DNA疫苗

       　DNA疫苗也称核酸免疫是直接应用编码的抗原DNA载体，直接导入机体内，表达出蛋白质，进而通过细胞和体液免疫反应，产生抗体，而 达到防治疾病的一种方法。这种方法与传统免疫的方法具有巨大的优越性，对肿瘤和感染等许多疾病都有重要的应用前景，是当前免疫治疗中 的一个热点，为此CMBI特准备了DNA疫苗的特别报道，供研究参考，更多文献请用相关关键词通过CMBI文献查询获取。

• DNA vaccines—back in the saddle again
  
• DNA vaccine-Mucosal immunization against dental caries with plasmid DNA encoding pac gene of Streptococcus mutans in rats
  
• DNA vaccine-Enhancement of DNA vaccine potency in rhesus macaques by electroporation
  
• DNA vaccine-efficacy of electroporated plasmid vaccines correlates with long-term antigen production in vivo
  
• Bacteriophage lambda is a highly stable DNA vaccine delivery vehicle
  
• Use of CpG oligodeoxynucleotides as immune adjuvants
  
• The processing of antigens delivered as DNA vaccines
  
• Targeting plasmid-encoded proteins to the antigen presentation pathways
  
• Strategies for improved formulation and delivery of DNA vaccines to veterinary target species
  
• Progress in DNA-based heterologous prime-boost immunization strategies for malaria
  
• Molecular adjuvants for mucosal immunity
  
• Modulating vaccine responses with dendritic cells and Toll-like receptors
  
• Microparticles for the delivery of DNA vaccines
  
• Expression library immunization to discover and improve vaccine antigens
  
• Enhancement of human immunodeficiency virus type 1-DNA vaccine potency
  
• DNA vaccines suppress tumor growth and metastases by the induction of anti-angiogenesis
  
• DNA vaccines expressing antigens with a stress protein-capturing domain display enhanced immunogenicity
  
• DNA vaccines and adjuvants
  
• DNA vaccines against human immunodeficiency virus type 1
  
• DNA fusion gene vaccines against cancer
  
• Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens
  
• Cancer immunotherapy with mRNA-transfected dendritic cells
  
• B lymphocytes as antigen-presenting cell-based genetic vaccines
  
• Antigen-immunostimulatory oligonucleotide conjugates
  
• DNA vaccines against the human papillomavirus type 16 E6 or E7 oncoproteins
  
• Induction of SARS-nucleoprotein-specific immune response by use of DNA vaccine
  
• Improvement of DNA vaccine immunogenicity by a dual antigen expression system
  
• Topical delivery of imiquimod to a mouse model as a novel adjuvant for human immunodeficiency virus (HIV) DNA
  
• Safety, tolerability, and antibody responses in humans after sequential immunization with a PfCSP DNA vaccine
  
• Reverse transcriptase-based DNA vaccines against drug-resistant HIV-1 tested in a mouse model
  
• Resiquimod is a modest adjuvant for HIV-1 gag-based genetic immunization
  
• Pulmonary delivery of chitosan-DNA nanoparticles enhances the immunogenicity of a DNA vaccine encoding HLA-A
  
• Priming of piglets against enterotoxigenic E
  
• polypeptide size and intracellular sorting on the induction of epitope-specific CTL responses by DNA vaccines
  
• Mouse strain-dependent differences in enhancement of immune responses by C3d
  
• Molecular studies on the diversification of hemagglutinin––specific human neonatal repertoire subsequent to immunization with naked DNA
  
• Long-term persistence of vaccination and HAART to human immunodeficiency virus (HIV
  
• Influence of maternal antibodies on Chlamydophila psittaci-specific immune responses in turkeys elicited by naked DNA
  
• Independent but not synergistic enhancement to the immunogenicity of DNA vaccine expressing HIV-1 gp120 glycoprotein
  
• In vivo electroporation improves immune responses to DNA vaccination in sheep
  
• Immunization with hepatitis C virus core gene triggers potent T-cell response
  
• Genetic immunization against anthrax
  
• Genetic immunisation against hepatitis B using whole bacteriophage
  
• DNA vaccination in utero
  
• DNA immunisation with minimalistic expression constructs
  
• Development of venom toxin-specific antibodies by DNA immunisation
  
• Designing and engineering of DNA-vaccine construction encoding multiple CTL-epitopes of major HIV-1 antigens
  
• CTLA-4 blockade in combination with xenogeneic DNA vaccines enhances T-cell responses, tumor immunity and autoimmunity to self antigens
  
• Comparison of the immune response to a self antigen after DNA immunisation
  
• comparative evaluation of different DNA vaccine candidates against experimental murine leishmaniasis
  
• Co-immunization with plasmid IL-12 generates a strong T-cell memory response
  
• Co-delivery of pro-apoptotic BAX with a DNA vaccine recruits dendritic cells and promotes efficacy of autoimmune diabetes prevention
  
• analysis using a mouse model of the immunogenicity of artificial VLP and attenuated Salmonella strain carrying a DNA-vaccine encoding HIV-1
  
• adjuvants for DNA vaccination by particle-mediated immunotherapeutic
  
• DNA Vaccines
  
• Influence of routes and administration parameters on antibody response of pigs following DNA vaccination
  
• In vivo electroporation of skeletal muscles increases the efficacy of Japanese encephalitis virus DNA vaccine
  
• Immunisation against PCV2 structural protein by DNA vaccination
  
• Gene immunization may induce secondary antibodies reacting with DNA
  
• A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice
  
• DNA Vaccines against Human Immunodeficiency Virus Type 1 in the Past Decade
  
• Reduced immunogenicity of DNA vaccine plasmids in mixtures
  
• DNA vaccine-encapsulated virus-like particles derived from an orally transmissible virus stimulate mucosal
  
• Treatment of bladder carcinomas using recombinant BCG DNA vaccines and electroporative gene immunotherapy
  
• DNA vaccine coding for the full-length infectious Kunjin virus RNA protects mice against the New York strain of West Nile virus
  
• Rabies Dna Vaccines For Protection And Therapeutic Treatment
  
• Hpv Dna Vaccines
  
• Dna Vaccines For Non-Infectious Diseases-New Treatments For Tumour And Allergy
  
• DNA vaccine coding for the full-length infectious Kunjin virus RNA protects mice
  
• Dna Vaccine Against Malaria
  
• Anti-Idiotypic Dna Vaccines For B-Cell Lymphoma Therapy
  
• On The Use Of Dna Vaccines For The Prophylaxis Of Mycobacterial Diseases
  
• Therapeutic Effect Of Dna Vaccines Combined With Chemotherapy In-Latent Infection Model After Aerosol Infection Of Mice With Mycobacterium Tuberculosis
  
• Intravascular Naked Dna Vaccine Encoding Glycoprotein B Induces Protective Humoral And Cellular Immunity
  
• Signal Sequence Deletion And Fusion To Tetanus Toxoid Epitope Augment Antitumor Immune Responses To-Human Carcinoembryonic Antigen (Cea) Plasmid Dna Vaccine In-Murine Test System
  
• Pml-Rara–targeted Dna Vaccine Induces Protective Immunity In A Mouse Model Of Leukemia
  
• Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis
  
• Enhancing Dna Vaccine Potency By Coadministration Of Dna Encoding Antiapoptotic Proteins
  
• Dna Vaccines And Apoptosis
  
• A DNA vaccine containing inverted terminal repeats from adeno-associated virus increases immunity to HIV
  
• DNA vaccines
  
• Progress in DNA vaccine for prophylaxis and therapy of hepatitis B
  
• Needle-free-Fetal immunization by a DNA vaccine delivered into the oral cavity
  
• Alphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathways
  
• A DNA vaccine against VEGF receptor 2 prevents effective angiogenesis
  
• Anti-idiotypic DNA vaccines for B-cell lymphoma therapy
  
• Delivering Gene Therapy-Development of Polyplex-based DNA Vaccines
  
• cationic sub-micron emulsion (MF59-DOTAP) is an effective delivery system for DNA vaccines
  
• Dendritic cell discoveries provide new insight into the cellular immunobiology of DNA vaccines
  
• ANTIBODY -DNA Vaccines-Aunology, Application, and Optimization
  
• Designer Vaccines for the 21st Century
  
• Preventing AIDS But Not HIV-1 Infection with a DNA Vaccine
  
• A Toll for DNA vaccines
  
• Recent advances in the use of DNA vaccines for the treatment of diseases
  
• Immunology of DNA vaccines- CpG motifs and antigen presentation
  
• Downstream processing of plasmid DNA for gene therapy and DNA vaccine applications
  
• Current status of DNA vaccines
  
• Application of DNA vaccine technology to aquaculture
  
• DNA vaccines- a key for inducing long-term cellular immunity
  
• DNA Vaccines- Immunology, Application, and Optimization
  
• Out on the farm with DNA vaccines
  
• DNA vaccines-delivery
  
• DNA vaccine tab-2
  
• DNA vaccine -tab-1
  
• DNA vaccine fig