Gene Regulation

       传统认识下，基因调控是通过蛋白转录因子来实现的。近年来，不断有新的基因调控系统被发现。最重要的可能就是microRNAs(miRNAs)，不断有新的研究成果证实microRNAs在基因调控中的作用，继而也与很多疾病相关联上。另一个新发现的调控系统--也是基于RNA的--核糖开关(riboswitch)，广泛存在于真菌、植物中。此次CMBI特从Science等杂志摘录了Gene Regulation相关文献，供大家参考。更多文献，请用相关关键词通过CMBI文献查询获取。

• Gene Regulation
• Complex Riboswitches
• Evolution of Eukaryotic Transcription Circuits
• Gene Regulation by Transcription Factors and MicroRNAs ---
• Gene Regulation in the Third Dimension
• MicroRNAs Make Big Impression in Disease After Disease
• Multilevel Regulation of Gene Expression by MicroRNAs
• The Eukaryotic Genome as an RNA Machine
• Transcription Regulation Through Promoter-Proximal Pausing of RNA Polymerase II
• IGF2- Epigenetic regulation and role in development and disease
• Krüppel-like transcription factors
• Mechanisms of microRNA-mediated gene regulation in animal cells
• Methylphenidate and cocaine- the same effects on gene regulation
• Modulation of mRNA stability as a novel therapeutic approach
• Non-coding RNAs, epigenetics and complexity
• Regulation of gene transcription by mitogen-activated protein kinase signaling pathways
• RNA-binding proteins and post-transcriptional gene regulation
• Computational epigenetics
• Epigenetic gene regulation
• Hepatic Gene Regulation by Glucose and Polyunsaturated Fatty Acids
• PI3K, RSK, and mTOR Signal Networks for the GST Gene Regulation
• Polymorphic miRNA-mediated gene regulation
• Regulation of GATA1 Gene Expression
• Transcriptional interference