell-Derived Islets to Cure Type 1 Diabetes

IMMUNOLOGY OF DIABETES-IViruses and Diabetes

IMMUNOLOGY OF DIABETES-MHC Class I Chain-Related Gene A Alleles Distinguish Malnutrition-Modulated Diabetes, Insulin-Dependent Diabetes, and Non-Insulin-Dependent Diabetes Mellitus

IMMUNOLOGY OF DIABETES-MHC Class I Chain-Related Gene Alleles 5 and 5.1 Are Transmitted More Frequently to Type 1 Diabetes Offspring in HBDI Families

IMMUNOLOGY OF DIABETES-Microsatellite Allele 5 of MHC Class I Chain-Related Gene A Increases the Risk for Insulin-Dependent Diabetes Mellitus

IMMUNOLOGY OF DIABETES-Microsatellite Allele A5.1 of MHC Class I Chain-Related Gene A Is Associated with Latent Autoimmune Diabetes

IMMUNOLOGY OF DIABETES-Molecular Mimicry in Type 1 Diabetes

IMMUNOLOGY OF DIABETES-Newborn Screening for High-Risk Human Leukocyte Antigen Markers Associated with Insulin-Dependent Diabetes Mellitus

IMMUNOLOGY OF DIABETES-Pancreatic Autoantibodies in Italian Patients with Newly Diagnosed Type 1 Diabetes Mellitus under the Age of 20 Years

IMMUNOLOGY OF DIABETES-Prevalence of ICA-12 and Other Autoantibodies in North Indian Patients with Early-Onset Diabetes

IMMUNOLOGY OF DIABETES-Relation between Course of Disease in Type 1 Diabetes and Islet Cell Antibodies

IMMUNOLOGY OF DIABETES-Role of Donor MHC Class III Genes in the Destruction of Transplanted Islets in NOD Mice

IMMUNOLOGY OF DIABETES-Th2 Dominance of T Helper Cell Response to Preproinsulin in Individuals with Preclinical Type 1 Diabetes

IMMUNOLOGY OF DIABETES-The Combination of Several Polymorphic Amino Acid Residues in the DQ and DQ? Chains Forms a Domain Structure Pattern and Is Associated with Insulin-Dependent Diabetes Mellitus

IMMUNOLOGY OF DIABETES-The Number of Markers of Pancreatic Autoimmunity Is Proportional to the Risk for Type 1 Diabetes Mellitus in Italian and English

IMMUNOLOGY OF DIABETES-The PEVKEK Region of the Pyridoxal Phosphate Binding Domain of GAD65 Expresses a Dominant B Cell Epitope for Type 1 Diabetes Sera

IMMUNOLOGY OF DIABETES-The Role of Fas Ligand in Beta Cell Destruction in Autoimmune Diabetes

IMMUNOLOGY OF DIABETES-Tumor Necrosis Factor-Allele 2 Shows an Association with Insulin-Dependent Diabetes Mellitus

IMMUNOLOGY OF DIABETES-Women Diagnosed with Gestational Diabetes Mellitus Do Not Carry Antibodies against Minor Islet Cell Antigens

IMMUNOLOGY OF DIABETES-Women Diagnosed with Gestational Diabetes Mellitus Do Not Carry Antibodies against Minor Islet Cell Antigens


更新于2002-09-08