PiRNA和Piwi

       piRNA (Piwi-interacting RNA) 是最近从哺乳动物睾丸组织中发现的一类能与PIWI 蛋白质相互作用，且长度分布在26～31 nt 的新型小分子单链RNA， 它们在精子的产生中发挥作用。Piwi蛋白代表着Ago蛋白家族中的一个分支(subclade)，参与对siRNA调节的DNA降解过程，调节着生殖细胞的成熟。此次CMBI特准备了关于PiRNA和Piwi相关文献，供大家参考。更多文献，请用相关关键词通过CMBI文献查询获取。

• Non-coding RNAs
  
• ca-MicroRNAs in biological processes and carcinogenesis
  
• Transcriptional silencing of a transgene by RNAi in the soma of C. elegans
  
• The Role of PIWI and the miRNA Machinery in Drosophila Germline Determination
  
• Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis-
  
• Stem-cell protein Piwil2 is widely expressed in tumors and inhibits apoptosis
  
• Seawi-a sea urchin piwi-argonaute family member is a component of MT-RNP complexes
  
• RNAdb 2.0—an expanded database of mammalian non-coding RNAs
  
• Regulatory Relationship among piwi, pumilio, and bag-of-marbles in Drosophila Germline Stem Cell Self-Renewal and Differentiation
  
• Polycomb, pairing and PIWI – RNA silencing and nuclear interactions
  
• Piwi-interacting RNAs (piRNAs) in mammalian testes
  
• On the origin and functions of RNA-mediated silencing
  
• mRNA degradation by miRNAs and GW182 requires both CCR4
  
• miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis
  
• MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis
  
• Gene Circuitry Controlling a Stem Cell Niche
  
• DjPiwi-1, a member of the PAZ-Piwi gene family, defines a subpopulation of planarian stem cells
  
• Characterization of the piRNA Complex from Rat Testes
  
• Argonaute-a scaffold for the function of short regulatory RNAs
  
• A Third Way to Silence RNA
  
• A novel class of small RNAs in mouse spermatogenic cells
  
• A novel class of small RNAs bind to MILI protein in mouse testes
  
• A New RNA Dimension to Genome Control