Toll Like Receptors (TLR)

       　TLR是细胞表面一类受体，它在炎症、免疫、病源体识别中都起着十分重要的作用。因此参与许多疾病的发病过程，与传染病、肿瘤、心血管病、自身免 疫性疾病、过敏等都有着密切关系。它亦是研究和开发新药的一个新的靶点，故受到国际医学生物学广泛关注。为此CMBI特准备了关于Toll Like Receptors (TLR)的特别报道，供实践参考。更多文献,请用相关关键词通过CMBI文献查询获取。

• Viruses and Toll-like receptors
  
• Toll-like receptors
  
• Toll-like receptors-function and roles in lung disease
  
• Toll-like receptors, endogenous ligands, and systemic autoimmune disease
  
• Toll-like receptors on astrocytes
  
• Toll-like receptors in the pathogenesis of human disease
  
• Toll-like receptors in rheumatoid arthritis joint
  
• Toll-like receptors in innate immunity
  
• Toll-like receptors in giant cell arteritis
  
• Toll-like receptors in cardiovascular diseases
  
• Toll-like receptors and their signaling mechanisms
  
• Toll-like receptors and their role in the development of autoimmune diseases
  
• toll-like receptors and their potential roles in kidney disease
  
• Toll-like receptors and the genetics of innate immunity
  
• Toll-like receptors and other links between innate and acquired alloimmunity
  
• Toll-like receptors and NOD2
  
• Toll-like receptors and microbes take aim at each other
  
• Toll-like receptors and innate antifungal responses
  
• Toll-like receptors and inflammation in the CNS
  
• Toll-like receptors and dendritic cells
  
• Toll-like receptors and acquired immunity
  
• TICAM-1 and TICAM-2-toll-like receptor adapters
  
• The role of Toll-like receptors in the host response to viruses
  
• The role of Toll-like receptors in combating mycobacteria
  
• The role of Toll-like receptors and Nod proteins in bacterial infection
  
• The role of toll-like receptor 9 in the intestine
  
• The role of epithelial Toll-like receptor expression in host defense and microbial tolerance
  
• Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease
  
• Signaling in B cells via Toll-like receptors
  
• Role of Toll-like receptors in pathogen recognition
  
• Role of Toll-like receptors in antisense and siRNA
  
• Regulators of the Toll and Imd pathways in the Drosophila innate immune response
  
• Reading the viral signature by Toll-like receptors and other pattern recognition receptors
  
• potential for Toll-like receptors to collaborate with other innate immune receptors
  
• Pleiotropic function of Toll-like receptors
  
• Negative regulation of toll-like receptor-mediated immune responses
  
• Modulation of Toll-interleukin 1 receptor mediated signaling
  
• Modulating vaccine responses with dendritic cells and Toll-like receptors
  
• Mammalian Toll-like receptors
  
• Leucine-rich repeats and pathogen recognition in Toll-like receptors
  
• Is targeting Toll-like receptors and their signaling pathway
  
• Innate immunity, Toll-like receptors and host response to infection
  
• Innate immunity via Toll-like receptors and Nod proteins
  
• Innate immunity and toll-like receptors
  
• Innate immunity and organ transplantation
  
• Inherited disorders of human Toll-like receptor signaling
  
• Induction of antigen cross-presentation by Toll-like receptors
  
• HIV expression-evidence for a role of Toll-like receptors
  
• Functions of toll-like receptors
  
• Functional role for toll-like receptors in atherosclerosis and arterial remodeling
  
• Evolution and integration of innate immune recognition systems
  
• Differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression
  
• Chemokines and Toll-like receptors in Lyme disease pathogenesis
  
• Toll-like receptors-balancing host resistance with immune tolerance
  
• Adenosine receptors and mammalian toll-like receptors
  
• Adaptor usage and Toll-like receptor signaling specificity
  
• Acute exposure to ethanol affects Toll-like receptor signaling and subsequent responses
  
• A novel negative regulator for IL-1 receptor and Toll-like receptor 4