Cancer Stem Cells

       随着干细胞生物学研究领域的日趋成熟，科学家们逐渐从对造血系统中存在干细胞的研究转向对一些组织特异性干细胞和祖细胞的分离与研究、对它们的特征和基因表达程序的阐述，以及在再生医学中对它们应用的研究。众所周知干细胞的自我更新能力是其最重要和最有用的特征。通过这一特征能够发现干细胞和癌细胞之间有惊人的相似：肿瘤可能通常起源于正常干细胞的转化，相似的信号通路可能既调节干细胞也调节癌细胞的自我更新。现已发现一些癌细胞中包含有肿瘤干细胞（cancer stem cells）----它们是一些极少的具有自我更新不定潜能的驱使肿瘤形成的细胞。为此CMBI特别做了这期特别报道供大家参考。另：在此之前我们曾做过关于"神经干细胞"、"心脏干细胞"及其它干细胞相关报道，参见特别报道第109期、第113期、第10期和第39期。 更多的资料，请用相关的关键词通过CMBI文献查询获取。

肿瘤干细胞

• Immunotherapy of tumors using bone marrow transplantation with antigen gene–modified stem cells
• Chemotherapy Plus Stem-Cell Rescue For High-Risk Breast Cancer
• High-Dose Chemotherapy And Stem-Cell Transplantation In Stage Ii Or Iii Breast Cancer
• High-Dose Chemotherapy With Hematopoietic Stem-Cell Rescue For High-Risk Breast Cancer
• Stem-Cell Transplantation For High-Risk Breast Cancer
• Stem-Cell Transplantation For High-Risk Breast Cancer-
• Umbilical-Cord Blood Transplantation For The Treatment Of Cancer
• CONTRIBUTION OF STEM CELLS AND DIFFERENTIATED CELLS TO EPIDERMAL TUMOURS
• STEM-CELL HIERARCHY IN SKIN CANCER
• Breast cancer stem cells revealed
• High Dose Chemotherapy and Stem Cell Support in the Treatment of Germ Cell Cancer
• Liver transplantation followed by adjuvant hemopoietic stem cell transplantation for liver cancer
• The Role of Stem Cells and Gap Junctional Intercellular Communication in Carcinogenesis
• A non-Darwinian role for mutagenesis in stem cell-derived cancers
• Critical review on non-myeloablative stem cell transplantation
• Stem-cell origin of metastasis and heterogeneity in solid tumours
• pathol-mol-Field cancerization, clonality, and epithelial stem cells
• Stem cells, cancer, and cancer stem cells
• Hematological Cancer- Elderly Patients Can Benefit From Stem Cell Autotransplants
• Incidence of Tumor-Cell Contamination in Leukapheresis Products of Breast Cancer Patients Mobilized With Stem Cell Factor and Granulocyte Colony-Stimulating Factor (G-CSF) or With G-CSF Alone
• Incidence of Tumor-Cell Contamination in Leukapheresis Products of Breast Cancer Patients Mobilized With Stem Cell Factor and Granulocyte Colony-Stimulating Factor (G-CSF) or With G-CSF Alone
• ca-DNA methylation and cancer-Methylation reveals a niche-stem cell succession in human colon crypts
• ca-Progenitor Cell Content of Blood Stem Cell Harvests in Breast Cancer
• PERIPHERAL BLOOD STEM CELL TRANSPLANTATION-NON-MYELOABLATIVE STEM CELL TRANSPLANTATION AND DONOR LYMPHOCYTE INFUSION FOR THE TREATMENT OF CANCER
• Progenitor Cell Content of Blood Stem Cell Harvests in Breast Cancer
• ca-cell-A non-Darwinian role for mutagenesis in stem cell-derived cancers
• Can neural stem cells be used to track down and destroy migratory brain tumor cells while also providing a means of repairing tumor-associated damage
• Can neural stem cells be used to track down and destroy migratory brain tumor cells while also providing a means of repairing tumor-associated damage
• PTEN-Coupling Tumor Suppression to Stem Cells
• ca-High-dose chemotherapy with autologous stem cell rescue for brain tumors
• Incidence of Tumor-Cell Contamination in Leukapheresis Products of Breast Cancer Patients Mobilized With Stem Cell Factor and Granulocyte Colony-Stimulating Factor (G-CSF) or With G-CSF Alone
• Incidence of Tumor-Cell Contamination in Leukapheresis Products of Breast Cancer Patients Mobilized With Stem Cell Factor and Granulocyte Colony-Stimulating Factor (G-CSF) or With G-CSF Alone
• allogeneic stem cell transplantation-Nonmyeloablative stem cell transplantation for solid tumors
• Stem cell and gene therapy-Molecular basis of co-targeting prostate tumor and stroma
• Stem cell biology and gene therapy-Molecular basis of co-targeting prostate tumor and stroma
• Tumor suppressor gene BRCA-1 is expressed by embryonic and adult neural stem cells
• Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
• Pediatric-Hematology and oncology-Novel conditioning regimens and nonmyeloablative stem cell transplants
• Neural stem cells and neuro-oncology
• Neural stem cells and neuro-oncology
• Neural stem cells and neuro-oncology
• ca-Autologous SCT for Small Cell Lung Cancer

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