Genomics & Proteomics




Proteome and Genome
DNA微阵列技术等新奇而有效的方法的出现使原始的对生物学功能的研究过渡到了对基因组和蛋白组序列分析的研究，可以说这种转变不仅带来了一次生物学的革命而且为临床疾病的诊断和治疗提供了不可多得的参考。下面将有关蛋白质组和基因组的报道列举如下，更多的文献请查阅cmbi的“综述查询”及相关的栏目（insight）：
Proteome and Proteomics for the Research on Protein Alterations in Aging proteome-Genetic analysis of the mouse brain proteome proteome-proteasomal protein processing proteome-Specificity and Stability in Topology of Protein Networks proteome-Comparative assessment of large-scale data sets of protein–protein interactions proteome-drug discovery-Prioritizing the proteome-identifying pharmaceutically relevant targets proteome-Functional proteomics proteome-Genomics and proteomics of allergic disease proteome-Interrogating protein interaction networks through structural biology proteome-Kit and kits for proteomics, genomics proteome-Noninvasive imaging of protein-protein interactions in living animals Proteomics Analysis of Cellular Response to Oxidative Stress proteome-bi-Proteome Analysis Database proteome-Cardiovascular Proteomics-Evolution and Potential proteome-Comparative assessment of large-scale data sets of protein–protein interactions proteome-cv-Acute-Phase Proteins Before Cerebral Ischemia in Stroke-Prone Rats proteome-cv-Applied Proteomics-Mitochondrial Proteins and Effect on Function proteome-cv-Cardiovascular Proteomics-Evolution and Potential proteome-cv-Proteomic Analysis of Pharmacologically Preconditioned Cardiomyocytes Reveals Novel Phosphorylation of Myosin Light Chain 1 proteome-Global Analysis of Protein Activities Using Proteome Chips Proteome Analysis and Morphological Studies Reveal Multiple Effects of the Immunosuppressive Drug Mycophenolic Acid Specifically Resulting from Guanylic Nucleotide Depletion Proteome-Mass Spectrometry of the Proteome Proteome, transcriptome and genome-top down or bottom up analysis proteome-A Physicist-Turned-Biologist proteome-A Proteomic View on Genome-Based Signal Peptide Predictions proteome-Abundant protein domains occur in proportion to proteome size proteome-Advances in Proteome Analysis by Mass Spectrometry proteome-distinct repertoire of autoantibodies in hepatocellular carcinoma identified by proteomic analysis proteome-Gene and Protein Patents Get Ready to Go Head to Head proteome-High-Speed Biologists Search for Gold in Proteins Proteome-Is There a Bias in Proteome Research proteome-l-From genes to proteins-High-throughput expression and purification of the human proteome proteome-Searching for Recipes for Protein Chips Proteomics-a technology-driven and technology-limited discovery science Proteomics-High-Throughput Proteomics-Protein Expression and Purification in the Postgenomic World Proteomics in Neuroscience-From Protein to Network Proteomics-posttranslational modifications, immune responses and current analytical tools Proteomics Upstart Tries to Outrun the Competition proteomics-An evaluation of the use of two-dimensional gel electrophoresis in proteomics proteomics-Bioinformatics in proteomics proteomics-Errors in genomics and proteomics proteomics-Functional proteomics-large-scale analysis of protein kinase activity Proteomics-PROfusionTM-Genetically Tagged Proteins for Functional Proteomics proteomics-Recent developments in computational proteomics proteomics-The human proteomics initiative (HPI), proteomics-The life of proteins proteomics-The role of mass spectrometry in proteome studies proteomics-Trends in proteomics proteome-Charting the Protein Complexome in Yeast by Mass Spectrometry proteome-Chemical Approaches for Functionally Probing the Proteome proteome-Fully Automated Two-dimensional Capillary Electrophoresis for High Sensitivity Protein Analysis proteome-Genome-wide Study of Gene Copy Numbers, Transcripts, and Protein Levels in Pairs of Non-invasive and Invasive Human Transitional Cell Carcinomas proteome-Proteomic Approach for the Identification of Cell-surface Proteins Shed by Metalloproteases proteome-Quantitative Protein Profiling Using Two-dimensional Gel Electrophoresis, Isotope-coded Affinity Tag Labeling, and Mass Spectrometry proteome-Vascular Proteomics and Subtractive Antibody Expression Cloning proteome-An NMR approach to structural proteomics proteome-Development of an optimized interaction-mating protocol for large-scale yeast two-hybrid analyses proteome-Survey of human mitochondrial diseases using new genomic-proteomic tools Proteomics-Boom or Bust proteome-Selective Detection of Membrane Proteins Without Antibodies-A Mass Spectrometric Version of the Western Blot proteome-2D Differential In-gel Electrophoresis for the Identification of Esophageal Scans Cell Cancer-specific Protein Markers proteome-Application of Microfluidic Devices to Proteomics Research proteome-Combinatorial Selection of RNA Ligands for Complex Cellular Targets-The RNA Liagands-Based Proteomics proteome-Describing Biological Protein Interactions in Terms of Protein States and State Transitions-THE LiveDIP DATABASE proteome-Evaluation of Two-dimensional Differential Gel Electrophoresis for Proteomic Expression Analysis proteome-Getting More from Less-Algorithms for Rapid Protein Identification with Multiple Short Peptide Sequences proteome-Hydrogen Exchange-Mass Spectrometry proteome-Kinetic studies of protein¨Cprotein interactions proteome-Prediction of protein¨Cprotein interactions by docking methods proteome-Protein¨Cnucleic acid interactions proteome-Protein¨Cprotein association kinetics and protein docking Proteome-scale purification of human proteins from bacteria proteome-What does it mean to identify a protein in proteomics Proteome-Vascular Proteomics and Subtractive Antibody Expression Cloning proteome-the quest for multiplexed fluorescence quantitative analysis in proteomics proteome-Accelerating code to function-sizing up the protein production line proteome-Applied Proteomics-Mitochondrial Proteins and Effect on Function proteome-Charting the Protein Complexome in Yeast by Mass Spectrometry proteome-Clinical and functional target validation using tissue and cell microarrays proteome-Current achievements using ProteinChip Array technology proteome-Emerging array-based technologies in proteomics proteome-Fully Automated Two-dimensional Capillary Electrophoresis for High Sensitivity Protein Analysis proteome-Functional protein microarrays proteome-Genome and protein evolution in eukaryotes proteome-Lab-on-a-chip-applications in proteomics proteome-Miniaturised multiplexed immunoassays proteome-One from column A and two from column B-the benefits of phage display in molecular-recognition studies proteome-perspective on protein microarrays proteome-Phosphoproteome analysis by mass spectrometry proteome-Protein transduction technology proteome-Systems Biology-A Brief Overview proteome-transorientation hypothesis for codon recognition during protein synthesis proteome-Two-dimensional gel electrophoresis proteome-Two-hybrid arrays proteome-Yeast mitochondrial biogenesis-a model system for humans Proteome and Proteomics for the Research on Protein Alterations in Aging proteome-Pharmaceutical Proteomics proteome-Circular proteins ?a no end in sight proteome-Protein microarray technology proteome-Synthesis Beyond the Molecule Proteomics of the nucleolus-more proteins, more functions proteome-Combinatorial Selection of RNA Ligands for proteome-Evaluation of Two-dimensional Differential Gel Electrophoresis for Proteomic Expression Analysis proteome-Genetic analysis of the mouse brain proteome proteome-Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases proteome-In Situ Tracking of protein traffiking proteome-'periodic table for protein structures proteome-Evolutionary Rate in the Protein Interaction Network proteome-Systems biology-The reincarnation of systems theory applied in biology proteome-distinct repertoire of autoantibodies in hepatocellular carcinoma identified by proteomic analysis proteome-A computational approach to identify genes for functional RNAs in genomic sequences proteome-A Distinct Repertoire of Autoantibodies in Hepatocellular Carcinoma Identified by Proteomic Analysis proteome-A Proteomic Approach for Identification of Secreted Proteins during the Differentiation of 3T3-L1 Preadipocytes to Adipocytes proteome-A strategy for the rapid identification of phosphorylation sites in the phospho-proteome proteome-Analysis of mammalian peroxin interactions using a non-transcription-based bacterial two-hybrid assay proteome-Convergent evolution with combinatorial peptides proteome-Deciphering protein complexes and protein interaction networks by tandem affinity purification and mass spectrometry-Analytical perspective proteome-Deciphering Protein Complexes and Protein Interaction Networks by Tandem Affinity Purification and Mass Spectrometry proteome-Differential proteome analysis of replicative senescence in rat embryo fibroblasts proteome-Discordant protein and mRNA expression in lung adenocarcinomas proteome-Domain repertoires as a tool to derive protein recognition rules proteome-Functional genomics by mass spectrometry proteome-Gene expression data analysis proteome-Gene expression profiling-monitoring transcription and translation products using DNA microarrays and proteomics proteome-Gene trap-a way to identify novel genes and unravel their biological function proteome-Genome-wide protein interaction maps using two-hybrid systems proteome-Isolation of Protein Subpopulations Undergoing Protein-Protein Interactions proteome-Protein interactions-Two methods for assessment of the reliability of high-throughput observations proteome-Protein structure comparison using bipartitegraph matching and its application to proteinstructure classification proteome-Proteomic analysis of shrimp white spot syndrome viral proteins proteome-Proteomic strategies to reveal tumor heterogeneity among urothelial papillomas proteome-Systematic identification of protein-protein interactions by mass spectrometry proteome-THE RAPID EVOLUTION OF REPRODUCTIVE PROTEINS proteome-Tools of the proteomics trade Proteomics-Boom or Bust Proteomics-New perspectives, new biomedical opportunities cv-proteome-Conserved Cardiogenic Functions of the Multitype Zinc-Finger Proteins cv-proteome-Acute-Phase Proteins Before Cerebral Ischemia in Stroke-Prone Rats cv-proteome-Genomics and Hypertension cv-proteome-In Search of the Proteins That Cause Myocardial Stunning cv-proteome-Use of functional proteomics to investigate PKC-mediated cardioprotection cv-proteome-Genetic Approach to Detect Muscle Protein Interactions in vivo genome-ALU REPEATS AND HUMAN GENOMIC DIVERSITY genome-cell-Specificity of Gene Regulation genome-Estimating the Human Gene Count genome-Human genetics-Dual identities genome-Regulation of noise in the expression of a single gene genome-Regulation of noise in the expression of a single gene genome-Antioxidant-induced changes in oxidized DNA genome-Combinatorial Synthesis of Genetic Networks genome-Evolutionary genetics-All genomes great and small genome-Finding the crosswalks on DNA genome-Keeping the genome in shape genome-The identification of functional modules from the genomic association of genes genome-The Human Genome Project-the next decade genome-Form and function in the human interphase chromosome genome-Talking Gene Patents genome-FISH-based genome analysis genome-Microsatellite instability genomics-Lessons from the human genome-transitions between euchromatin and heterochromatin Genome and hormones-an integrated approach to gender differences in physiology genome-Decoding the human genome sequence genome rearrangements-environmental and genetic effects Genome sequencing networks genome-Short cut to disease genes genome-A genomic timescale for the origin of eukaryotes genome-Adaptive hitchhiking effects on genome variability genome-Advances in the detection of chromosomal aberrations using spectral karyotyping genome-Alternative splicing and genome complexity genome-Analysis of the sheep genome genome-Cloning of Aged Animals; A Medical Model for Tissue and Organ genome-Deciphering genetic regulatory codes-A challenge for functional genomics Genome-Disease Maps of the Human Genome-10 Genome-Disease Maps of the Human Genome-11 genome-Dissecting a population genome for targeted screening of disease mutations genome-DISSEMINATING THE GENOME-Joining, Resolving, and Separating Sister Chromatids During Mitosis and Meiosis genome-Embryogenomics-developmental biology meets genomics genome-Evolution of mammalian genome organization inferred from comparative gene mapping genome-Evolution of novel genes genome-Evolving Genomic Metaphors-A New Look at the Language of DNA genome-Extensively overlapping reading frames in a second mammalian gene genome-function genome genome-Functional Genomics, Gene Arrays, and the Future of Pathology genome-Gene expression and molecular evolution genome-Gene regulation-Code of silence genome-Genetic diseases of hemoglobin genome-Genetic diversity and disease-Opportunities and challenge genome-Genomic and Genetic Definition of a Functional Human Centromere genome-Global Efforts in Structural Genomics genome-Haemochromatosis-novel gene discovery and the molecular pathophysiology of iron metabolism genome-Harnessing Genomics and Biotechnology to Improve Global Health Equity genome-Historic genomics-an emergent discipline genome-Human genetic research, DNA banking and consent genome-Human genetics-Testing telomerase Genome-Human Genome-An Introduction genome-Human Genome and Diseases Genome-Human Genome Project genome-human genome-Part three in the book of genes genome-In our genes genome-Intraepithelial gd T cells exposed by functional genomics genome-Major genomic mitochondrial lineages delineate early human expansions genome-Making Sense of Eukaryotic DNA Replication Origins genome-microarray-Characterization of the expression ratio noise structure in high-density oligonucleotide arrays genome-mitochondrial genome-mutation, selection and recombination Genome-Most of the Human Genome Is Transcribed genome-Multicultural education and genetic counseling genome-Multicultural genetic counseling-Then, now, and in the 21st century genome-Muscular Dystrophy Meets the Gene Chip-New Insights into Disease Pathogenesis genome-Mutation rates in mammalian genomes genome-Nucleomorph genomes-much ado about practically nothing genome-Of Mice and Genome Sequence genome-Postgenomics-Data, data, everywhere... genome-Progress in sequencing the mouse genome genome-Protein Structure Prediction and Structural Genomics genome-Quality control in the discovery, reporting, and recording of genomic variation genome-Recent duplication, domain accretion and the dynamic mutation of the human genome genome-Reconstructing-Deconstructing the Earliest Eukaryotes-How Comparative Genomics Can Help genome-Replication Dynamics of the Yeast Genome genome-Reprogramming of genome function through epigenetic inheritance genomes-Deletional bias and the evolution of bacterial genomes genomes-Disease Maps of the Human Genome-12 genomes-DNA loops and semicatenated DNA junctions genome-Securing genome stability by orchestrating DNA repair genome-Sequence variation and disease in the wake of the draft human genome genome-sexually transmitted genome genomes-Functional associations of proteins in entire genomes by means of exhaustive detection of gene fusions genomesFunctional genomics and metal metabolism genomes-Impact of genomics on drug discovery and clinical medicine genomes-Interrelating Different Types of Genomic Data, from Proteome to Secretome genomes-Membrane traffic between genomes genomes-Mining mouse microarray data genomes-Nucleomorph genomes-much ado about practically nothing genome-Targeted gene regulation and gene ablation Genome-Testing the Parsimony Test of Genome Duplications genome-The Evolution of Controlled Multitasked Gene Networks-The Role of Introns and Other Noncoding RNAs in the Development of Complex Organisms genome-The Human Genome Revealed genome-The role of genomic imprinting in human developmental disorders genome-Triplex forming oligonucleotide-sequence-specific tools for gene targeting genome-vivo Modulation of Human-globin Gene Switching genome-What controls the length of noncoding DNA Genome-wide analysis of protein-DNA interactions in living cells Genome-wide variation in the human and fruitfly-a comparison genome-Zebrafish-bridging the gap between development and disease Genomic analysis of metastasis reveals an essential role for RhoC Genomic-Annotation Transfer for Genomics-Measuring Functional Divergence in Multi-Domain Proteins Genomic-Automation for Genomics, Part One-Preparation for Sequencing Genomic-Automation for Genomics, Part Two-Sequencers, Microarrays, and Future Trends Genomic change and gene silencing in polyploids Genomic-Evolution and Variation of the Yeast (Saccharomyces) Genome Genomic-Genomic Approaches to Understanding Asthma Genomic Imprinting-Implications for Human Disease Genomic medicine-Who will practice it-A call to open arms Genomic-Minisatellites-Mutability and Genome Architecture Genomic-Pyrosequencing Sheds Light on DNA Sequencing Genomic-Structure of Chromosomal Duplicons and their Role in Mediating Human Genomic Disorders genomic view of alternative splicing Genomic-Categorizing genetic tests to identify their ethical, legal, and social implications Genomic-Empowering primary care health professionals in medical genetics genomic-neutral theory in the genomic era genomic-Odorant receptor gene regulation-implications from genomic organization Genomics and future biological weapons-the need for preventive action by the biomedical genomics-Beyond genomics genomics-Chemical genomics-Functional analysis of orphan nuclear receptors in the regulation of bile acid metabolism Genomics-Chip Shots-Will Functional Genomics Get Functional genomics-Phage Genomics-Small Is Beautiful genomics-Population genomics genomics-Structural genomics and signaling domains genomic-Travelling the genomic road Genome sequencing-Brouhaha over the other yeast genome-Current status of human chromosome 14 genome-Monoclonal mice generated by nuclear transfer from mature B and T donor cells genome-Nuclear transplantation-A monoclonal mouse genome-Origins of Human Virus Diversity genome-Secret life of genes genome-The past, present and future of genome-wide re-annotation geneome-Supervised harvesting of expression trees genome-A clustering method for repeat analysis in DNA sequences genome-A draft annotation and overview of the human genome genome-Current status of human chromosome 14 genome-opposite of genomics. genome-Applying genomics technologies to neural development genome-Functional genomics of critical illness and injury genomes-Haemochromatosis-Understanding the mechanism of disease and implications for diagnosis and management Genome-Regulatory Network for Development genome-A CLASSIC MODEL ENTERS THE ERA OF FUNCTIONAL GENOMICS genome-Are there any normal cloned mammals genome-Chemical genomics-discovery of disease genes and drugs genome-FROM SEQUENCE TO PHENOTYPE genome-How to publish DNA sequences with copyright protection genome-Human gene discovery through experimental definition of transcribed regions of the human genome genome-Large-scale genotyping by mass spectrometry genome-On the sequencing of the human genome genome-Splicing regulation as a potential genetic modifier genome-THE ART AND DESIGN OF GENETIC SCREENS genome-Ethical Issues in Human Genome Epidemiology genome-An extensive network of coupling among gene expression machines genome-On the sequencing and assembly of the human genome Whole-genome disassembly-Whole-genome disassembly genome-Alternative splicing-multiple control mechanisms and involvement in human disease genome-PATTERNS OF LINKAGE DISEQUILIBRIUM IN THE HUMAN GENOME genome-The sterol-sensing domain-multiple families, a unique role genome-A Crisis in Postgenomic Nomenclature genome-Balancing Life-Style and Genomics Research for Disease Prevention genome-Alternative splicing-multiple control mechanisms and involvement in human disease genome-Are there any normal clones mammals genome-Biodiversity-Microbial genomes multiply genome-Caretaker tumour suppressor genes that defend genome integrity genome-Challenges for the genomics era genome-Epigenetics is seen as possible key to cloning genome-Eugenic danger or genetic promise-A revolution for the millennium , genome-Four years of post-genomic life with 6000 yeast genes genome-FROM SEQUENCE TO PHENOTYPE-REVERSE GENETICS IN DROSOPHILA MELANOGASTER genome-Gene expression profile analysis by DNA microarrays-Promise and pitfalls genome-Gene flow and the limits to natural selection genome-Genomic and phylogenetic perspectives on the evolution of prokaryotes , genome-Human gene mutations causing infertility genome-Implications of the human genome for understanding human biology and medicine , genome-Intra-and Interspecific Variation in Primate Gene Expression Patterns genome-Milestone or genomania-The relevance of the human genome project to biological aging genome-Molecular indexing of human genomic DNA genome-NOT YOUR FATHER??￥S PLANARIAN-A CLASSIC MODEL ENTERS THE ERA OF FUNCTIONAL GENOMICS genome-Recent developments and future directions in computational genomics genome-The anatomy of the human genome-A neo-Vesalian basis for medicine in the 21st century genome-THE ART AND DESIGN OF GENETIC SCREENS-ARABIDOPSIS THALIANA genome-THE ART AND DESIGN OF GENETIC SCREENS-DROSOPHILA MELANOGASTER genome-THE COMPLEX STRUCTURE AND DYNAMIC EVOLUTION OF HUMAN SUBTELOMERES genome-The genome doctor genome-THE MOUSE-GENETICS MEETS BEHAVIOUR Genomics-The Science and Technology Behind the Human Genome Project , Genomics-Implications for health systems-The effect of genomics on health services management-Ethical and genome-Rice Genome-Collaborating on the Rice Genome genome-Rice Genome-Why Finishing the Rice Genome Matters genome-Rice Genome-A Deal for the Rice Genome genome-Rice Genome-A Draft Sequence of the Rice Genome-I genome-Rice Genome-A Draft Sequence of the Rice Genome-II genome-Rice Genome-Agreement (and associated documents) between Syngenta and AAAS regarding access to data supporting the Goff et al.study-I genome-Rice Genome-Agreement (and associated documents) between Syngenta and AAAS regarding access to data supporting the Goff et al.study-II genome-Rice Genome-Beijing Genomics Institute_From Standing Start to Sequencing Superpower genome-Rice Genome-Functional Annotation of a Full-Length Arabidopsis cDNA Collection genome-Rice Genome-Mapping and Sequencing the Rice Genome genome-Rice Genome-Opening the Door to Comparative Plant Biology genome-Rice Genome-Rice_Boiled Down to Bare Essentials genome-Rice Genome-The Cereal of the World's Poor Takes Center Stage genome-Rice Genome-The Importance of Rice genome-Rice Genome-The Most Precious Things Are Not Jade and Pearls... genome-Rice Genome-The Rice Chromosomes genome-Rice Genome-World Poverty and Hunger-the Challenge for Science Genome and Hormones-Gender Differences in Physiology-Historical Perspectives Genome and Hormones-Gender Differences in Physiology-An abridged history of sex steroid hormone receptor action Genome and Hormones-Gender Differences in Physiology-Association of gender-related LMP2 inactivation with autoimmune pathogenesis Genome and Hormones-Gender Differences in Physiology-Cardiovascular protective effects of 17-estradiol metabolites Genome and Hormones-Gender Differences in Physiology-Cell localization, physiology, and nongenomic actions of estrogen receptors Genome and Hormones-Gender Differences in Physiology-Cerebrovascular NOS and cyclooxygenase are unaffected by estrogen Genome and Hormones-Gender Differences in Physiology-Effects of gender on reduced-size liver ischemia and reperfusion injury Genome and Hormones-Gender Differences in Physiology-Effects of sex and ovariectomy on responses to platelets in porcine femoral veins Genome and Hormones-Gender Differences in Physiology-Estrogen receptor-antisense decreases brain estrogen receptor levels and affects ventilation Genome and Hormones-Gender Differences in Physiology-Estrogen receptor-gene transfer inhibits proliferation and NF-B activation in VSM cells Genome and Hormones-Gender Differences in Physiology-Estrogens effects on the brain-multiple sites and molecular mechanisms Genome and Hormones-Gender Differences in Physiology-Gender differences in cardiovascular regulation during recovery from exercise Genome and Hormones-Gender Differences in Physiology-Gender differences in the endothelin-B receptor contribution to basal cutaneous vascular tone in humans Genome and Hormones-Gender Differences in Physiology-Gender issues related to spaceflight Genome and Hormones-Gender Differences in Physiology-Genome and hormones-an integrated approach to gender differences in physiology Genome and Hormones-Gender Differences in Physiology-Pharmacogenetics of estrogen replacement therapy Genome and Hormones-Gender Differences in Physiology-Sex differences in osmotic regulation of AVP and renal sodium handling Genome and Hormones-Gender Differences in Physiology-Sex ratio and rheumatic disease Genome and Hormones-Gender Differences in Physiology-Sex-based differences in gene expression cv-genome--Genetic analysis for common complex disease cv-genome--Genetic susceptibility to cardiovascular diseases cv-genome--Genetics, genomics, proteomics-What is a cardiologist to do cv-genome-A Genomic-Systems Biology Map for Cardiovascular Function cv-genome-Integrating genomics technologies in health care-practice and policy challenges and opportunities cv-genome-Autosomal Genome-Wide Scan for Coronary Artery Calcification Loci in Sibships at High Risk for Hypertension
更新于2002-06-04