Atrial natriuretic peptide



心钠素
心钠素是1984年被发现的、由心肌细胞分泌的一种调节肽。心钠素的发现奠定了心脏内分泌学的重要基础。心钠素分布广泛、进化保守、是有多种功能的一个调节多肽家族。心钠素30年的研究涉及分子生物学、功能、结构和功能活性的关系、分类等多方面。尤其是近年来关于心钠素在临床诊断和治疗中的作用有新的认识。目前心钠素信号传导的分子生理学研究、心钠素血管活性研究、心钠素在缺血心肌中的调节作用、心钠素在心衰诊断、预后和治疗中作用的研究都是热点研究问题。为此CMBI特为大家准备了关于心钠素的最新文献供研究参考，更多文献,请用相关关键词通过CMBI文献查询获取。
Obesity and suppressed B-type natriuretic peptide levels in heart failure Natriuretic peptides as markers of preclinical cardiac disease in obesity Increased Atrial and Brain Natriuretic Peptides in Adults With Cyanotic Congenital Heart Disease Crystal Structure of Hormone-bound Atrial Natriuretic Peptide Receptor Extracellular Domain B-type natriuretic peptide and peak exercise oxygen consumption provide independent information for risk stratification in patients with stable congestive heart failure B type natriuretic peptide testing Augmentation of moxonidine-induced increase in ANP release by atrial hypertrophy Alterations in atrial natriuretic peptide and its receptors in streptozotocin-induced diabetic rat Sphingosine-1-Phosphate Inhibits C-Type Natriuretic Peptide Activation of Guanylyl Cyclase B Selective upregulation of cardiac brain natriuretic peptide at the transcriptional and translational levels by pro-inflammatory cytokines Natriuretic Peptides Predict Symptom-Free Survival and Postoperative Outcome in Severe Aortic Stenosis Effects of Exogenous and Endogenous Natriuretic Peptides on Forearm Vascular Function in Chronic Heart Failure Brain natriuretic peptide levels during cardiac reperfusion Atrial natriuretic peptide influence on nitric oxide system in kidney and heart The natriuretic peptides-Vascular actions of natriuretic peptides-Cyclic GMP-dependent and-independent mechanisms The natriuretic peptides-The natriuretic peptides in heart failure The natriuretic peptides-Natriuretic peptides and myocardial ischaemia The natriuretic peptides-Molecular physiology of natriuretic peptide signalling The natriuretic peptides-An introduction Small HDL form via apo A-I a complex with atrial natriuretic peptide Selective upregulation of cardiac brain natriuretic peptide at the transcriptional and translational levels by pro-inflammatory cytokines Plasma cardiac natriuretic peptide levels in screening for cardiac disease Is b-type natriuretic peptide a useful screening test for systolic or diastolic dysfunction in patients with coronary disease genetics-Atrial Natriuretic Peptide Gene Polymorphisms and Risk of Ischemic Stroke in Humans Diagnostic value of B-Type natriuretic peptide and chest radiographic findings in patients with acute dyspnea Comparison of B-type natriuretic peptide levels in patients with heart failure Brain Natriuretic Peptide Enhances Renal Actions of Furosemide and Suppresses Furosemide-Induced Aldosterone Activation in Experimental Heart Failure Atrial natriuretic peptide influence on nitric oxide system in kidney and heart Atrial Natriuretic Peptide Gene Polymorphisms and Risk of Ischemic Stroke in Humans Association of plasma atrial natriuretic peptide, n-terminal proatrial natriuretic peptide, and brain natriuretic peptide levels with coronary artery stenosis Volume overload results in exaggerated cardiac hypertrophy in the atrial natriuretic peptide knockout mouse ventricular contractile reserve during low dose dobutamine echocardiography and natriuretic peptides N-terminal proANP-Value of N-terminal pro brain natriuretic peptide in the elderly N-terminal proANP-Use of NT-proBNP in routine testing and comparison to BNP N-terminal proANP-NT-proBNP in unstable coronary artery disease-experiences from the FAST, GUSTO IV and FRISC II trials N-terminal proANP-NT-proBNP in severe chronic heart failure N-terminal proANP-NT-proBNP in heart failure-therapy decisions and monitoring N-terminal proANP-NT-proBNP and the diagnosis of heart failure-a pooled analysis of three European epidemiological studies N-terminal proANP-NT-proBNP and BNP-biomarkers for heart failure management N-terminal proANP-N-terminal probrain natriuretic peptide (NT-proBNP) in the emergency diagnosis and in-hospital monitoring of patients with dyspnoea and ventricular dysfunction N-terminal proANP-N-terminal proBNP and mortality in hospitalised patients with heart failure and preserved vs. reduced systolic function N-terminal proANP-N-terminal pro brain natriuretic peptide in arterial hypertension-a marker for left ventricular dimensions and prognosis N-terminal proANP-Natriuretic peptides for risk stratification of patients with acute coronary syndromes N-terminal proANP-Natriuretic peptides for heart failure N-terminal proANP-Essential biochemistry and physiology of (NT-pro)BNP N-terminal proANP-Can natriuretic peptides be used for the diagnosis of diastolic heart failure N-terminal proANP-Brain and other natriuretic peptides-molecular aspects N-terminal proANP-Biological variation of the natriuretic peptides and their role in monitoring patients with heart failure N-terminal proANP-Application of NT-proBNP and BNP measurements in cardiac care N-terminal proANP-Analytical performance of the N terminal pro B type natriuretic peptide (NT-proBNP) assay Effect of exercise on natriuretic peptides in plasma and urine in chronic heart failure Diagnostic and prognostic evaluation of left ventricular systolic heart failure by plasma N-terminal pro-ANP cell-B-Type Natriuretic Peptide Exerts Broad Functional Opposition to Transforming Growth Factor-β in Primary Human Cardiac Fibroblasts Brain natriuretic peptide-A marker of myocardial dysfunction and prognosis during severe sepsis Autocrine and paracrine actions of natriuretic peptides in the heart Vascular actions of natriuretic peptides-Cyclic GMP-dependent and-independent mechanisms Use of B-Type Natriuretic Peptide in the Evaluation and Management of Acute Dyspnea The natriuretic peptides in heart failure The natriuretic peptides-An introduction The effect of class-specific protease inhibitors on the stabilization of B-type natriuretic peptide in human plasma Prognostic information provided by serial measurements of brain natriuretic peptide in heart failure Plasma Natriuretic Peptide Levels and the Risk of Cardiovascular Events and Death--- N-terminal pro-brain natriuretic peptide for discriminating between cardiac and non-cardiac dyspnoea Natriuretic peptides and myocardial ischaemia mecular physiology of natriuretic peptide signalling Impact of Obesity on Plasma Natriuretic Peptide Levels Forced Homodimerization by Site-Directed Mutagenesis Alters Guanylyl Cyclase Activity of Natriuretic Peptide Receptor B ECG and brain natriuretic peptide as indicators of left ventricular systolic dysfunction Diagnostic value of a rapid test for B-type natriuretic peptide in patients presenting with acute dyspnoe C-type natriuretic peptide in reproduction, pregnancy and fetal development B-Type Natriuretic Peptide Exerts Broad Functional Opposition to Transforming Growth Factor-in Primary Human Cardiac Fibroblasts. Fibrosis, Myofibroblast Conversion, Proliferation, and Inflammation B-Type Natriuretic Peptide — A Biomarker for All Seasons Attenuation of Lysophosphatidylcholine-Induced Suppression of ANP Release From Hypertrophied Atria Role of the Natriuretic Peptide System in Cardiorenal Protection Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathway Multicenter evaluation of the Roche NT-proBNP assay and comparison to the Biosite Triage BNP assay Involvement of atrial natriuretic peptide in blood pressure reduction induced by estradiol in spontaneously hypertensive rats Hypertension induced by nitric oxide synthase inhibition activates the atrial natriuretic peptide (ANP) system C-type natriuretic peptide induces human colonic myofibroblast relaxation C-type natriuretic peptide decreases soluble guanylate cyclase levels by activating the proteasome pathway C-type natriuretic peptide decreases soluble guanylate cyclase levels by activating the proteasome pathway Should B-Type Natriuretic Peptide Be Measured Routinely to Guide the Diagnosis and Management of Chronic Heart Failure Plasma B-Type Natriuretic Peptide Levels in Ambulatory Patients With Established Chronic Symptomatic Systolic Heart Failure Involvement of a cGMP-dependent Pathway in the Natriuretic Peptide-mediated Hormone-sensitive Lipase Phosphorylation in Human Adipocytes Four functionally distinct C-type natriuretic peptides found in fish reveal evolutionary history of the natriuretic peptide system Effect of Atrial Fibrillation on Hematopoietic Progenitor Cells-A Novel Pathophysiological Role of ANP B-type natriuretic peptide as a noninvasive screening tool for cardiac allograft pathology B-Type Natriuretic Peptide and Ischemia in Patients With Stable Coronary Disease Vascular Natriuretic Peptide Receptor-Linked Particulate Guanylate Cyclases Are Modulated By Nitric Oxide–cyclic Gmp Signalling The Paradox Of Increased Natriuretic Hormones In Congestive Heart Failure Patients Pressure-Independent Enhancement Of Cardiac Hypertrophy In Anp-Deficient Mice Physiological Concentration Of Atrial Natriuretic Peptide Induces Endothelial Regeneration In Vitro Pharmacological Modulation Of The Natriuretic Peptide System Natriuretic Peptides And Acute Renal Failure Natriuretic Peptide Receptor A Mediates Renal Sodium Excretory Responses To Blood Volume Expansion Modulation Of The Natriuretic Peptide System In Heart Failure-From Bench To Bedside Mechanisms Of Renal Hyporesponsiveness To Anp In Heart Failure Inhibition Of L-Type Ca2+ Current By C-Type Natriuretic Peptide In Bullfrog Atrial Myocytes-An Npr-C-Mediated Effect Haemodynamic Action Of B-Type Natriuretic Peptide Substantially Outlasts Its Plasma Half-Life In Conscious Dogs Combination Of B-Type Natriuretic Peptide And Peak Oxygen Consumption Improves Risk Stratification In Outpatients With Chronic Heart Failure B-Type Natriuretic Peptide Limits Infarct Size In Rat Isolated Hearts Via Katp Channel Opening Atrial Natriuretic Peptide Regulates Regional Vascular Volume And Venous Tone In Humans Atrial Natriuretic Peptide Induces Natriuretic Peptide Receptor-Cgmp-Dependent Protein Kinase Interaction Prognostic Usefulness Of An Increase Of N-Terminal Proatrial Natriuretic Peptide During Exercise In Patients With Chronic Heart Failure Pressure Overload On Extracellular Matrix In The Heart Of The Atrial Natriuretic Peptide-Null Mouse Furin-Mediated Processing Of Pro-C-Type Natriuretic Peptide PITX2 Isoform-specific Regulation of Atrial Natriuretic Factor Expression N-terminal proatrial natriuretic peptide in primary care-relation to echocardiographic indices of cardiac function in mild to moderate cardiac disease Comparison of the effects of dobutamine and nesiritide (B-type natriuretic peptide) on ventricular ectopy in acutely decompensated ischemic versus nonischemic cardiomyopathy B-Type Natriuretic Peptides and Ejection Fraction for Prognosis After Myocardial Infarction Brain natriuretic peptide facilitates severity classification of stable chronic heart failure Brain Natriuretic Peptide as a Predictor of Adverse Outcome in Patients With Pulmonary Embolism Increased Sensitivity to Endothelial Nitric Oxide (NO) Contributes to Arterial Normotension in Mice with Vascular Smooth Muscle-selective Deletion of the Atrial Natriuretic Peptide (ANP) Receptor Use of Plasma Brain Natriuretic Peptide Concentration to Aid in the Diagnosis of Heart Failure Triiodothyronine Increases Brain Natriuretic Peptide (BNP) Gene Transcription and Amplifies Endothelin-dependent BNP Gene Transcription and Hypertrophy in Neonatal Rat Ventricular Myocytes Low Pro-Brain Natriuretic Peptide Levels Predict Benign Clinical Outcome in Acute Pulmonary Embolism Increased Plasma Natriuretic Peptide Levels Reflect Symptom Onset in Aortic Stenosis Usefulness of brain natriuretic peptide release as a surrogate marker of the efficacy of long-term cardiac resynchronization therapy in patients with heart failure Significance and therapeutic potential of the natriuretic peptides-cGMP-cGMP-dependent protein kinase pathway in vascular regeneration Natriuretic Peptide Receptor A Activation Stabilizes a Membrane-distal Dimer Interface B-Type natriuretic peptide-From bench to bedside The Basic-Helix-Loop-Helix Transcription Factor HAND2 Directly Regulates Transcription of the Atrial Naturetic Peptide Gene Release of C-type natriuretic peptide accounts for the biological activity of endothelium-derived hyperpolarizing factor NT-proBNP-new diagnostic screening tool between with normal and reduced left ventricular systolic function Myocardial Production of C-Type Natriuretic Peptide in Chronic Heart Failure Inhibitory Effect of ANP on Aldosterone Synthase Gene Expression in Neonatal Rat Cardiocytes Guanylyl Cyclase Receptors Mediate Cardiopulmonary Vagal Reflex Actions of ANP Correlation of B-type natriuretic peptide level to 6-min walk test performance in patients with left ventricular systolic dysfunction BNP test utilization for CHF in community hospital practice B type natriuretic peptide levels had high sensitivity but moderate specificity for detecting CHF Atrial natriuretic factor inhibits mitogen-induced growth in aortic smooth muscle cells Antihypertrophic actions of the natriuretic peptides in adult rat cardiomyocytes Beneficial Effects of Phosphodiesterase 5 Inhibition in Pulmonary Hypertension Are Influenced by ANP Rapid bedside measurement of brain natriuretic peptide in patients with chronic heart failure More evidence for bedside BNP in heart failure assessment Rapid bedside measurement of brain natriuretic peptide in patients with chronic heart failure N-Terminal Pro-B-Type Natriuretic Peptide and Long-Term Mortality in Acute Coronary Syndromes More evidence for bedside BNP in heart failure assessment Local of C-ANP Suppresses Inflammation, Eliminates Shear Stress-Induced Thrombosis Prevents Neointima Brain Natriuretic Peptide Measurement in Acute Coronary Syndromes Potentiation of Natriuretic Peptide Limits Polymorphonuclear Neutrophil-Vascular Cell Interactions Atrial natriuretic factor inhibits mitogen-induced growth in aortic smooth muscle cells Vasopressin-dependent Inhibition of the C-type Natriuretic Peptide receptor A-type natriuretic peptide receptor in the spontaneously hypertensive rat Atrial natriuretic factor inhibits mitogen-induced growth in aortic smooth muscle cells Variability of Nt-proANP and C-ANP Natriuretic peptides as markers of patent ductus arteriosus in preterm infants Natriuretic peptide system in fetal heart and circulation impact of B-type natriuretic peptide levels on the diagnoses and management of congestive heart failure Utility of a BNP as a marker for RV dysfunction in acute pulmonary embolism Usefulness of plasma N-terminal proatrial natriuretic peptide (proANP) as an early predictor of outcome in unstable angina pectoris or non-ST-elevation acute myocardial infarction The atrial natriuretic peptide-a changing view Rapid Measurement of B-Type Natriuretic Peptide in the Emergency Diagnosis of Heart Failure Prognostic value of N-terminal pro-atrial and pro-brain natriuretic peptide in patients with acute coronary syndromes Plasma ProANP1–30 Reflects Salt Sensitivity in Subjects With Heredity for Hypertension Plasma atrial natriuretic peptide concentration inversely correlates with left atrial collagen volume fraction in patients with atrial fibrillation N-terminal pro brain natriuretic peptide on admission for early risk stratification of patients with chest pain and no ST-segment elevation Natriuretic peptides in the diagnosis of heart disease-First amongst equals Molecular cloning and functional characterization of the upstream rat atrial natriuretic peptide promoter Increased plasma brain natriuretic peptide level as a guide for silent myocardial ischemia in patients with non-obstructive hypertrophic cardiomyopathy Impact of age and sex on plasma natriuretic peptide levels in healthy adults Evaluation of the atrial natriuretic peptide gene in stroke Divergent effects of ANP and BNP in acute heart failure B-type natriuretic peptide after percutaneous transluminal septal myocardial ablation B-Type Natriuretic Peptide-A Window to the Heart Biochemistry and physiology of the natriuretic peptide receptor guanylyl cyclases Atrial natriuretic peptide level after cardioversion of chronic atrial fibrillation Atrial natriuretic peptide in atrial fibrillation association of variant of nitric oxide synthase gene Glu298-Asp polymorphism

Last Modified: 2004-08-15