Protein C pathways

       　蛋白质C系统主要包括蛋白质C、凝血酶调制素、蛋白质S和蛋白质C抑制物等。蛋白质C以酶原形式存在于血浆中，凝血酶与血管内皮细胞上的凝血酶调制素结合而激活蛋白质C。它在内皮系统、血液凝固及先天免疫反应等方面具有特殊的作用。为此CMBI特准备了Protein C pathways的特别报道，供研究参考，更多文献请用相关关键词通过CMBI文献查询获取。

• Why do animal models (sometimes) fail to mimic human sepsis
  
• Tissue factor, coagulation proteases, and protease-activated receptors in endotoxemia and sepsis
  
• Thrombin activatable fibrinolysis inhibitor
  
• Structure and functions of the endothelial cell protein C receptor
  
• Severe protein C deficiency predicts early death in severe sepsis
  
• Radiation injury and the protein C pathway
  
• Protein S-A conduit between anticoagulation and inflammation
  
• Protein C-activated protein C pathway
  
• Protective role of activated protein C in lung and airway remodeling
  
• Protease-activated receptor signaling in the regulation of inflammation
  
• Platelet factor 4 modulation of the thrombomodulin-protein C system
  
• Plasma protein C levels in patients with acute lung injury
  
• Novel functions of thrombomodulin in inflammation
  
• Importance of hemostatic gene polymorphisms for susceptibility to and outcome of severe sepsis
  
• Human models of endotoxemia and recombinant human activated protein C
  
• Factor V Leiden polymorphism modifies sepsis outcome
  
• factor V Leiden polymorphism in severe sepsis and on treatment with recombinant protein C
  
• Endpoints in sepsis trials
  
• Endothelium as an organ system
  
• endothelial protein C receptor and thrombomodulin in inflammatory bowel disease
  
• Endogenous protein C activation in patients with severe sepsis
  
• Effect of drotrecogin alfa (activated) on human endothelial cell permeability and Rho kinase signaling
  
• Activated protein C and ischemic stroke
  
• Activated protein C and ischemia-reperfusion injury
  
• Introduction to the Fifth Margaux Conference on Critical Illness-Protein C pathways-Bedside to bench