Cardiovascular Bioactive Peptide



心血管活性多肽
近年来，基因组、蛋白质组计划的实施极大的推动了调节肽的研究，调节肽在人体生命活动中的重要性使人们逐渐从对基因、蛋白等生物大分子的研究过渡到对小分子多肽的研究，尤其是心血管活性多肽的研究，它在心血管生理和病理生理活动的调节和信号转导中发挥着不可替代的作用，去年我们曾经做过调节肽的特别报道，今年我们又收集了最新发表的心血管活性多肽的报道和文献300篇并作了较系统的分类，这其中一些是老肽新功能，一些是新发现的活性多肽，奉献给大家，更多的文献请查阅cmbi的综述查询和相关栏目：
ANP-BNP-CNP Adm-CGRP Angiotensin Endothelin Urocortin Ghrelin Caveolins Cardiotrophin Nephrin Calcineurin Calpain Apelin Galanin 其它活性多肽	ANP-BNP-CNP cv-anp-Atrial natriuretic peptide in atrial fibrillation cv-anp-Atrial natriuretic factor inhibits mitogen-induced growth in aortic smooth muscle cells cv-anp-A-type natriuretic peptide receptor in the spontaneously hypertensive rat cv-anp-Atrial natriuretic peptide level after cardioversion of chronic atrial fibrillation cv-anp-Biochemistry and physiology of the natriuretic peptide receptor guanylyl cyclases cv-anp-B-Type Natriuretic Peptide — A Window to the Heart cv-anp-B-type natriuretic peptide after percutaneous transluminal septal myocardial ablation cv-anp-Divergent effects of ANP and BNP in acute heart failure cv-anp-Evaluation of the atrial natriuretic peptide gene in stroke cv-anp-Impact of age and sex on plasma natriuretic peptide levels in healthy adults cv-anp-Increased plasma brain natriuretic peptide level as a guide for silent myocardial ischemia in patients with non-obstructive hypertrophic cardiomyopathy cv-anp-Molecular cloning and functional characterization of the upstream rat atrial natriuretic peptide promoter cv-anp-Natriuretic peptides in the diagnosis of heart disease-First amongst equals cv-anp-N-terminal pro brain natriuretic peptide on admission for early risk stratification of patients with chest pain and no ST-segment elevation cv-anp-Plasma atrial natriuretic peptide concentration inversely correlates with left atrial collagen volume fraction in patients with atrial fibrillation cv-anp-Plasma ProANP1–30 Reflects Salt Sensitivity in Subjects With Heredity for Hypertension cv-anp-Prognostic value of N-terminal pro-atrial and pro-brain natriuretic peptide in patients with acute coronary syndromes cv-anp-Rapid Measurement of B-Type Natriuretic Peptide in the Emergency Diagnosis of Heart Failure cv-anp-The atrial natriuretic peptide-a changing view cv-anp-Usefulness of plasma N-terminal proatrial natriuretic peptide (proANP) as an early predictor of outcome in unstable angina pectoris or non-ST-elevation acute myocardial infarction cv-anp-Utility of a BNP as a marker for RV dysfunction in acute pulmonary embolism back ADM-CGRP cv-adm-ADM-myocardial function-energy metabolism cv-adm-Adrenomedullin and PAMP-discovery, structures, and cardiovascular functions cv-adm-Adrenomedullin and proadrenomedullin N-terminal 20 peptide in the normal prostate and in prostate carcinoma cv-adm-Adrenomedullin and the integrative physiology of fluid and electrolyte balance cv-adm-Adrenomedullin and the microvasculature cv-adm-Adrenomedullin as a pancreatic hormone cv-adm-Adrenomedullin binding protein-1 modulates vascular responsiveness to adrenomedullin cv-adm-Adrenomedullin functions as an important tumor survival factor in human carcinogenesis cv-adm-Adrenomedullin in mammalian embryogenesis cv-adm-Adrenomedullin in the adrenal cv-adm-Adrenomedullin in the central nervous system cv-adm-Adrenomedullin, an Endogenous Peptide, Counteracts Cardiovascular Damage cv-adm-Adrenomedullin-An Autocrine-Paracrine Factor for Cardiorenal Protection cv-adm-Adrenomedullin-receptor and signal transduction cv-adm-Aldosterone augments adrenomedullin production without stimulating N-terminal 20 peptide secretion i cv-adm-Aldosterone augments adrenomedullin production without stimulating pro N-terminal 20 peptide secretion cv-adm-Aldosterone-adrenomedullin-a new feedback regulation in blood vessels cv-adm-Aldosterone–adrenomedullin-a new feedback regulation in blood vessels cv-adm-Biology of adrenomedullin cv-adm-Cerebral endotheli cells are a major source of adrenomedullin cv-adm-Cerebral endothelial cells are a major source of adrenomedullin cv-adm-Comparison of the expression of calcitonin receptor-like receptor (CRLR) and receptor activity modifying proteins (RAMPs) with CGRP and adrenomedullin binding in cell lines cv-adm-Effects of different peptide fragments derived from proadrenomedullin on gene expression of adrenomedullin gene cv-adm-Functional interaction of G protein-coupled receptors of the adrenomedullin peptide family with accessory receptor-activity-modifying proteins cv-adm-Gene expression of adrenomedullin in failing myocardium cv-adm-Identification and actions of factor H as an adrenomedullin binding protein cv-ADM-Immunohistochemical of Calcitonin Receptor–Like Receptor and Receptor Activity–Modifying Proteins cv-adm-Inflammatory Cytokines Stimulate Adrenomedullin Expression Through Nitric Oxide–Dependent and –Independent Pathways cv-adm-Large-scale production of functional human adrenomedullin-expression, cleavage, amidation, and purification cv-adm-Long-Term Adrenomedullin Infusion Improves Survival in Malignant Hypertensive cv-adm-Molecular forms of adrenomedullin in pericardial fluid and plasma in patients with ischaemic heart disease cv-adm-Multiple roles of adrenomedullin revealed by animal models cv-adm-Neutralization of Adrenomedullin Inhibits the Growth of Human Glioblastoma Cell Lines in Vitro and Suppresses Tumor Xenograft Growth in Vivo cv-adm-Novel actions of proadrenomedullin N-terminal 20 peptide cv-adm-Rat RAMP domains involved in adrenomedullin binding specificity cv-adm-Regulation of adrenomedullin expression and release cv-adm-Renoprotective Effect of Chronic Adrenomedullin Infusion in Dahl Salt-Sensitive Rats cv-adm-Renoprotective Effect of Chronic Adrenomedullin Infusion cv-adm-Resistance to Neointimal Hyperplasia and Fatty Streak Formation in Mice With Adrenomedullin Overexpression cv-adm-Ribozyme compromise of adrenomedullin mRNA reveals a physiological role in the regulation of water intake cv-adm-Role of Endogenous Adrenomedullin in the Regulation of Vascular Tone and Ischemic Renal Injury cv-adm-structuration and cardiovascular function cv-adm-The Effects of Adrenomedullin Overexpression in Breast Tumor Cells cv-adm-The Mammalian Calcitonin Gene-Related Peptides, Adrenomedullin, Amylin, and Calcitonin Receptors cv-peptide-cgrp-Characterization of calcitonin gene-related peptide (CGRP) receptors and their receptor-activity-modifying proteins (RAMPs) in human brain microvascular cv-peptide-cgrp-Effect of the CGRP receptor antagonist BIBN4096BS in human cerebral, coronary and omental arteries cv-peptide-cgrp-Efficacy of the non-peptide CGRP receptor antagonist BIBN4096BS in blocking CGRP-induced dilations in human and bovine cerebral arteries cv-peptide-cgrp-Regulation and function of the CGRP receptor complex in human granulopoiesis cv-peptide-cgrp-Role of calcitonin gene-related peptide (CGRP) in chronic hypoxia-induced pulmonary hypertension cv-peptide-cgrp-The molecular pharmacology of CGRP and related peptide receptor subtypes back Angiotensin cv-agt- cv-agt-Role of AT2 Receptors in the Cardioprotective Effect of AT1 Antagonists cv-agt- AT1 Receptor Antagonists Inhibit Platelet Adhesion and Aggregation by Nitric Oxide cv-agt-Angiotensin 1-9 and 1-7 Release in Human Heart- Role of Cathepsin A cv-agt-AT2 Receptor-Mediated Relaxation Is Preserved After Long-Term AT1 Receptor Blockade cv-agt-Role of p47phox in Vascular Oxidative Stress and Hypertension Caused by Angiotensin II cv-agt-Aldosterone Breakthrough During Angiotensin II Receptor Antagonist Therapy in Stroke cv-agt-Angiotensin 1-9 and 1-7 Release in Human Heart-Role of Cathepsin A cv-agt-Angiotensin I, angiotensin II and their biologically active peptides cv-agt-Angiotensin II and trials of cardiovascular outcomes cv-agt-Angiotensin II induced inflammation in the kidney and in the heart of double transgenic rats cv-agt-Angiotensin II Induces Tumor Necrosis Factor Biosynthesis in the Adult Mammalian Heart Through a Protein Kinase C–Dependent Pathway cv-agt-Angiotensin II stimulates synthesis of vascular smooth muscle cell proteoglycans cv-agt-Angiotensin II Type 1 Receptor Antagonism Improves Hypercholesterolemia-Associated Endothelial Dysfunction cv-agt-Angiotensin IV Is a Potent Agonist for Constitutive Active Human AT1 Receptors cv-agt-Antiangiogenic Effect of Angiotensin II Type 2 Receptor in Ischemia-Induced Angiogenesis cv-agt-Biological properties of the angiotensin peptides other than angiotensin II cv-agt-Comparison of ACE, neutral endopeptidase (NEP) and dual ACE-NEP inhibition on blood pressure cv-agt-Differential Regulation of Elevated Renal Angiotensin II in Chronic Renal Ischemia cv-agt-From the hope to the ontarget and the transcend studies-challenges in improving prognosis cv-agt-Hormonal regulation of the human adipose-tissue renin–angiotensin system cv-agt-Neutral endopeptidase inhibition cv-agt-Overexpression of the renin-angiotensin system in human visceral adipose tissue cv-agt-Role of Angiotensin II–Regulated Apoptosis Through Distinct AT1 and AT2 Receptors in Neointimal Formation cv-agt-Role of central angiotensin II receptors in cold-induced hypertension, cv-agt-Role of neutral endopeptidase and angiotensin-converting enzyme in t hypertension cv-agt-The role of the renin-angiotensin system in the development of cardiovascular disease cv-agt-Tissue activity of circulating prorenin, cv-agt-Tissue activity of circulating prorenin cv-agt-Tissue renin-angiotensin system and end-organ damage cv-agt-Vascular Inflammation and the Renin-Angiotensin System back Endothelin cv-as-Crosstalk of endothelin-1 and platelet-derived growth factor in cardiac allograft arteriosclerosis cv-et- Vascular Remodeling After Injury Revealed by Endothelin-B Receptor-Knockout Mice cv-et-A role for endothelin receptor blockade in improving the endothelial function of coronary artery grafts cv-et-Activated Mast Cells Increase the Level of Endothelin-1 mRNA in Cocultured Endothelial Cells cv-et-Activation of the cardiac endothelin system in left ventricular hypertrophy cv-et-advances in endothelin research and first antagonist gains FDA approval cv-et-Autocrine Stimulation of Cardiac Na+-Ca2+ Exchanger Currents by Endogenous Endothelin cv-et-bioactive peptide endothelin causes multiple biologic responses cv-et-Biphenylsulfonamide Endothelin Receptor Antagonists cv-et-Bosentan, a dual endothelin receptor antagonist cv-et-Chronic endothelin receptor blockade prevents renal vasoconstriction and sodium retention cv-et-Chronic ETA receptor blockade prevents endothelial dysfunction of small arteries cv-et-Collagen accumulation after myocardial infarction- effects of ETA receptor blockade and implications for early remodeling cv-et-Combined Endothelin Receptor Blockade Evokes Enhanced Vasodilatation in Patients With Atherosclerosis cv-et-Complete results of the first randomized, placebo-controlled study of bosentan, a dual endothelin receptor antagonist, in pulmonary arterial hypertension cv-et-Cortical expression of endothelin receptor subtypes A and B following middle cerebral artery occlusion cv-et-Effect of Ro 61-1790, a selective endothelin-A receptor antagonist cv-et-Effects of cerebrovascular challenges on plasma endothelin cv-et-Endothelial cell dynamics and complexity theory cv-et-Endothelial responses to mechanical stress cv-et-Endothelin Antagonism and Interleukin-6 Inhibition Attenuate Effects of C-Reactive Protein cv-et-Endothelin A-receptor antagonist administration immediately after experimental myocardial infarction cv-et-Endothelin Blockade on Basal and Stimulated Forearm Blood Flow in Patients With Essential Hypertension cv-et-Endothelin in the mechanism of endothelial injury and neutrophil adhesion in the post-ischemic guinea-pig heart cv-et-Endothelin is an important determinant of renal function cv-et-Endothelin Mediates Increased Pulmonary Vascular Tone in Patients With Heart Failure cv-et-Endothelin receptors cv-et-Endothelin suppresses cell migration via the JNK signaling pathway cv-et-Endothelin-1-Induced Enhancement of Coronary Smooth Muscle Contraction via MAPK-Dependent cv-et-Endothelium-derived mediators and hypoxic pulmonary vasoconstriction cv-et-Enhanced vasoconstrictor effect of big endothelin-1 in patients with atherosclerosis cv-et-Function and Regulation of Endothelin-1 and Its Receptors in Salt Sensitive Hypertension cv-et-Function of the endothelinB receptor in cardiovascular physiology and pathophysiology cv-et-Hydrogen peroxide regulation of bovine endothelin-converting enzyme-1 cv-et-Increased Activity of Endogenous Endothelin in Patients With Type II Diabetes Mellitus cv-et-Leptin Induces Endothelin-1 in Endothelial Cells cv-et-Peptides acting at gap junctions cv-et-Pharmacological possibilities for protection against myocardial reperfusion injury cv-et-Plasma endothelin in patients with acute aortic disease cv-et-Preproendothelin-1 Gene Polymorphism Is Related to a Change in Vascular Reactivity cv-et-Renal protective effect of YM598, a selective endothelin ETA receptor antagonist cv-et-Role of endothelin ETB receptors in the renal hemodynamic and excretory responses to big endothelin-1 cv-et-Role of endothelin-1 in a cirrhotic rat model with endotoxin induced acute renal failure cv-et-Selective Upregulation of Endothelin B Receptor Gene Expression in Severe Pulmonary Hypertension cv-et-Association Between Plasma Endothelin-1 Levels and Cheyne-Stokes Respiration in Patients With Congestive Heart Failure cv-et-Clinical Efficacy of Sitaxsentan, an Endothelin-A Receptor Antagonist cv-et-Diabetes-Induced Renal Overexpression of Endothelin-1 and Endothelin A and B Receptors cv-et-Endothelin 1 Type A Receptor Antagonism Prevents Vascular Dysfunction cv-cardiotrophin-Cardiotrophin-1 stimulates endothelin-1 via gp130 in vascular endothelial cells cv-drug-Darusentan-An effective endothelinA receptor antagonist for treatment of hypertension cv-hp-Cardiac and vascular fibrosis and hypertrophy in aldosterone-infused rats-role of endothelin- cv-hp-Darusentan-An effective endothelinA receptor antagonist for treatment of hypertension cv-hp-Darusentan0An effective endothelinA receptor antagonist for treatment of hypertension cv-hp-Role of nitric oxide, endothelin-1, and inflammatory cytokines in blood pressure regulation cv-inf-Proinflammatory effects of angiotensin II and endothelin cv-peptide-Endothelin, nephropathy, and blood pressure cv-peptide-Endothelin, nephropathy, and blood pressure cv-peptide-Endothelin-1-a useful marker for asthmatic inflammation cv-peptide-Endothelin-1 Induces Vascular Endothelial Growth Factor by Increasing Hypoxia-inducible Factor-1 cv-peptide-Two Novel Transcripts for Human Endothelin B Receptor Produced by RNA Editing-Alternative Splicing from a Single Gene cv-risk-Mental Stress Induces Prolonged Endothelial Dysfunction via Endothelin-A Receptors cv-therapy-Long-Term Endothelin A Receptor Blockade Inhibits Electrical Remodeling in Cardiomyopathic mol med-cv-Renal damage and salt-dependent hypertension in aged transgenic mice overexpressing endothelin-1 pharmacol-Update on Endothelin Receptor Nomenclature reproduction-nter-relationships between endothelin and prostaglandin F2 in corpus luteum function respir-Role of endothelin-1 in lung disease cv-peptide-Endothelin-2 is a macrophage chemoattractant cv-peptide-Mechanism of endothelin-1-induced cytosolic Ca2+ mobility in cultured H9c2 myocardiac ventricular cells cv-peptide-Proceedings of the Seventh International Conference on Endothelin (ET-7) cv-phramacol-Endothelin 1-Induced Pressor Response and Vasopressin Release in Rats with Heart Failure cv-phramacol-Endothelin A Receptor Blockade Decreases Expression of Growth Factors and Collagen and Improves Matrix Metalloproteinase-2 Activity in Kidneys from Stroke-Prone Spontaneously Hypertensive Rats cv-phramacol-Endothelin B Receptor-Mediated Regulation of Endothelin-1 Content and Release in Cultured Porcine Aorta Endothelial Cell cv-phramacol-Endothelin-Induced Myoplasmic Ca2+ Responses and Tyrosine Phosphorylation in Coronary Smooth Muscle cv-phramacol-Entry-Into-Humans Study with Tezosentan, an Intravenous Dual Endothelin Receptor Antagonist therapy-Bosentan-a dual endothelin receptor antagonist therapy-Endothelin receptor antagonists in cardiology clinical trials back Urocortin cv-Urocortin-Activation of Protein Kinase B-Akt by Urocortin is Essential to Protect Cardiac Cells cv-peptide-urotensin-Corticotropin Releasing Hormone Receptor mRNA Levels are Regulated by Testosterone cv-peptide-Urotensin-The Role of Urotensin II Gene in the Genetic Susceptibility to the Type 2 Diabetes in Chinese Population cv-peptide-Urocortin-KATP Channel Gene Expression Is Induced by Urocortin and cv-peptide-urotensin-Cardiovascular effects of urotensin II cv-peptide-urotensin-Human Urotensin II-Induced Contraction and VSMC Proliferation Are Mediated by RhoA and Rho-Kinase cv-peptide-urotensin-Synergistic Effect of Urotensin II With Mildly Oxidized LDL on DNA Synthesis in VSMC cv-Urocortin-Down-regulation of corticotropin-releasing hormone receptor type 2beta mRNA expression in the rat cardiovascular system cv-Urocortin-Expression of Urocortin and Corticotropin-Releasing Factor Receptor Subtypes in the Human Heart cv-Urocortin-Human urocortin II, a new CRF-related peptide cv-Urocortin-Identification of urocortin mRNA and peptide in the human endometrium cv-Urocortin-induced endothelium-dependent relaxation of rat coronary artery cv-Urocortin-KATP Channel Gene Expression Is Induced by Urocortin and Mediates Its Cardioprotective Effect cv-Urocortin-KATP Channel Gene Expression Is Induced by Urocortin and Mediates Its Cardioprotective EffectCardiotrophin-1 and urocortin cause protection by the same pathway and hypertrophy cv-Urocortin-Mutation Screening of the Urocortin Gene-Identification of New Single Nucleotide Polymorphisms and Association Studies with Obesity cv-Urocortin-Relaxation by urocortin of human saphenous veins cv-Urocortin-The corticotropin-releasing factor family of peptides and CRF receptors cv-Urocortin-The CRF peptide family and their receptors cv-Urocortin-The CRF peptide family and their receptors- cv-Urocortin-Urocortin has cell-proliferative effects on cardiac non-myocytes cv-Urocortin-Urocortin promotes hemodynamic and bioenergetic recovery and improves cell survival in the isolated rat heart exposed to ischemia cv-Urocortin-Urocortin protects the heart from reperfusion injury back Ghrelin cv-Ghrelin an orexigenic and somatotrophic signal from the stomach an orexigenic and somatotrophic signal from the stomach-discovery of the natural endogenous ligand for the growth hormone secretagogue receptor cv-Ghrelin-Central ghrelin production does not substantially contribute to systemic ghrelin concentrations cv-Ghrelin-Chicken Ghrelin-Purification, cDNA Cloning, and Biological Activity cv-Ghrelin-Circulating ghrelin levels in basal conditions and during glucose tolerance test cv-Ghrelin-Delayed Short-Term Secretory Regulation of Ghrelin in Obese Animals-Evidenced by a Specific RIA for the Active Form of Ghrelin cv-Ghrelin-Elevated Circulating Level of Ghrelin in Cachexia Associated With Chronic Heart Failure cv-Ghrelin-Expression and action of the growth hormone releasing peptide ghrelin and its receptor in prostate cancer cell lines cv-Ghrelin-Ghrelin stimulates insulin secretion from the pancreas cv-Ghrelin-Ghrelin, A Novel Placental-Derived Hormone cv-Ghrelin-Ghrelin, growth and obesity cv-Ghrelin-Ghrelin-an orexigenic and somatotrophic signal from the stomach cv-Ghrelin-G-protein-coupled receptors in human atherosclerosis-urotensin-II, apelin and ghrelin receptors cv-Ghrelin-Hormonal regulation of the human ghrelin receptor gene transcription cv-Ghrelin-Neuroendocrine and peripheral activities of ghrelin cv-Ghrelin-not just another stomach hormone cv-Ghrelin-Role for central ghrelin in food intake and secretion cv-Ghrelin-Role of Ghrelin in the Regulation of Vasopressin Release cv-Ghrelin-Structure-activity relationship of ghrelin cv-Ghrelin-vasodilatory effect of ghrelin back Caveolins cv-Caveolae and caveolin in immune cells cv-caveolae-Structure and function of endothelial caveolae cv-Caveolins and Caveola-Molecular and Functional Relationships cv-Caveolins and Caveola-Cardiac myocyte adenosine receptors and caveolae cv-Caveolins and Caveola-Caveolae and caveolin isoforms in rat peritoneal macrophages cv-Caveolins and Caveola-Caveolae and caveolin-3 in muscular dystrophy cv-Caveolins and Caveola-Caveolae and intracellular trafficking of cholesterol cv-Caveolins and Caveola-Caveolae and the caveolins in human disease cv-Caveolins and Caveola-Caveolin-1, a putative tumour suppressor gene cv-Caveolins and Caveola-Cell biology of caveolae and caveolin cv-Caveolins and Caveola-Influence of caveolin, cholesterol, and lipoproteins on nitric oxide synthase cv-Caveolins and Caveola-Relationships between caveolae and eNOS cv-Caveolins and Caveola-Rnvolvement of caveolae and caveolae-like domains in signalling, cell survival and angiogenesis cv-Caveolins and Caveola-The Vesiculo–Vacuolar Organelle (VVO)-A New Endothelial Cell Permeability Organelle back Cardiotrophin cv-cardiotrophin-Augmented Expression of Cardiotrophin-1 in Failing Human Hearts cv-peptide-Cardiotrophin-1 in Heart Failure cv-peptide-Cardiotrophin-1 Stimulation of Cardiac Fibroblast Growth cv-cardiotrophin-Cardiotrophin-1 (CT-1) can protect the adult heart from injury when added both prior to ischaemia and at reperfusion cv-cardiotrophin-Cardiotrophin-1 and urocortin cause protection by the same pathway and hypertrophy via cv-cardiotrophin-Cardiotrophin-1 can protect cardiac myocytes from injury cv-cardiotrophin-Cardiotrophin-1 stimulates endothelin-1 via gp130 in vascular endothelial cells cv-cardiotrophin-Cardiotrophin-1 Stimulation of Cardiac Fibroblast Growth cv-cardiotrophin-Cardiotrophin-1, a Muscle-Derived Cytokine, Is Required for the Survival of Subpopulations of Developing Motoneurons cv-cardiotrophin-Cardiotrophin-Like Cytokine on B Cell Function cv-cardiotrophin-CT-1 mediated cardioprotection against ischaemic re-oxygenation injury is mediated by PI3 kinase, Akt and MEK1 cv-cardiotrophin-functional responses to cardiotrophin-like cytokine cv-cardiotrophin-Heat shock protein-56 is induced by cardiotrophin-1 and mediates its hypertrophic effect cv-cardiotrophin-immunochemiluminometric assay for cardiotrophin-1 detects elevated plasma levels in human heart failure cv-cardiotrophin-In vivo electrotransfer of the cardiotrophin-1 gene into skeletal muscle cv-cardiotrophin-Increased expression of cardiotrophin-1 during ventricular remodeling cv-cardiotrophin-Plasma cardiotrophin-1 following acute myocardial infarction cv-cardiotrophin-Protective effects of cardiotrophin-1 adenoviral gene transfer on neuromuscular degeneration cv-cardiotrophin-Relationship between plasma level of cardiotrophin-1 and left ventricular mass index in patients with dilated cardiomyopathy cv-cardiotrophin-Resistance in Cardiovascular System in Rat Treated With Cardiotrophin-1 In Vivo cv-cardiotrophin-Signaling Pathways Recruited by the Cardiotrophin-like Cytokine-Cytokine-like Factor-1 Composite Cytokine cv-cardiotrophin-The Cytoprotective Effects of the Glycoprotein 130 Receptor-coupled Cytokine, Cardiotrophin-1, Require Activation of NF-B cv-cardiotrophin-Cardiotrophin-1 and urocortin cause protection by the same pathway and hypertrophy via distinct pathways in cardiac myocytes back Nephrin cv-peptide-Modulation of nephrin in the diabetic kidney cv-peptide-nephrin-Cloning of rat nephrin cv-peptide-nephrin-Molecular cloning, expression, and distribution of glomerular epithelial protein cv-peptide-nephrin-Novel mutation in the nephrin gene of a Japanese patient with congenital nephrotic syndrome cv-peptide-nephrin-Podocin, a raft-associated component interacts with CD2AP and nephrin cv-peptide-Nephrin in experimental glomerular disease cv-peptide-nephrin-Alternatively Spliced Nephrin in Experimental Glomerular Disease of the Rat cv-peptide-nephrin-Patterns of nephrin and a new proteinuria-associated protein expression back Calcineurin cv-Calcineurin and cardiac hypertrophy cv-peptide-calcineurin-Calcineurin and hypertrophic heart disease- novel insights and remaining questions cv-peptide-calcineurin-Calcineurin inhibitors and cardiac hypertrophy cv-peptide-calcineurin-Crystal structure of human calcineurin complexed cv-peptide-calcineurin-Enhanced myocyte contractility and Ca2+ handling in a calcineurin transgenic model of heart failure cv-peptide-calcineurin-Identification of two calcineurin B-binding proteins cv-peptide-calcineurin-Mechanism of action of the calcineurin inhibitors cv-peptide-calcineurin-Nephrotoxicity of calcineurin inhibitors cv-peptide-calcineurin-Old and new tools to dissect calcineurin’s role in pressure-overload cardiac hypertrophy cv-Calcineurin and hypertrophic heart disease cv-Calcineurin-ATP-binding cassette transporters and calcineurin inhibitors-potential clinical implications cv-Calcineurin-Calcineurin and cardiac hypertrophy-2 cv-Calcineurin-Calcium, Calcineurin, and the Control of Transcription cv-Calcineurin-Cyclic AMP signalling cv-Calcineurin-CYTOPLASMIC SIGNALING PATHWAYS THAT REGULATE CARDIAC HYPERTROPHY cv-Calcineurin-The dephosphins-dephosphorylation by calcineurin triggers synaptic vesicle endocytosis cv-Calcineurin-p38 Mitogen-activated Protein Kinase-, Calcium-Calmodulin-dependent Protein Kinase and Calcineurin-mediated Signaling Pathways Transcriptionally Regulate Myogenin Expression cv-Calcineurin as a multifunctional regulator cv-Calcineurin as a multifunctional regulator-fig- cv-Calcineurin as a multifunctional regulator-fig2 cv-Calcineurin as a multifunctional regulator-fig3 cv-Calcineurin as a multifunctional regulator-fig4 cv-Calcineurin as a multifunctional regulator-fig5 cv-Calcineurin as a multifunctional regulator-fig6 cv-Calcineurin-Molecular and Cellular Mechanisms of Cardiotoxicity back Calpain cv-Calpain and Mitochondria in Ischemia-Reperfusion Injury cv-peptide-Calpain as an effector of the Gq signaling pathway for inhibition of Wnt--catenin-regulated cell proliferation cv-Calpain Function in the Modulation of Signal Transduction Molecules cv-calpain proteases in cell motility cv-Calpain cv-Calpain-calpain proteases in cell motility cv-Calpain-The calpain family and human disease cv-Calpain-The Structure of Calcium-Free Human m-Calpain-Implications for Calcium Activation and Function cv-Calpain-The structure of calpain cv-Calpain-The Structure of Calpain- cv-Calpain-The structure of calpain-fig1 cv-Calpain-The structure of calpain-fig2 cv-Calpain-The structure of calpain-fig3 cv-Calpain-The structure of calpain-fig4 back Apelin cv-peptide-alpelin-Novel neurotransmitters as natural ligands of orphan G-protein-coupled receptors cv-peptide-apelin is upregulated during formation of the retinal vessels cv-peptide-Apelin peptides block the entry of human immunodeficiency virus cv-peptide-Apelin, the natural ligand of the orphan receptor APJ cv-peptide-Apelin, the Novel Endogenous Ligand of the Orphan Receptor APJ, Regulates Cardiac Contractility cv-peptide-Apelin, the Novel Endogenous Ligand of the Orphan Receptor APJ cv-peptide-apelin-Distribution of apelin-synthesizing neurons in the adult rat brain cv-peptide-apelin-Distribution of mRNA encoding the rat homologue of th apelin in brain and peripheral tissues cv-peptide-apelin-Molecular properties of apelin cv-peptide-apelin-The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism back Galanin cv-peptide-galanin-Anticonvulsant activity of a nonpeptide galanin receptor agonist cv-peptide-galanin-Can galanin also be considered as growth-associated protein 3.2 cv-peptide-galanin-Characterisation of a new chimeric ligand for galanin receptors- galanin(1–13)-[d-Trp32]-neuropeptide Y(25–36)amide cv-peptide-galanin-determination of acetylcholine, serotonin and noradrenaline release in galanin transgenic mice cv-peptide-galanin-Distribution of galanin messenger RNA-expressing cells in murine brain and their regulation by leptin in regions of the hypothalamus cv-peptide-galanin-Effects of galanin on the secretion and proliferative activity of the immature and regenerating adrenal glands cv-peptide-galanin-Galanin Is a Potent In Vivo Modulator of Mesencephalic Serotonergic Neurotransmission cv-peptide-galanin-Galanin modulates the activity of proopiomelanocortin neurons cv-peptide-galanin-Galanin receptor over-expression within the amygdala in early Alzheimer's disease cv-peptide-galanin-Galanin receptor subtypes cv-peptide-galanin-Modulatory Effects of Galanin in the Lateral Bed Nucleus of the Stria Terminalis cv-peptide-galanin-Nerve injury induces plasticity that results in spinal inhibitory effects of galanin cv-peptide-galanin-Pharmacological evidence supporting a role for galanin in cognition and affect cv-peptide-galanin-Processing of neuropeptide Y, galanin, and somatostatin in the cerebrospinal fluid of patients with Alzheimer’s disease cv-peptide-galanin-Stimulation Effect of Galanin-Like Peptide (GALP) on Luteinizing Hormone-Releasing Hormone cv-peptide-galanin-Suppressed kindling epileptogenesis in mice with ectopic overexpression of galanin cv-peptide-galanin-tachycardia induced by galanin (1–15) but not by galanin (1–29) cv-peptide-galanin-The effects of galanin on long-term synaptic plasticity cv-peptide-galanin-The neuropeptide galanin- A modulator of 5-HT1A receptor mechanisms cv-peptide-galanin-The role of galanin as a multi-functional neuropeptide in the nervous system cv-peptide-galanin-Triple therapy with octreotide, galanin and serotonin induces necrosis and increases apoptosis of a rat colon carcinoma 其它活性多肽 cv-Calmodulin modulation of proteins involved in excitation-contraction coupling cv-peptide-add-ADD1 460W Allele Associated With Cardiovascular Disease in Hypertensive Individuals cv-peptide-add-Alpha adducin 1 Gly460Trp polymorphism affects the rate of fibrosis development cv-peptide-add-alpha]-Adducin 460Trp Allele Is Associated With Erythrocyte Na Transport Rate cv-peptide-add-alpha]-Adducin and Angiotensin I-Converting Enzyme Polymorphisms in Essential Hypertension cv-peptide-add-Association of protein kinase Cλ with adducin in 3T3-L1 adipocytes cv-peptide-add-Diuretic Therapy, the [alpha]-Adducin Gene Variant, and the Risk of Myocardial Infarction or Stroke cv-peptide-add-Hypertension in [beta]-Adducin cv-peptide-add-Hypertension-Linked Decrease in the Expression of Brain [gamma]-Adducin cv-peptide-add-Low-Renin Hypertension, Altered Sodium Homeostasis, and an [alpha]-Adducin Polymorphism cv-peptide-add-Role of the [alpha]-adducin genotype on renal disease progression cv-peptide-Adipocyte Fatty Acid-Binding Protein, aP2, Alters Late Atherosclerotic Lesion Formation cv-peptide-Antiproliferative action of valorphin in cell cultures cv-peptide-Mechanisms regulating the expression, self-maintenance, and signaling-function of the bradykinin B2 and B1 receptors cv-Peptides in apoptosis research cv-peptide-Solution structure of nociceptin peptides cv-peptide-Structural, kinetic and cytotoxicity aspects of 12-28 -amyloid protein fragment cv-peptide-add-Adducin Polymorphisms and Risk of Subclinical and Clinical Stroke cv-peptide-add-an Alpha-Adducin Polymorphism (460TRP) Is Associated with Salt-Sensitivity and Low-Renin Hypertension in Humans cv-peptide-add-Genetic mechanisms underlying the regulation of urinary sodium excretion and arterial blood pressure- the role of adducin cv-peptide-add-Lack of Association of 3 Functional Gene Variants With Hypertension in African Americans cv-peptide-The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation cv-peptide-Augmented Expression of Cardiotrophin-1 in Failing Human Hearts cv-peptide-Cyclophilins cv-peptide-Endophilin-1- a multifunctional protein cv-peptide-Molecular pharmacology and structure of VPAC Receptors for VIP and PACAP cv-peptide-Neuropeptide AF and FF Modulation of Adipocyte Metabolism. PRIMARY INSIGHTS FROM FUNCTIONAL GENOMICS AND EFFECTS ON -ADRENERGIC RESPONSIVENESS cv-peptide-Neurotrophin channels excitement cv-peptide-Neurotrophin-evoked depolarization requires the sodium channel NaV1.9 cv-peptide-NN2211- a long-acting glucagon-like peptide-1 derivative with anti-diabetic effects cv-peptide-Peptides acting at gap junctions cv-peptide-Proteinuria and prenatal diagnosis of congenital nephrosis in fetal carriers of nephrin gene mutations cv-peptide-Relaxin peptides are new global players cv-peptide-Shedding of Kidney Injury Molecule-1, a Putative Adhesion Protein Involved in Renal Regeneration cv-peptide-Somatostatin inhibits glucagon-like peptide-1-induced insulin secretion cv-peptide-The antiangiogenic activity of cleaved high molecular weight kininogen is mediated through binding to endothelial cell tropomyosin cv-peptide-Vasoactive intestinal peptide (VIP) inhibits the proliferation of bone marrow progenitors peptide-Identification and Properties of Anti-chaperone-like Peptides peptide-Inhibition of Amyloid Fiber Assembly by Both BiP and Its Target Peptide peptide-Molecular cloning and functional expression of the first insect FMRFamide receptor peptide-Role of the C-terminal propeptide in the activity and maturation of -interferon-inducible lysosomal thiol reductase peptide-Soluble peptide-MHC monomers cause activation of CD8+ T cells through transfer of the peptide to T cell MHC molecules cv-pepide-CD36 Mediates the Cardiovascular Action of Growth Hormone-Releasing Peptides in the Heart cv-peptide-A peptide derived from human prothrombin fragment 2 inhibits prothrombinase and angiogenesis cv-peptide-Angiostatin Inhibits Coronary Angiogenesis During Impaired Production of Nitric Oxide cv-peptide-Cardiovascular Disease and Insulin-Like Growth Factor I cv-peptide-Clinical significance of cardiovascular dysmetabolic syndrome cv-peptide-Early decline in the catecholamine release-inhibitory peptide catestatin inf hypertension cv-peptide-Essential Role of Monocyte Chemoattractant Protein-1 in Development of Restenotic Changes cv-peptide-ETB Receptor in Renal Medulla Is Enhanced by Local Sodium During Low Salt Intake cv-peptide-Ghrelin, growth and obesity cv-peptide-Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons cv-peptide-Hemodynamic consequences of neuropeptide Y-induced obesity cv-peptide-Hypoxia and HIF-1 Stability cv-peptide-Inhibition of Cyclooxygenase-2 by Natriuretic Peptides cv-peptide-Interleukin-18 Is a Strong Predictor of Cardiovascular Death in Stable and Unstable Angina cv-peptide-Is the Pregnancy Hormone Relaxin Also a Vasodilator Peptide Secreted by the Heart cv-peptide-Long-Term Adrenomedullin Infusion Improves Survival in Malignant Hypertensive Rats cv-peptide-Marinobufagenin, an endogenous ligand of alpha-1 sodium pump, is marker of heart failure cv-peptide-Modulation of nephrin in the diabetic kidney cv-peptide-Molecular forms of adrenomedullin in pericardial fluid and plasma in ischaemic heart disease cv-peptide-Oestrogen action on the myocardium in vivo-ACEI cv-peptide-Protection of Myocytes From Hypoxia-Reoxygenation Injury by Nitric Oxide Is Mediated by Modulation of Transforming Growth Factor-beta1 cv-peptide-Regulation of apoptosis by vasoactive peptides cv-peptide-Role of bombesin-related peptides in the mediation or integration of the stress response cv-peptides-Control of Renin Secretion From Rat Juxtaglomerular Cells by cAMP-Specific Phosphodiesterases cv-peptide-Two Novel Transcripts for Human Endothelin B Receptor Produced by RNA Editing-Alternative Splicing from a Single Gene cv-peptide-Vasoactive intestinal peptide in the immune system cv-peptide-Vasoactive Intestinal Polypeptide Type-1 Receptor Regulation back

更新于2002-10-20