Telomeres and Telomerase in Diseases

       　近年来，端粒（telomere）、端粒酶（telomerase）同衰老、癌症的关系是生命科学研究的热点之一，研究中人们发现“衰老者的端粒缩短”，而且在约85%的肿瘤细胞中检测到了端粒酶活性。因此对端粒及端粒酶系统的研究，有助于阐明细胞衰老和恶变的机制，对抗衰老以及肿瘤的诊断、治疗都具有重要的理论和实际意义。我们曾在158期做过相关报导。因此CMBI特准备了关于Telomeres and Telomerase in Diseases的相关文献，供大家参考。更多文献，请用相关关键词通过CMBI文献查询获取。

• CELL-Telomeres and Telomerase in Diseases
  
• Dyskeratosis Congenita-A Disease of Dysfunctional Telomere Maintenance
  
• Extratelomeric Functions of Telomerase
  
• In the End, it's all Structure
  
• Modeling Premature Aging Syndromes with the Telomerase Knockout Mouse
  
• Skin Aging-A Role for Telomerase and Telomere Dynamics
  
• Telomerase Therapeutics for Degenerative Diseases
  
• Telomerase-Dependent Gene Therapy
  
• Telomere and Telomerase Dynamics in Human Cells
  
• Telomere Dynamics in Hematopoietic Stem Cells
  
• Telomere Dynamics in Response to Chemotherapy
  
• Telomere Induced Senescence
  
• Telomere Maintenance and Tumorigenesis
  
• Telomeres as Biomarkers for Ageing and Age-Related Diseases
  
• Telomeres, Crisis and Cancer
  
• Telomeres, Telomerase and Malignant Transformation