Microarray


   微阵列(microarray)或生物芯片技术是随着"人类基因组计划"(HGP)的进展而发展起来的分子生物学里又一项里程碑式的重大技术革新。它是融微电子学、生物学、物理学、化学、计算机科学于一体,通过平面微细加工技术在固相表面构建的微流体分析单元和系统的新技术。其最大优点是:在分析速度成千上万倍提高的同时,所需样品及化学药品却成千上万倍地减少,因而又称为生物芯片技术。目前生物芯片技术包括基因芯片、蛋白质芯片、细胞芯片、组织芯片、以及元件型微阵列芯片、通道型微阵列芯片、生物传感芯片等新型生物芯片。它不仅具有重大的基础研究价值,而且具有明显的产业化前景。下面就将收集到的260多篇 Microarray的相关文献和最新报道奉献给大家,更多的文献请查阅cmbi的综述查询和相关栏目:


proteome-Oligosaccharide microarrays for high-throughput detection and specificity assignments of carbohydrate-protein interactions

cv-genome-DNA Microarrays- Implications for Cardiovascular Medicine

genome-Significance and statistical errors in the analysis of DNA microarray data

genome-Microarray Experiments and Data Analysis

cell-G-Protein-Coupled Receptor Microarrays

microarray-Carbohydrate Microarrays

microarray-DNA array-based method for detection of large rearrangements in the BRCA1 gene

cv-genome-microarray-Changes in gene expression in atherosclerotic plaques analyzed using DNA array

drug discovery-From microarrays to networks- mining expression time series

ageing-Gene expression profiling of aging using DNA microarrays

ca-hepatocellular carcinoma-Analysis of differentially expressed genes in hepatocellular carcinoma using cDNA arrays

ca-Sarcomas-cDNA microarray analysis of global gene expression in sarcomas

cv-genetice-Growth characteristics, angiotensin II generation, and microarray-determined gene expression in VSMC

drug-Enhancing Drug Discovery and Development-Feature extraction and normalization algorithms for high-density oligonucleotide gene expression array data

endocrin-Human Genome on Endocrinology-How to Make Microarray, Serial Analysis of Gene Expression, and Proteomic Relevant to Day-to-Day Endocrine Problems and Physiological Systems

endocrin-Human Genome on Endocrinology-Micoarrays and Differential Display PCR—Tools for Studying Transcript Levels of Genes in Neuroendocrine Systems

endocrin-Human Genome on Endocrinology-Microarray Technology, Seeing More Than Spots

endocrin-Human Genome on Endocrinology-Microarray-Based Expression Profiling of Normal and Malignant Immune Cells

eye-Detection of Differentially Expressed Genes in Healing Mouse Corneas, Using cDNA Microarrays

eye-Molecular Vision-Evaluation and optimization of procedures for target labeling and hybridization of cDNA microarrays

eye-Molecular Vision-The microarray-potential applications for ophthalmic research

genome-Microarrays and polyglutamine disorders

microarray-Global analysis of stress-regulated mRNA turnover by using cDNA arrays

Microarray-Practical Approaches to Analyzing Results of Microarray Experiments

microarrays-Discovery and analysis of hepatocellular carcinoma genes using cDNA microarrays

pathol-Tissue microarrays-a new approach for quality control in immunohistochemistry

proteome-Global and Specific Translational Control by Rapamycin in T Cells Uncovered by Microarrays and Proteomics

reproduction-DNA microarray analyses of genes regulated during the differentiation of embryonic stem cells

surg-DNA microarrays-Revolutionary insight into the living genome

biochem-chembiochem-Carbohydrate Arrays for the Evaluation of Protein Binding and Enzymatic Modification

biochem-chembiochem-Substrate Arrays as Enzyme Fingerprinting Tools

biotech-Previously unrecognized vaccine candidates against group B meningococcus identified by DNA microarrays

biotech-vaccine-candidates against group B meningococcus identified by DNA microarrays

ca-genetics-Gene expression profiling of cancer by use of DNA arrays-how far from the clinic

ca-genome-Defining signal thresholds in DNA microarrays-exemplary application for invasive cancer

cv-genome-Changes in gene expression in atherosclerotic plaques analyzed using DNA array

cv-genome-Microarray analysis of gene expression in vascular smooth muscle cells from spontaneously hypertensive rats at an early age

cv-Microarray analysis of global changes in gene expression during cardiac myocyte differentiation

cv-Microarray gene expression profiles in dilated and hypertrophic cardiomyopathic end-stage heart failure

cv-proteome-Heart failure and apoptosis-Electrophoretic methods support data frommicro-and macro-arrays.A critical review of genomics and proteomics

Genetics-DESIGN ISSUES FOR CDNA MICROARRAY EXPERIMENTS

genome-Empirical characterization of the expression ratio noise structure in high-density oligonucleotide arrays

genome-Microarray profile of differentially expressed genes in a monkey model of allergic asthma

genome-Microarray results-how accurate are they

genome-Model-based cluster analysis of microarray gene-expression data

genome-Normalization and analysis of DNA microarray data by self consistency and local regression

genome-Permutation-validated principal components analysis of microarray data

genome-Physical mapping of genes in somatic cell radiation hybrids by comparative genomic hybridization to cDNA microarrays

medicine-mol-The value of microarray techniques for quantitative gene profiling in molecular diagnostics

mol med-High-throughput protein arrays-prospects for molecular diagnostics

pathol-Obtaining reliable information from minute amounts of RNA using cDNA microarrays

proteome-Adapting arrays and lab-on-a-chip technology for proteomics

proteome-Generating addressable protein microarrays with PROfusion covalent mRNA-protein fusion technology

proteome-Protein based microarray-A tool for probing the proteome of cancer cells and tissues

proteome-Protein microarray technology

proteome-Zeptosens' protein microarrays-A novel high performance microarray platform for low abundance protein analysis

Proteomic profiling of the cancer microenvironment by antibody arrays

microarray-DNA microarrays for assessing ovarian cancer gene expression

microarray-Statistical intelligence- effective analysis of high-density microarray data

microarray-GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways

Microarray technology An array of opportunities

Transcriptomes, transcription activators and microarrays

drug discovery-An array of target-specific screening strains for antibacterial discovery

drug-Combinatorial chemistry-From combinatorial chemistry to chemical microarray

microarray-Selection bias in gene extraction on the basis of microarray gene-expression data

microarray-The complexity of comparing reaction systems

microarrays-OligoArray-genome-scale oligonucleotide design for microarrays

microarray-Mixture modelling of gene expression data from microarray experiments

Microarray-Identification of Myc-mediated Death Response Pathways by Microarray Analysis

microarray-Identification of Genes Downstream of Pax6 in the Mouse Lens Using cDNA Microarrays

microarray-Genesis-cluster analysis of microarray data

microarray-DRAGON View-information visualization for annotated microarray data

microarray-CGO-utilizing and integrating gene expression microarray data in clinical research and data management

microarray-Avoiding cross hybridization by choosing nonredundant targets on cDNA arrays

microarray-Analysis of matched mRNA measurements from two different microarray technologies

Microarray-Analysis of Gene Expression Profile Induced by Hepatocyte Nuclear Factor 4 in Hepatoma Cells Using an Oligonucleotide Microarray

microarray-Adjustments and measures of differential expression for microarray data

microarray-A mixture model-based approach to the clustering of microarray expression data

Microarray technology-An array of opportunities

Microarray data warehouse allowing for inclusion of experiment annotations in statistical analysis

medicine-Complex Disease-Parallel Genotyping of Human SNPs Using Generic High-density Oligonucleotide Tag Arrays

biotech-Array-Based Electrical Detection of DNA with Nanoparticle Probes

genome-Gene expression profile analysis by DNA microarrays-Promise and pitfalls

proteome-Protein microarray technology

biotech-DNA microarrays with stem?§Cloop DNA probes-preparation and applications

microarray-Optical Projection Tomography as a Tool for 3D Microscopy and Gene Expression Studies

respir-Lung Genetics, Genomics, and Gene Therapy-Uses of Expression Microarrays in Studies of Pulmonary Fibrosis, Asthma, Acute Lung Injury, and Emphysema

respir-Lung Genetics, Genomics, and Gene Therapy-Pseudomonas-Epithelial Cell Interactions Dissected With DNA Microarrays

respir-Lung Genetics, Genomics, and Gene Therapy-Oligonucleotide Microarray Analysis of Lung Adenocarcinoma in Smokers and Nonsmokers Identifies GPC3 as a Potential Lung Tumor Suppressor

microarrays-Analysis of cell-cycle-specific gene expression in human cells as determined by microarrays

microarray-Genome-wide detection of chromosomal imbalances in tumors using BAC microarrays

Microarray-Establishing Connections between Microarray Expression Data and Chemotherapeutic Cancer Pharmacology

Microarray Analysis-A Comparative Approach

proteome-Gene expression profiling-monitoring transcription and translation products using DNA microarrays and proteomics

Modulation of Anthracycline-Induced Myofibrillar Disarray in Rat Ventricular Myocytes by Neuregulin-1? and Anti-erbB2 -Potential Mechanism for Trastuzumab-Induced Cardiotoxicity

Maternal Hypercholesterolemia During Pregnancy Promotes Early Atherogenesis in LDL Receptor-Deficient Mice and Alters Aortic Gene Expression Determined by Microarray

imm-microarrays-Autoantigen microarrays for multiplex characterization of autoantibody responses

pathol-Microarrays under the microscope

microarrays-Metabolomics and microarrays for improved understanding of phenotypic characteristics controlled by both genomics and environmental constraints

cv-Hypertension and Metabolic Disarray

cv-cell-Neointima-Gene Expression Profiling of Human Stent-Induced Neointima by cDNA Array Analysis

proteome-Two-hybrid arrays

proteome-perspective on protein microarrays

proteome-Functional protein microarrays

proteome-Emerging array-based technologies in proteomics

proteome-Current achievements using ProteinChip Array technology

proteome-Clinical and functional target validation using tissue and cell microarrays

microarray-Carbohydrate microarrays for the recognition of cross-reactive molecular markers

microarray-Current themes in microarray experimental design and analysis

miocroarry-Model-based analysis of oligonucleotide arrays-model validation, design issues and standard error application

microarry-Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions

microarray-Sources of nonlinearity in cDNA microarray expression measurements

microarrays-Analysis of DNA microarrays using algorithms that employ rule-based expert knowledge

microarray-Cluster-Rasch models for microarray gene expression data

Microarray Analysis-A Comparative Approach

cv-genetics-RNA-Gene expression profile analysis by DNA microarrays

biotech-Analysis of DNA-microarrays produced by inverse in situ oligonucleotide synthesis

bi-Match-Only Integral Distribution (MOID) Algorithm for high-density oligonucleotide array analysis

microArray-Based Electrical Detection of DNA with Nanoparticle Probes

bi-e-cell-Analysis of DNA-microarrays produced by inverse in situ oligonucleotide synthesis

surg-DNA microarrays-Revolutionary insight into the living genome

sc-DNA Array Analysis of CD34 Cells

ca-breast tumor-Characterization of adjacent breast tumors using oligonucleotide microarrays

renal disease-Prospective use of DNA microarrays for evaluating renal function and disease

blood-Leukocytes-Microarrays in hematology

pharmacol-Gene expression microarray analysis in cancer biology, pharmacology, and drug development-progress and potential

pathol-tech-The Developpathol-ment of a Cell Array and Its Combination with Laser-Scanning Cytometry Allows a High-Throughput Analysis of Nuclear DNA Content

pathol-tech-Detection of novel gene expression in paraffin-embedded tissues by isotopic in situ hybridization in tissue microarrays

pathol-Relational Database Structure to Manage High-Density Tissue Microarray Data and Images for Pathology Studies Focusing on Clinical Outcome

pathol-mol.array-Use of laser capture microdissection, cDNA microarrays, and tissue microarrays in advancing our understanding of prostate cancer

pathol-mol.array-Unlocking the archive-gene expression in paraffin-embedded tissue

pathol-mol.array-Towards a novel classification of human malignancies based on gene expression patterns

pathol-mol.array-Tissue microarray (TMA) technology-miniaturized pathology archives for high-throughput in situ studies

pathol-mol.array-The immune system and gene expression microarrays-new answers to old questions

pathol-mol.array-The Cancer Genome Anatomy Project-new resources for reading the molecular signatures of cancer

pathol-mol.array-Preface to Genomic Pathology-a New Frontier

pathol-mol.array-Gene profiling techniques and their application in angiogenesis and vascular development

pathol-mol.array-DNA methylation in genomic imprinting, development, and disease

pathol-mol.array-Analysing gene expression data from DNA microarrays to identify candidate genes

pathol-mol.array-An introduction to arrays

ns-psy-Microarray Expression Analysis

ns-Microarray Applications in Neuroscience

ns-DNA microarray gene expression analysis technology and its application to neurological disorders

microarrays-Statistical evaluation of differential expression on cDNA nylon arrays with replicated experiments

microarrays-Signal amplification by rolling circle amplification on DNA microarrays

microarrays-Robust and efficient synthetic method for forming DNA microarrays

microarrays-Manufacturing DNA microarrays of high spot homogeneity and reduced background signal

microarrays-DNA microarrays with stem–loop DNA probes-preparation and applications

microarrays-Detection of mitochondrial single nucleotide polymorphisms using a primer elongation reaction on oligonucleotide microarrays

microarrays-An evaluation of the performance of cDNA microarrays for detecting changes in global mRNA expression

microarray-Quantitative quality control in microarray image processing and data acquisition

microarray-Minimum information about a microarray experiment (MIAME)—toward standards for microarray data

microarray-Chemical nanoprinting-a novel method for fabricating DNA microchips

microarray-biotech-A new approach for filtering noise from high-density oligonucleotide microarray datasets

microarray-A high-throughput study of gene expression in preterm labor with a subtractive microarray approach

Microarray data analysis-a practical approach for selecting differentially expressed genes

biotech-Target gene identification from expression array data by promoter analysis

biotech-Suspension array technology-evolution of the flat-array paradigm

biotech-Single step generation of protein arrays from DNA by cell-free expression and in situ immobilisation (PISA method)

biotech-Negative selection-a method for obtaining low-abundance cDNAs using high-density cDNA clone arrays

biotech-Microarrays-handling the deluge of data and extracting reliable information

biotech-High-Throughput Array Analysis

biotech-Gene expression microarrays and the integration of biological knowledge

gt-Gene targeting in mosquito cells-a demonstration of 'knockout' technology in extrachromosomal gene arrays

biotech-DNA microarrays in medical practice

biotech-Diversity Arrays-a solid state technology for sequence information independent genotyping

Genomic-Automation for Genomics, Part Two-Sequencers, Microarrays, and Future Trends

genomes-Mining mouse microarray data

genome-microarray-Characterization of the expression ratio noise structure in high-density oligonucleotide arrays

genome-Functional Genomics, Gene Arrays, and the Future of Pathology

biotech-Basic microarray analysis-grouping and feature reduction

biochem-Transcriptomes, transcription activators and microarrays

cv-genetics-Microarray-Gene Expression in Failing Hearts Surveyed by High-Density Microarrays

cv-genetics-Microarrays in Determining Molecular Phenotype in Cardiac Growth, Development, and Response to Injury

cv-genetic-DNA microarray analysis of gene expression in endothelial cells in response to 24-h shear stress

bi-db-yMGV-helping biologists with yeast microarray data mining

cv-Current Reports-Hypertension-Hypertension and Metabolic Disarray-Diabetes Mellitus, Insulin Resistance and Obesity

bi-db-READ-RIKEN Expression Array Database

bi-db-HugeIndex-a database with visualization tools for high-density oligonucleotide array data from normal human tissues

bi-db-Gene Expression Omnibus-NCBI gene expression and hybridization array data repository

clin chem-Sequencing with Microarray Technology—A Powerful New Tool For Molecular Diagnostics

clin chem-Analysis Issues for Gene Expression Array Data

bi-Critical Assessment of Microarray Data Analysis-the 2001 challenge

cell-Analyzing high-density oligonucleotide gene expression array data

cell-Analysis of gene expression by microarrays-cell biologist's gold mine or minefield

ca-mol-Microarray and histopathological analysis of tumours-the future and the past

Mining mouse microarray data

bi-AMADA- analysis of microarray data

bi-A relational schema for both array-based and SAGE gene expresster release at nerve terminals

bi-A relational schema for both array-based and SAGE gene expression experiments

Construction of a Human Cardiovascular cDNA Microarray

bi-A Bayesian framework for the analysis of microarray expression data

bi-A Bayesian framework for the analysis of microarray expression data

Bootstrapping cluster analysis- Assessing the reliability of conclusions from microarray experiments

DNA microarrays in neuropsychopharmacology

bi-Processing and quality control of DNA array hybridization data

bi-DRAGON- Database Referencing of Array Genes Online

bi-A Bayesian framework for the analysis of microarray expression data

bi-A Bayesian framework for the analysis of microarray expression data

Detection of multiple proteins in an antibody-based protein microarray system

Analysis of complex brain disorders with gene expression microarrays

Analysis of complex brain disorders with gene expression microarrays

Image metrics in the statistical analysis of DNA microarray data

Transcriptomes, transcription activators and microarrays

DNA microarrays in neuropsychopharmacology

bi-Missing value estimation methods for DNA microarrays

proteome-Arrays for protein expression profiling

bi-Automated image analysis for array hybridization experiments

Array-based gene expression profiling to study aging

Tissue microarray technology for high-throughput molecular profiling of cancer

Antibody arrays for high-throughput screening of antibody-antigen interactions

Screening insertion libraries for mutations in many genes simultaneously using DNA microarrays

Far-Western based protein–protein interaction screening of high-density protein filter arrays

pharmacogenomics -Microchips, microarrays, biochips and nanochips- personal laboratories for the 21st century

mr-Microarray techniques in pathology

the Second International Meeting on Microarray Data Standards, Annotations, Ontologies and Databases

CREB:A stimulus induced transcription factor activated by adverse array of extracellular signals

DNA Arrays Reveal Cancer in Its Many Forms

Double-stranded DNA arrays next steps in the surface campaign

Cheap DNA arrays[#151]it's not all smoke and mirrors

Cheap DNA arrays it's not all smoke and mirrors

The integration of microarray information in the drug development process

Technology for microarray analysis of gene expression

array-T cell

microarray mutation

Gene Expression Studies Using Microarrays

Target gene identification from expression array data by promoter analysis

method-Protein and antibody arrays and their medical applications

method-Applications of nylon membrane arrays to gene expression analysis

method-Analysis of cellular adhesion by microarray expression profiling

Protein and antibody arrays and their medical applications

biotech-Discrete membrane arrays

proteome-Protein microarrays

proteome-Protein microarrays- prospects and problems

proteome-Proteins emerge from disarray

proteome-Protein arrays and microarrays

proteome-Microarrays and cell cycle transcription in yeast

proteome-Large-scale functional analysis using peptide or protein arrays

proteome-DNA microarrays for expression profiling

anay biotech-New developments in microarray technology

anay biotech-DNA microarrays- raising the profile

anay biotech-Applications of peptide arrays prepared by the SPOT-technology

Microarray techniques in pathology

method-Validation of Array-Based Gene Expression Profiles by Real-Time (Kinetic) RT-PCR

genome-n-Experimental annotation of the human genome using microarray technology

ca-Microarrays under the microscope

bi-The Stanford Microarray Database

genome-Target gene identification from expression array data by promoter analysis

Comparing functional genomic -lessons microarray analyses of host–pathogen interactions

nano-Biotechnological applications of lab-chips and microarrays

nano-Atomic force microscopy of parallel DNA branched junction arrays

Model-based analysis of oligonucleotide arrays

Expressing what's on your mind- DNA arrays and the brain

proteome-Profiling Changes in Gene Expression during Differentiation and Maturation of Monocyte-derived Dendritic Cells Using Both Oligonucleotide Microarrays and Proteomics

Monitoring expression of genes involved in drug metabolism and toxicology using DNA microarrays

Microarray analysis of nicotine-induced changes in gene expression in endothelial cells

method-Gene Array Analysis of Osteoblast Differentiation

Comparison of the efficacy of a subcutaneous array electrode with a subcutaneous patch electrode, a prospective randomized study

Gene Expression Profiling of Human Stent-Induced Neointima by cDNA Array Analysis of Microscopic Specimens Retrieved by Helix Cutter Atherectomy

 


更新于2002-10-16