Domain Database



Domain Database
无论是基础实验还是临床实践，都要靠数据来记录和承载过程和结果。随着基础和临床技术效率的不断提高，相应的产生了大量的数据，而这些数据量之庞大，已经超出了人力的承受范围。所以，数据库技术被运用到领域中来，为领域数据的效率运用提供了可行之路。而针对某一领域实际运用、整合了数据库创建者对领域的知识和了解的数据库，就能在目前为业者提供更大的助力，于是大批的领域数据库在形式需要下而大量出现。CMBI自2001年开始，就着力这方面的工作，先后构建了Cardio（心血管疾病相关基因与蛋白质数据库），BioPD（生物活性多肽数据库）、ARDB（肾上腺素能受体数据库）、CVHDB（心血管相关中草药数据库）等与心血管领域运用相关的领域数据库，且取得了一点成果。在此为读者CMBI将最新的关于Domain Database的文献集结成辑，供实践参考。更多文献,请用相关关键词通过CMBI文献查询获取。
CMBI已发表文献 Cardio: a web-based knowledge resource of genes and proteins related to cardiovascular disease BioPD: a web-based information center for bioactive peptides 心血管领域数据库 Legal Issues Relating to a Cardiac Surgery Database A National Cardiac Surgery Database-Current Achievements and Future Challenges A National Cardiac Surgery Database Peer Review and Quality Assurance in Cardiac Surgery The Potential Role of Health and Welfare in a National Cardiac Surgery Database Data Analysis for the National Cardiac Surgery Database Implementation of a Victorian Cardiac Surgery Database Developing Performance Indicators for Cardiac Surgery Towards a Statewide Cardiac Surgery Database Why Australia Needs a Cardiac Procedures Database Global Cardiovascular Infobase 微生物与传染病领域数据库 Clinical trial database Evaluation of drug information databases for personal digital assistants Use of a state-wide administrative database in assessing a regional trauma system web based GIS service for feedback of surveillance data on communicable diseases Getting organized-a simple database solution to replace laboratory notebooks PASS2-a semi-automated database of Protein Alignments Organised as Structural Superfamilies medicine-phenylketonuria-PAHdb 2003-What a locus-specific knowledgebase can do GPCR-GRAPA-LIB-a refined library of hidden Markov Models for annotating GPCRs MENDB-a database of polymorphic loci from natural populations MHCBN-a comprehensive database of MHC binding and non-binding peptides The UMD-p53 database-New mutations and analysis tools The Z curve database-a graphic representation of genome sequences TRAIT (TRAnscript Integrated Table)-a knowledgebase of human skeletal muscle transcripts The database of databases rSNP_Guide-An integrated database-tools system for studying SNPs and site-directed mutations in transcription factor binding sites The human SHOX mutation database VIRTUAL2D-A web-accessible predictive database for proteomics analysis The Ethics of Health Sector Databases eMelanoBase-An online locus-specific variant database for familial melanoma 肿瘤领域数据库 The Mouse Tumor Biology Database 1 The Mouse Tumor Biology Database 2 其他领域数据库 Compilation of a MALDI-TOF mass spectral database for the rapid screening and characterisation of bacteria implicated in human infectious diseases BioPD-a web-based information center for bioactive peptides- A database for 'intronless' genes in eukaryotic genomes Analysing microarray-based CGH experiments. genetics-The Genetic Association Database A SNP-centric database for the investigation of the human genome MuTrack-a genome analysis system for large-scale mutagenesis in the mouse PASS2-an automated database of protein alignments organised as structural superfamilies The PROF_PAT Protein Pattern Database The Genomic Threading Database Variations and increase in use of statins across Europe-data from administrative databases SMoS-a database of structural motifs of protein superfamilies imm-IMGT-ONTOLOGY and IMGT databases, tools and Web resources for immunogenetics and immunoinformatics IMGT-ONTOLOGY and IMGT databases, tools and Web resources for immunogenetics and immunoinformatics Ca-The Mouse Tumor Biology Database Allergen Databases Database For Renal Collecting Duct Regulatory And Transporter Proteins Gala,-Database For Genomic Sequence Alignments And Annotations Ideg6-A Web Tool For Detection Of Differentially Expressed Genes In Multiple Tag Sampling Experiments Kinase Pathway Database-An Integrated Protein-Kinase And Nlp-Based Protein-Interaction Resource From biological databases to platforms for biomedical discovery Comparative Genomic Tools And Databases cell-signal-Signaling PAthway Database (SPAD) End-Results Program Database as a Resource for Descriptive Epidemiologic and Clinical Human Gene Mutation Database (HGMD-FONT-2003 update INTEGRATING BIOLOGICAL DATABASES RettBASE-The IRSA MECP2 variation database Signaling PAthway Database The human SHOX mutation database ProbID-A probabilistic algorithm to identify peptides through sequence database searching using tandem mass spectral data rSNP_Guide-An integrated database-tools system for studying SNPs and site-directed mutations in transcription factor binding sites A kinase sequence database-sequence alignments and family assignment New electron microscopy database and deposition system TFBS-Computational framework for transcription factor binding site analysis SEGE-A database on intron less-single exonic genes from eukaryotes DOLOP—database of bacterial lipoproteins EMBL-Align- a new public nucleotide and amino acid multiple sequence alignment database JenPep-a database of quantitative functional peptide data for immunology A database of transcriptional start sites Analysis and comparison of metabolic pathway databases Describing Biological Protein Interactions in Terms of Protein States and State Transitions-THE LiveDIP DATABASE The Mouse Tumor Biology Database prostate cancer databases The Comparative RNA Web (CRW) site-an online database MDB-a database system utilizing automatic construction of modules and STAR-derived universal language TRIPLES database-a community resource for yeast molecular biology Genomic and Proteomic Databases; Large-Scale Analysis and Integration of Data RiceGAAS-an automated annotation system and database for rice genome sequence VirOligo-a database of virus-specific oligonucleotides RIDOM-Ribosomal Differentiation of Medical Micro-organisms Database NUREBASE-database of nuclear hormone receptors PlasmoDB-the Plasmodium genome resource. An integrated database providing tools for accessing, analyzing and mapping expression and sequence data CSDBase-an interactive database for cold shock domain-containing proteins and the bacterial cold shock response FANTOM DB-database of Functional Annotation of RIKEN Mouse cDNA Clones Histone Database MEROPS-the protease database ProTherm, Thermodynamic Database for Proteins and Mutants PROSITE database, its status in 2002 MMDB-Entrez’s 3D-structure database Molecular Biology Database Collection-2002 update suPFAM—a database of potential protein superfamily relationships derived by comparing sequence-based and structure-based families quest to deduce protein function from sequence-the role of pattern databases GTOP-a database of protein structures predicted from genome sequences HOWDY-an integrated database system for human genome research Database Category-Varied Biomedical Content FUGOID-functional genomics of organellar introns database euGenes-a eukaryote genome information system human (PEDB) and mouse (mPEDB) Prostate Expression Databases ASTRAL compendium enhancements Database Category-Pathology IMB Jena Image Library of Biological Macromolecules-2002 update SYSTERS, GeneNest, SpliceNest-exploring sequence space from genome to protein NCIR-a database of non-canonical interactions in known RNA structures Pfam Protein Families Database Homophila-human disease gene cognates in Drosophila Gene Expression Omnibus-NCBI gene expression and hybridization array data repository Database Category-Alphabetical Database List YPL.db-the Yeast Protein Localization database EcoCyc Database Saccharomyces Genome Database (SGD) provides secondary gene annotation using the Gene Ontology (GO) The SBASE protein domain library, release 9.0-an online resource for protein domain identification Transterm-a database of mRNAs and translational control elements Database Category-Mutation Databases BRENDA, enzyme data and metabolic information SWEET-DB-an attempt to create annotated data collections for carbohydrates PALS db-Putative Alternative Splicing database DNA Data Bank of Japan (DDBJ) for genome scale research in life science GeneNet-a database on structure and functional organisation of gene networks InBase-the Intein Database HUGE-a database for human large proteins identified in the Kazusa cDNA sequencing project PASS2-a semi-automated database of Protein Alignments Organised as Structural Superfamilies MagnaportheDB-a federated solution for integrating physical and genetic map data with BAC end derived sequences for the rice blast fungus Magnaporthe grisea Database Category-RNA Sequences MAGEST-Maboya Gene Expression patterns and Sequence Tags UTRdb and UTRsite-specialized databases of sequences and functional elements of 5' and 3' untranslated regions of eukaryotic mRNAs TTD-Therapeutic Target Database EXProt-a database for proteins with an experimentally verified function DIP, the Database of Interacting Proteins-a research tool for studying cellular networks of protein interactions DBTSS-DataBase of human Transcriptional Start Sites and full-length cDNAs PharmGKB-the Pharmacogenetics Knowledge Base MitoNuc-a database of nuclear genes coding for mitochondrial proteins. Update 2002 JSNP-a database of common gene variations in the Japanese population Protein Information Resource-an integrated public resource of functional annotation of proteins GenBank Database Category-Genetic and Physical Maps Genew-the Human Gene Nomenclature Database tGRAP, the G-protein coupled receptors mutant database SUPERFAMILY-HMMs representing all proteins of known structure The androgen receptor gene mutations database KEGG databases at GenomeNet CKAAPs DB-a Conserved Key Amino Acid Positions DataBase 5S Ribosomal RNA Database Update of AMmtDB-a database of multi-aligned Metazoa mitochondrial DNA sequences The MetaCyc Database Database Category-Retrieval Systems and Database Structure SubtiList-the reference database for the Bacillus subtilis genome Comparative Genometrics (CG)-a database dedicated to biometric comparisons of whole genomes MDB-the Metalloprotein Database and Browser at The Scripps Research Institute HGVbase-a human sequence variation database emphasizing data quality and a broad spectrum of data sources Database Category-Comparative Genomics READ-RIKEN Expression Array Database FlyBase database of the Drosophila genome projects and community literature Celera Discovery SystemTM SCOR-a Structural Classification of RNA database Wanda-a database of duplicated fish genes MIPS-a database for genomes and protein sequences Protein Data Bank-unifying the archive Eukaryotic Promoter Database, EPD Sentra, a database of signal transduction proteins IDR-the ImmunoDeficiency Resource Recent improvements to the SMART domain-based sequence annotation resource Transcription Regulatory Regions Database (TRRD) LIGAND-database of chemical compounds and reactions in biological pathways The Mouse Genome Database (MGD)-the model organism database for the laboratory mouse The tmRNA Website-invasion by an intron Database Category-Structure MIPS Arabidopsis thaliana Database (MAtDB)-an integrated biological knowledge resource MODBASE, a database of annotated comparative protein structure models FIMM, a database of functional molecular immunology update 2002 European database on small subunit ribosomal RNA yMGV-helping biologists with yeast microarray data mining ASPD (Artificially Selected Proteins-Peptides Database)-a database of proteins and peptides evolved in vitro A comprehensive leukemia database Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders FLAGdb-FST-a database of mapped flanking insertion sites (FSTs) of Arabidopsis AraC-XylS database-a family of positive transcriptional regulators in bacteria CDD-a database of conserved domain alignments with links to domain three-dimensional structure Database Category-Protein Databases Ensembl genome database project Database Category-Transgenics Rat Genome Database (RGD)-mapping disease onto the genome HugeIndex-a database with visualization tools for high-density oligonucleotide array data from normal human tissues Gramene-a resource for comparative grass genomics S-MARt DB-a database on scaffold-matrix attached regions Database Category-Metabolic Pathways and Cellular Regulation SELEX_DB-a databaseon in vitro selected oligomers adapted for recognizing natural sites and for analyzing both SNPs and site-directed mutagenesis data Database Category-Genomic Databases Database Category-Protein Sequence Motifs PRINTS and PRINTS-S shed light on protein ancestry HOX Pro DB-the functional genomics of hox ensembles Database Category-Major Sequence Repositories-1 Genome Information Broker (GIB)-data retrieval and comparative analysis system for completed microbial genomes and more Olfactory Receptor Database-a metadata-driven automated population from sources of gene and protein sequences Predictome-a database of putative functional links between proteins Annotating the human proteome-the Human Proteome Survey Database (HumanPSDTM) and an in-depth target database for G protein-coupled receptors (GPCR-PDTM) from Incyte Genomics HERVd-database of human endogenous retroviruses PlantCARE, a database of plant cis-acting regulatory elements and a portal to tools for in silico analysis of promoter sequences Database Category-Intermolecular Interactions SCOP database in 2002-refinements accommodate structural genomics Progenetix.net-an online repository for molecular cytogenetic aberration data ExInt-an Exon Intron Database The EMBL Nucleotide Sequence Database Gene Resource Locator-gene locus maps for transcriptome analysis AngioDB-database of angiogenesis and angiogenesis-related molecules DT40 web site-sampling and connecting the genes of a B cell line Database resources of the National Center for Biotechnology Information-2002 update Genomic database resources for Dictyostelium discoideum Database Category-Proteome Resources TRANSCompel-a database on composite regulatory elements in eukaryotic genes Database Category-Gene Identification and Structure PLANT-PIs-a database for plant protease inhibitors and their genes Database Category-Gene Expression A Review of Locus-Specific Mutation Databases Nuclear protein database Functional Genomic Analysis of an Organ-Specific Database ca-The Mouse Tumor Biology Database ageing-AGEID-a database of aging genes and interventions The CATH protein family database-A resource for structural and functional annotation of genomes RADARS, a bioinformatics solution that automates proteome mass spectral analysis, optimises protein identification, and archives data in a relational database EPPS-mining the COG database by an extended phylogenetic patterns search INTEGRATING BIOLOGICAL DATABASES Pathways database system-an integrated system for biological pathways proteome-VIRTUAL2D-A web-accessible predictive database for proteomics analysis Quality and completeness of SNP databases A new database for seed oil fatty acids Biomedical databases-protecting privacy and promoting research 3MOTIF-visualizing conserved protein sequence motifs in the protein structure database ORFer – retrieval of protein sequences and ORF from GenBank and storage into databases Neuroimaging Databases The GENETPIG database-a tool for comparative mapping in pig The Homeodomain Resource ToxoDB-accessing the Toxoplasma gondii genome BSD-the Biodegradative Strain Database GPCRDB information system for G protein-coupled receptors mRDB (tmRNA database) Sputnik-a database platform for comparative plant genomics The Mitochondrial Protein Import Machinery of Plants (MPIMP) database The Protein Information Resource The SWISS-PROT protein knowledgebase and its supplement TrEMBL TMPDB-a database of experimentally-characterized transmembrane topologies Ensembl 2002-accommodating comparative genomics Gene3D-structural assignments for the biologist and bioinformaticist alike HGT-DB-a database of putative horizontally transferred genes in prokaryotic complete genomes Integration of related sequences with protein three-dimensional structural families in an updated version of PALI database MEPD-a Medaka gene expression pattern database MOsDB-an integrated information resource for rice genomics RTKdb-database of receptor tyrosine kinase SOURCE-a unified genomic resource of functional annotations, ontologies, and gene expression data The ERGOTM genome analysis and discovery system The UCSC Genome Browser Database BayGenomics-a resource of insertional mutations in mouse embryonic stem cells CATMA-a complete Arabidopsis GST database Database resources of the National Center for Biotechnology MitoDrome-a database of Drosophila melanogaster nuclear genes encoding proteins targeted to the mitochondrion NESbase version 1.0-a database of nuclear export signals OGRe-a relational database for comparative analysis of mitochondrial genomes Ribosomal Database Project (RDP-II)-previewing a new autoaligner that allows regular updates and the new prokaryotic taxonomy The EMBL Nucleotide Sequence Database-major new developments TIGRFAMs database of protein families E-MSD-the European Bioinformatics Institute Macromolecular Structure Database GenBank IRESdb-the Internal Ribosome Entry Site database Online Mendelian Inheritance in Animals (OMIA)-a comparative knowledgebase of genetic disorders and other familial traits in non-laboratory animals Plant snoRNA database TRANSPATH-an integrated database on signal transduction and a tool for array analysis IMGT, the international ImMunoGeneTics database The European Bioinformatics Institute's data resources The MetaFMF website-a high quality tool for meta-analysis of FMF ARED 2.0-an update of AU-rich element mRNA database ASAP, a systematic annotation package for community analysis of genomes CDD-a curated Entrez database of conserved domain alignments DNA Data Bank of Japan (DDBJ) in XML InterDom-a database of putative interacting protein domains for validating predicted protein interactions and complexes MtDB-a database for personalized data mining of the model legume Medicago truncatula transcriptome PEDANT genome database SubViral RNA-a database of the smallest known auto-replicable RNA species CADB-Conformation Angles DataBase of proteins CATH database-an extended protein family resource for structural and functional genomics CnidBase-The Cnidarian Evolutionary Genomics Database INFEVERS-the Registry for FMF and hereditary inflammatory disorders mutations PGDB-a curated and integrated database of genes related to the prostate PlantProm-a database of plant promoter sequences RECODE 2003 Rfam-an RNA family database The Arabidopsis SeedGenes Project The SNP Consortium website-past, present and future TRANSFAC-transcriptional regulation, from patterns to profiles Database for mobile group II introns Human immunodeficiency virus reverse transcriptase and protease sequence database ProtoNet-hierarchical classification of the protein space RTPrimerDB-the Real-Time PCR primer and probe database WorfDB-the Caenorhabditis elegans ORFeome Database WormBase-a cross-species database for comparative genomics Active Sequences Collection (ASC) database-a new tool to assign functions to protein sequences ASAP-the Alternative Splicing Annotation Project PEP-Predictions for Entire Proteomes PlasmoDB-the Plasmodium genome resource. A database integrating experimental and computational data PRODORIC-prokaryotic database of gene regulation Arabidopsis Information Resource (TAIR)-a model organism database providing a centralized, curated gateway to Arabidopsis biology GrainGenes, the genome database for small-grain crops IMGT-HLA and IMGTMHC-sequence databases for the study of the major histocompatibility complex NetAffx-Affymetrix probesets and annotations PRINTS and its automatic supplement, prePRINTS SRPDB-Signal Recognition Particle Database The SBASE domain sequence library, release 10-domain architecture prediction Atlas of Genetics and Cytogenetics in Oncology and Haematology Improvements to CluSTr-the database of SWISS-PROT+TrEMBL protein clusters KDBI-Kinetic Data of Bio-molecular Interactions database MICdb-database of prokaryotic microsatellites MMDB-Entrez's 3D-structure database NCBI Reference Sequence Project-update and current status NLSdb-database of nuclear localization signals Noncoding regulatory RNAs database ParaDB-a tool for paralogy mapping in vertebrate genomes The Stanford Microarray Database-data access and quality assessment tools Human Gene-Centric Databases at the Weizmann Institute of Science NTDB-Thermodynamic Database for Nucleic Acids SDAP-database and computational tools for allergenic proteins Enlarged FAMSBASE-protein 3D structure models of genome sequences for 41 species GénoPlante-Info (GPI)-a collection of databases and bioinformatics resources for plant genomics NRMD-Nuclear Receptor Mutation Database PLMItRNA, a database on the heterogeneous genetic origin of mitochondrial tRNA genes and tRNAs in photosynthetic eukaryotes ProClass-an integrated database of protein family, function and structure information STRING-a database of predicted functional associations between proteins The Lipase Engineering Database-a navigation and analysis tool for protein families The Nuclear Protein Database (NPD)-sub-nuclear localisation and functional annotation of the nuclear proteome The Zebrafish Information Network (ZFIN) ALFRED-the ALelle FREquency Database MolMovDB-analysis and visualization of conformational change and structural flexibility Proteome Analysis database-a tool for the in silico analysis of whole proteomes REBASE-restriction enzymes and methyltransferases rSNP_Guide, a database system for analysis of transcription factor binding to DNA with variations Saccharomyces Genome Database (SGD) provides biochemical and structural information for budding yeast proteins The InterPro Database, 2003 brings increased coverage and new features CORG-a database for COmparative Regulatory Genomics FlyBase database of the Drosophila genome projects and community literature MBGD-microbial genome database for comparative analysis PACRAT-a database and analysis system for archaeal and bacterial intergenic sequence features The University of Minnesota Biocatalysis-Biodegradation Database ZmDB, an integrated database for maize genome research An improved version of the DNA methylation database (MethDB ArrayExpress—a public repository for microarray gene expression data at the EBI DSMM-a Database of Simulated Molecular Motions GOBASE—a database of mitochondrial and chloroplast information MTID-a database of Sleeping Beauty transposon insertions in mice PANTHER-a browsable database of gene products organized by biological function, using curated protein family and subfamily classification The Molecular Biology Database Collection- 2003 update ADME-AP-a database of ADME associated proteins Local structure-based sequence profile database for local and global protein structure predictions Modeling the percolation of annotation errors in a database of protein sequences A hierarchical approach to aligning collinear regions of genomes PFDB-a generic protein family database integrating the CATH domain structure database with sequence based protein family resources SNPper-retrieval and analysis of human SNPs The evolution of structural databases

Last Modified: 2004-10-17